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    NR1I3 nuclear receptor subfamily 1 group I member 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 488653, updated on 5-Mar-2024

    Summary

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    Official Symbol
    NR1I3provided by VGNC
    Official Full Name
    nuclear receptor subfamily 1 group I member 3provided by VGNC
    Primary source
    VGNC:VGNC:43945
    See related
    Ensembl:ENSCAFG00845029218
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    CAR
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 38
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 38 NC_051842.1 (21370731..21375765)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 38 NC_006620.4 (21327778..21332809)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 38 NC_049259.1 (22082201..22087226)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 38 NC_049298.1 (21267845..21272874)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 38 NC_049779.1 (21673095..21678115)

    Chromosome 38 - NC_051842.1Genomic Context describing neighboring genes Neighboring gene myelin protein zero Neighboring gene Purkinje cell protein 4 like 1 Neighboring gene translocase of outer mitochondrial membrane 40 like Neighboring gene apolipoprotein A2 Neighboring gene Fc epsilon receptor Ig

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Nuclear receptor and target gene mRNA abundance in duodenum and colon of dogs with chronic enteropathies. Greger DL, et al. Domest Anim Endocrinol, 2006 Nov. PMID 16446074
    2. Nuclear receptor and nuclear receptor target gene messenger ribonucleic acid levels at different sites of the gastrointestinal tract and in liver of healthy dogs. Gropp FN, et al. J Anim Sci, 2006 Oct. PMID 16971569

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nuclear receptor subfamily 1 group I member 3
    Names
    constitutive androstane receptor NR1I3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051842.1 Reference ROS_Cfam_1.0

      Range
      21370731..21375765
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038448617.1 → XP_038304545.1  nuclear receptor subfamily 1 group I member 3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0JHX6, A0A8C0SJ85, A0A8I3QS93
      Related
      ENSCAFP00845040669.1, ENSCAFT00845051829.1
      Conserved Domains (2) summary
      cd07156
      Location:11 → 82
      NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
      cl11397
      Location:106 → 346
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

    2. XM_038448615.1 → XP_038304543.1  nuclear receptor subfamily 1 group I member 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0SJ85, A0A8I3QS93
      Related
      ENSCAFP00845040616.1, ENSCAFT00845051767.1
      Conserved Domains (2) summary
      cd07156
      Location:29 → 100
      NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
      cl11397
      Location:124 → 364
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

    3. XM_038448616.1 → XP_038304544.1  nuclear receptor subfamily 1 group I member 3 isoform X2

      UniProtKB/TrEMBL
      A0A8C0SJ85, A0A8I3QS93
      Conserved Domains (2) summary
      cd07156
      Location:29 → 100
      NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
      cl11397
      Location:124 → 354
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

    RNA

    1. XR_005308944.1 RNA Sequence

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049298.1 Alternate UMICH_Zoey_3.1

      Range
      21267845..21272874
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038522501.1 → XP_038378429.1  nuclear receptor subfamily 1 group I member 3 isoform X3

      Conserved Domains (2) summary
      cd07156
      Location:11 → 82
      NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
      cl11397
      Location:106 → 346
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

    2. XM_038522499.1 → XP_038378427.1  nuclear receptor subfamily 1 group I member 3 isoform X1

      Conserved Domains (2) summary
      cd07156
      Location:29 → 100
      NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
      cl11397
      Location:124 → 364
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

    3. XM_038522500.1 → XP_038378428.1  nuclear receptor subfamily 1 group I member 3 isoform X2

      Conserved Domains (2) summary
      cd07156
      Location:29 → 100
      NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
      cl11397
      Location:124 → 354
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

    RNA

    1. XR_005351822.1 RNA Sequence

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049779.1 Alternate UNSW_CanFamBas_1.0

      Range
      21673095..21678115
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038650703.1 → XP_038506631.1  nuclear receptor subfamily 1 group I member 3 isoform X3

    2. XM_038650701.1 → XP_038506629.1  nuclear receptor subfamily 1 group I member 3 isoform X1

    3. XM_038650702.1 → XP_038506630.1  nuclear receptor subfamily 1 group I member 3 isoform X2

    RNA

    1. XR_005419573.1 RNA Sequence

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049259.1 Alternate UU_Cfam_GSD_1.0

      Range
      22082201..22087226
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038586283.1 → XP_038442211.1  nuclear receptor subfamily 1 group I member 3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0JHX6, A0A8C0SJ85, A0A8I3QS93
      Conserved Domains (2) summary
      cd07156
      Location:11 → 82
      NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
      cl11397
      Location:106 → 346
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

    2. XM_038586281.1 → XP_038442209.1  nuclear receptor subfamily 1 group I member 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0SJ85, A0A8I3QS93
      Conserved Domains (2) summary
      cd07156
      Location:29 → 100
      NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
      cl11397
      Location:124 → 364
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

    3. XM_038586282.1 → XP_038442210.1  nuclear receptor subfamily 1 group I member 3 isoform X2

      UniProtKB/TrEMBL
      A0A8C0SJ85, A0A8I3QS93
      Conserved Domains (2) summary
      cd07156
      Location:29 → 100
      NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
      cl11397
      Location:124 → 354
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

    RNA

    1. XR_005385812.1 RNA Sequence

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006620.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      21327778..21332809
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038464163.1 → XP_038320091.1  nuclear receptor subfamily 1 group I member 3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0JHX6, A0A8C0SJ85, A0A8I3QS93
      Conserved Domains (2) summary
      cd07156
      Location:11 → 82
      NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
      cl11397
      Location:106 → 346
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

    2. XM_038464161.1 → XP_038320089.1  nuclear receptor subfamily 1 group I member 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0SJ85, A0A8I3QS93
      Conserved Domains (2) summary
      cd07156
      Location:29 → 100
      NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
      cl11397
      Location:124 → 364
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

    3. XM_038464162.1 → XP_038320090.1  nuclear receptor subfamily 1 group I member 3 isoform X2

      UniProtKB/TrEMBL
      A0A8C0SJ85, A0A8I3QS93
      Conserved Domains (2) summary
      cd07156
      Location:29 → 100
      NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
      cl11397
      Location:124 → 354
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

    RNA

    1. XR_005318783.1 RNA Sequence

    Nucleotide Protein
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