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    Mlxip MLX interacting protein [ Mus musculus (house mouse) ]

    Gene ID: 208104, updated on 23-Jun-2021

    Summary

    Official Symbol
    Mlxipprovided by MGI
    Official Full Name
    MLX interacting proteinprovided by MGI
    Primary source
    MGI:MGI:2141183
    See related
    Ensembl:ENSMUSG00000038342
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    M; Mo; Mir; bHLHe3; bHLHe36; AW228700
    Expression
    Ubiquitous expression in spleen adult (RPKM 18.7), colon adult (RPKM 18.0) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Mlxip in Genome Data Viewer
    Location:
    5; 5 F
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (123532438..123595998)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (123394521..123457932)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (123844828..123907941)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene 15860 Neighboring gene B cell CLL/lymphoma 7A Neighboring gene predicted gene, 23458 Neighboring gene ribosomal protein L31, pseudogene 6 Neighboring gene interleukin 31

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA0867, B930074I24

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    MLX-interacting protein
    Names
    Mlx interactor
    transcriptional activator MondoA

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133917.3NP_598678.2  MLX-interacting protein isoform 2

      See identical proteins and their annotated locations for NP_598678.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) represents the longer transcript and encodes the longer isoform (2).
      Source sequence(s)
      AK047475, AY968204, BC067045
      Consensus CDS
      CCDS19662.1
      UniProtKB/Swiss-Prot
      Q2VPU4
      UniProtKB/TrEMBL
      G5E8D8
      Related
      ENSMUSP00000064943.6, ENSMUST00000068237.12
      Conserved Domains (3) summary
      cd00083
      Location:717771
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam01698
      Location:425476
      FLO_LFY; Floricaula / Leafy protein
      cl21462
      Location:758799
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    2. NM_177582.3NP_808250.1  MLX-interacting protein isoform 1

      See identical proteins and their annotated locations for NP_808250.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) lacks several exons and includes an alternate 3' terminal exon, compared to variant 1. It encodes isoform 1 which is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AK047475, BB349293
      Consensus CDS
      CCDS39268.1
      UniProtKB/Swiss-Prot
      Q2VPU4
      UniProtKB/TrEMBL
      B2RQ56
      Related
      ENSMUSP00000107223.2, ENSMUST00000111596.8
      Conserved Domains (1) summary
      pfam01698
      Location:425476
      FLO_LFY; Floricaula / Leafy protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      123532438..123595998
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_004942473.1 RNA Sequence

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