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    CG44002 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33535, updated on 10-May-2024

    Summary

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    Official Symbol
    CG44002provided by FlyBase
    Primary source
    FLYBASE:FBgn0264744
    Locus tag
    Dmel_CG44002
    See related
    AllianceGenome:FB:FBgn0264744
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG18555; CG34406; CG34406-2; Dmel\CG44002
    Summary
    Enables DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    Location:
    23D4-23D4; 2-8 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (3169820..3171092, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (3169820..3171092, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene alpha/beta hydrolase2 Neighboring gene transfer RNA:Serine-AGA 2-3 Neighboring gene pseudo Neighboring gene transfer RNA:Serine-AGA 2-4 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An efficient and cost-effective protocol for selecting transcription factor binding sites that reduces isotope usage. Krystel J, et al. J Biomol Tech, 2012 Jul. PMID 22951958, Free PMC Article
    2. Global analysis of target genes of 21 members of the ZAD transcription factor family in Drosophila melanogaster. Krystel J, et al. Gene, 2013 Jan 10. PMID 23085320, Free PMC Article
    3. Genomic expansion and clustering of ZAD-containing C2H2 zinc-finger genes in Drosophila. Chung HR, et al. EMBO Rep, 2002 Dec. PMID 12446571, Free PMC Article
    4. An RNA-interference screen in Drosophila to identify ZAD-containing C2H2 zinc finger genes that function in female germ cells. Shapiro-Kulnane L, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561227, Free PMC Article
    5. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila. Kasinathan B, et al. Elife, 2020 Nov 10. PMID 33169670, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG44002-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      3169820..3171092 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134910.3 → NP_608754.1  uncharacterized protein Dmel_CG44002 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608754.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      R9PY35
      Related
      FBpp0306251
      Conserved Domains (4) summary
      COG5048
      Location:162 → 302
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:202 → 222
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:5 → 78
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam13465
      Location:270 → 293
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    R9PY35 R9PY35

    Gene LinkOut

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