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    col-65 Nematode cuticle collagen N-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 187138, updated on 18-Sep-2024

    Summary

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    Official Symbol
    col-65
    Official Full Name
    Nematode cuticle collagen N-terminal domain-containing protein
    Primary source
    WormBase:WBGene00000641
    Locus tag
    CELE_K08C9.4
    See related
    AllianceGenome:WB:WBGene00000641
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of cuticle. Human ortholog(s) of this gene implicated in asthma; lung disease (multiple); respiratory syncytial virus infectious disease; and rhinitis. Orthologous to human SFTPD (surfactant protein D). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (11489158..11490578, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene DUF1176 domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of cuticle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of collagen trimer IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nematode cuticle collagen N-terminal domain-containing protein
    NP_492936.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      11489158..11490578 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060535.3 → NP_492936.1  Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492936.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XUT4
      Conserved Domains (3) summary
      pfam01391
      Location:149 → 204
      Collagen; Collagen triple helix repeat (20 copies)
      smart01088
      Location:4 → 56
      Col_cuticle_N; Nematode cuticle collagen N-terminal domain
      PHA03169
      Location:148 → 292
      PHA03169; hypothetical protein; Provisional
    Nucleotide Protein
    Heading Accession and Version

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