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Links from PubChem Compound
- Official
Symbol
- As3mtprovided by RGD
- Official
Full Name
- arsenite methyltransferaseprovided by RGD
- Primary source
-
RGD:621325
- See related
-
Ensembl:ENSRNOG00000020081
AllianceGenome:RGD:621325
- Gene type
- protein coding
- RefSeq status
- VALIDATED
- Organism
-
Rattus norvegicus
- Lineage
- Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
- Also known as
- Cyt19
- Summary
- Enables arsenite methyltransferase activity and methylarsonite methyltransferase activity. Involved in arsonoacetate metabolic process and toxin metabolic process. Acts upstream of or within response to arsenic-containing substance. Located in cytosol. Orthologous to human AS3MT (arsenite methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
- Expression
- Biased expression in Liver (RPKM 936.0), Adrenal (RPKM 211.8) and 6 other tissues See more
- Orthologs
-
human
mouse
all
-
NEW
-
Try the new Gene table
Try the new Transcript table
- Exon count:
- 12
Annotation release |
Status |
Assembly |
Chr
|
Location |
RS_2024_02 |
current |
GRCr8 (GCF_036323735.1) |
1 |
NC_086019.1 (255536879..255569245) |
RS_2023_06 |
previous assembly |
mRatBN7.2 (GCF_015227675.2) |
1 |
NC_051336.1 (245595939..245628921) |
106
|
previous assembly |
Rnor_6.0 (GCF_000001895.5) |
1 |
NC_005100.4 (266482787..266514570) |
Chromosome 1 - NC_086019.1
- Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
- Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
- BioProject: PRJNA238328
- Publication:
PMID 24510058
- Analysis date: Mon Jun 6 17:44:12 2016
-
Glutathione modulates recombinant rat arsenic (+3 oxidation state) methyltransferase-catalyzed formation of trimethylarsine oxide and trimethylarsine.
Waters SB, et al. Chem Res Toxicol, 2004 Dec. PMID 15606138
-
Elucidating the pathway for arsenic methylation.
Thomas DJ, et al. Toxicol Appl Pharmacol, 2004 Aug 1. PMID 15276411
-
A novel S-adenosyl-L-methionine:arsenic(III) methyltransferase from rat liver cytosol.
Lin S, et al. J Biol Chem, 2002 Mar 29. PMID 11790780
-
Arsenic (+3 oxidation state) methyltransferase and the inorganic arsenic methylation phenotype.
Li J, et al. Toxicol Appl Pharmacol, 2005 Apr 15. PMID 15808521
-
Interactive Effects of N6AMT1 and As3MT in Arsenic Biomethylation.
Zhang H, et al. Toxicol Sci, 2015 Aug. PMID 25997655, Free PMC Article
See all (9) citations in PubMed
Products |
Interactant |
Other Gene |
Complex |
Source |
Pubs |
Description |
- Preferred Names
- arsenite methyltransferase
- Names
- S-adenosyl-L-methionine:arsenic(III) methyltransferase
- S-adenosylmethionine:arsenic (III) methyltransferase
- arsenic (+3 oxidation state) methyltransferase
- methylarsonite methyltransferase
- methyltransferase Cyt19
- NP_543166.2
-
- XP_038938593.2
-
- XP_038938624.1
-
- XP_063127220.1
-
- XP_063127291.1
-
The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.
Molecular Biology Databases
- Bgee database
- BioGPS
- CREB Target Gene Database
- CTD: Comparative Toxicogenomics Database
- GlyGen glycoinformatics resource
- Ingenuity Pathways Analysis
- Kyoto Encyclopedia of Genes and Genomes
- OMA Browser: Orthologous MAtrix
- OrthoDB catalog of orthologs
- PANTHER Classification System
- PhosphoSitePlus
Research Materials
- Addgene Non-profit plasmid repository
- ExactAntigen/Labome
- GenScript latest version of gene cDNA ORF Clone
- GeneCopoeia Inc.
- OriGene