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    MAPK8 mitogen-activated protein kinase 8 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 450445, updated on 3-Apr-2024

    Summary

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    Official Symbol
    MAPK8provided by VGNC
    Official Full Name
    mitogen-activated protein kinase 8provided by VGNC
    Primary source
    VGNC:VGNC:14517
    Locus tag
    CK820_G0047803
    See related
    Ensembl:ENSPTRG00000002478
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 10
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 8 NC_072406.2 (60611629..60739614)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 10 NC_072408.1 (51276058..51404009)

    Chromosome 8 - NC_072406.2Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase non-receptor type 20 Neighboring gene uncharacterized LOC107966683 Neighboring gene FERM and PDZ domain containing 2 Neighboring gene Rho GTPase activating protein 22 Neighboring gene WDFY family member 4 Neighboring gene uncharacterized LOC107966686

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables JUN kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in JNK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to mechanical stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitogen-activated protein kinase 8
    XP_001136927.1
    XP_009438618.1
    XP_009438619.1
    XP_009438620.1
    XP_016773710.1
    XP_016773711.1
    XP_016773713.1
    XP_016773714.1
    XP_016773715.1
    XP_016773717.1
    XP_016773718.1
    XP_016773719.1
    XP_016773720.1
    XP_016773721.1
    XP_016773722.1
    XP_054515514.1
    XP_054515515.1
    XP_054515516.1
    XP_054515518.1
    XP_054515519.1
    XP_054515520.1
    XP_054515521.1
    XP_054515522.1
    XP_063637831.1
    XP_063637833.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      60611629..60739614
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009440345.5 → XP_009438620.1  mitogen-activated protein kinase 8 isoform X4

      See identical proteins and their annotated locations for XP_009438620.1

      UniProtKB/TrEMBL
      A0A2J8JGL3, A0A2J8L2S2
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    2. XM_054659545.2 → XP_054515520.1  mitogen-activated protein kinase 8 isoform X4

      UniProtKB/TrEMBL
      A0A2J8JGL3

    3. XM_016918232.4 → XP_016773721.1  mitogen-activated protein kinase 8 isoform X4

      UniProtKB/TrEMBL
      A0A2J8JGL3, A0A2J8L2S2
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    4. XM_016918226.4 → XP_016773715.1  mitogen-activated protein kinase 8 isoform X2

      UniProtKB/TrEMBL
      A0A2J8JGK3, A0A2J8L2T2, A0A6D2VTT2, H2R0G7
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    5. XM_016918230.4 → XP_016773719.1  mitogen-activated protein kinase 8 isoform X3

      UniProtKB/TrEMBL
      A0A2J8JGK4, A0A2J8JGM8
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    6. XM_016918222.4 → XP_016773711.1  mitogen-activated protein kinase 8 isoform X1

      UniProtKB/TrEMBL
      A0A2J8JGK6, A0A2J8L2S5, A0A6D2XDJ7, K7CZW7
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    7. XM_016918231.4 → XP_016773720.1  mitogen-activated protein kinase 8 isoform X4

      UniProtKB/TrEMBL
      A0A2J8JGL3, A0A2J8L2S2
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    8. XM_016918224.4 → XP_016773713.1  mitogen-activated protein kinase 8 isoform X2

      UniProtKB/TrEMBL
      A0A2J8JGK3, A0A2J8L2T2, A0A6D2VTT2, H2R0G7
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    9. XM_016918229.4 → XP_016773718.1  mitogen-activated protein kinase 8 isoform X3

      UniProtKB/TrEMBL
      A0A2J8JGK4, A0A2J8JGM8
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    10. XM_016918221.4 → XP_016773710.1  mitogen-activated protein kinase 8 isoform X1

      UniProtKB/TrEMBL
      A0A2J8JGK6, A0A2J8L2S5, A0A6D2XDJ7, K7CZW7
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    11. XM_009440343.5 → XP_009438618.1  mitogen-activated protein kinase 8 isoform X2

      See identical proteins and their annotated locations for XP_009438618.1

      UniProtKB/TrEMBL
      A0A2J8JGK3, A0A2J8L2T2, A0A6D2VTT2, H2R0G7
      Related
      ENSPTRP00000040692.4
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    12. XM_009440344.5 → XP_009438619.1  mitogen-activated protein kinase 8 isoform X3

      See identical proteins and their annotated locations for XP_009438619.1

      UniProtKB/TrEMBL
      A0A2J8JGK4, A0A2J8JGM8
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    13. XM_001136927.5 → XP_001136927.1  mitogen-activated protein kinase 8 isoform X1

      See identical proteins and their annotated locations for XP_001136927.1

      UniProtKB/TrEMBL
      A0A2J8JGK6, A0A2J8L2S5, A0A6D2XDJ7, K7CZW7
      Related
      ENSPTRP00000091347.1
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    14. XM_016918233.4 → XP_016773722.1  mitogen-activated protein kinase 8 isoform X4

      UniProtKB/TrEMBL
      A0A2J8JGL3, A0A2J8L2S2
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    15. XM_016918228.4 → XP_016773717.1  mitogen-activated protein kinase 8 isoform X2

      UniProtKB/TrEMBL
      A0A2J8JGK3, A0A2J8L2T2, A0A6D2VTT2, H2R0G7
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    16. XM_054659543.2 → XP_054515518.1  mitogen-activated protein kinase 8 isoform X3

      UniProtKB/TrEMBL
      A0A2J8JGK4

    17. XM_016918225.4 → XP_016773714.1  mitogen-activated protein kinase 8 isoform X1

      UniProtKB/TrEMBL
      A0A2J8JGK6, A0A2J8L2S5, A0A6D2XDJ7, K7CZW7
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    18. XM_054659547.2 → XP_054515522.1  mitogen-activated protein kinase 8 isoform X4

      UniProtKB/TrEMBL
      A0A2J8JGL3

    19. XM_054659540.2 → XP_054515515.1  mitogen-activated protein kinase 8 isoform X2

      UniProtKB/TrEMBL
      A0A2J8JGK3, A0A6D2VTT2, H2R0G7

    20. XM_054659544.2 → XP_054515519.1  mitogen-activated protein kinase 8 isoform X3

      UniProtKB/TrEMBL
      A0A2J8JGK4

    21. XM_054659539.2 → XP_054515514.1  mitogen-activated protein kinase 8 isoform X1

      UniProtKB/TrEMBL
      A0A2J8JGK6, A0A6D2XDJ7, K7CZW7

    22. XM_054659546.2 → XP_054515521.1  mitogen-activated protein kinase 8 isoform X4

      UniProtKB/TrEMBL
      A0A2J8JGL3

    23. XM_063781761.1 → XP_063637831.1  mitogen-activated protein kinase 8 isoform X1

      UniProtKB/TrEMBL
      A0A2J8JGK6, A0A6D2XDJ7, K7CZW7

    24. XM_063781763.1 → XP_063637833.1  mitogen-activated protein kinase 8 isoform X4

      UniProtKB/TrEMBL
      A0A2J8JGL3

    25. XM_054659541.2 → XP_054515516.1  mitogen-activated protein kinase 8 isoform X1

      UniProtKB/TrEMBL
      A0A2J8JGK6, A0A6D2XDJ7, K7CZW7

    RNA

    1. XR_001706592.3 RNA Sequence

    2. XR_001706591.3 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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