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    AGER advanced glycosylation end-product specific receptor [ Homo sapiens (human) ]

    Gene ID: 177, updated on 17-Jun-2024

    Summary

    Official Symbol
    AGERprovided by HGNC
    Official Full Name
    advanced glycosylation end-product specific receptorprovided by HGNC
    Primary source
    HGNC:HGNC:320
    See related
    Ensembl:ENSG00000204305 MIM:600214; AllianceGenome:HGNC:320
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    RAGE; sRAGE; SCARJ1
    Summary
    The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011]
    Expression
    Biased expression in lung (RPKM 397.6) and spleen (RPKM 11.0) See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See AGER in Genome Data Viewer
    Location:
    6p21.32
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (32180969..32184253, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (32034160..32037444, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (32148746..32152030, complement)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr6:32137076-32138275 Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 1 Neighboring gene microRNA 6721 Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:32145942-32146470 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:32150105-32150623 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:32150624-32151141 Neighboring gene microRNA 6833 Neighboring gene ring finger protein 5 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:32156057-32156613 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:32157766-32158334 Neighboring gene PBX homeobox 2 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:32158721-32158899 Neighboring gene G protein signaling modulator 3 Neighboring gene notch receptor 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    EBI GWAS Catalog

    Description
    Genome-wide association study identifies five loci associated with lung function.
    EBI GWAS Catalog
    Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
    EBI GWAS Catalog
    Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
    EBI GWAS Catalog
    Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.
    EBI GWAS Catalog

    HIV-1 interactions

    Protein interactions

    Protein Gene Interaction Pubs
    Tat tat HIV-1 Tat downregulates OCLN (occludin) and LRP1 and upregulates AGER (RAGE), and in a RhoA/ROCK1 dependent manner as shown through hydroxyfasudil inhibition in hCMEC/D3 cells PubMed
    capsid gag RAGE inhibits the release of HIV-1 in terms of reduced levels of CA in virus particles and induces the accumulation of cell-associated CA PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC22357

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables S100 protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables advanced glycation end-product receptor activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    enables amyloid-beta binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables amyloid-beta binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables amyloid-beta binding NAS
    Non-traceable Author Statement
    more info
    PubMed 
    enables amyloid-beta binding TAS
    Traceable Author Statement
    more info
    PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables laminin receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables molecular adaptor activity EXP
    Inferred from Experiment
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein-containing complex binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables scavenger receptor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    enables signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables signaling receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables transmembrane signaling receptor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in astrocyte activation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell surface receptor signaling pathway TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in cellular response to amyloid-beta ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in glucose mediated signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in induction of positive chemotaxis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in inflammatory response TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in learning or memory IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in microglial cell activation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in microglial cell activation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in negative regulation of blood circulation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in negative regulation of interleukin-10 production IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of long-term synaptic depression IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of long-term synaptic potentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of long-term synaptic potentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in neuron projection development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of ERK1 and ERK2 cascade IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of JNK cascade IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of NF-kappaB transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of activated T cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of chemokine production ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in positive regulation of dendritic cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of endothelin production ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in positive regulation of heterotypic cell-cell adhesion IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of interleukin-1 beta production ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in positive regulation of interleukin-12 production IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of interleukin-6 production ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in positive regulation of monocyte chemotactic protein-1 production IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of monocyte extravasation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of non-canonical NF-kappaB signal transduction IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of p38MAPK cascade IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of protein phosphorylation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of tumor necrosis factor production ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in protein localization to membrane IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of CD4-positive, alpha-beta T cell activation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of T cell mediated cytotoxicity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of inflammatory response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of long-term synaptic potentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of non-canonical NF-kappaB signal transduction NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in regulation of p38MAPK cascade IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of p38MAPK cascade ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of spontaneous synaptic transmission IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in regulation of synaptic plasticity TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in response to amyloid-beta ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in response to amyloid-beta TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in response to hypoxia IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in response to wounding TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in transcytosis ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in transport across blood-brain barrier IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in transport across blood-brain barrier NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell junction IDA
    Inferred from Direct Assay
    more info
     
    located_in cell surface NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in fibrillar center IDA
    Inferred from Direct Assay
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
     
    located_in plasma membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     
    located_in postsynapse TAS
    Traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    advanced glycosylation end product-specific receptor
    Names
    receptor for advanced glycation end-products

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029868.2 RefSeqGene

      Range
      5000..8284
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001136.5NP_001127.1  advanced glycosylation end product-specific receptor isoform 1 precursor

      See identical proteins and their annotated locations for NP_001127.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1, also known as RAGE) represents the predominant transcript, and encodes isoform 1.
      Source sequence(s)
      AL662884
      Consensus CDS
      CCDS4746.1
      UniProtKB/Swiss-Prot
      A2BFI7, A6NKF0, A7Y2U9, B0V176, Q15109, Q15279, Q3L1R4, Q3L1R5, Q3L1R6, Q3L1R7, Q3L1R8, Q3L1S0, Q86SN1, Q9H2X7, Q9Y3R3, V5R6A3
      UniProtKB/TrEMBL
      A0A1U9X782, A0A1U9X785, A0A1U9X790
      Related
      ENSP00000364217.4, ENST00000375076.9
      Conserved Domains (3) summary
      smart00410
      Location:24117
      IG_like; Immunoglobulin like
      pfam08205
      Location:124219
      C2-set_2; CD80-like C2-set immunoglobulin domain
      pfam13927
      Location:241304
      Ig_3; Immunoglobulin domain
    2. NM_001206929.2NP_001193858.1  advanced glycosylation end product-specific receptor isoform 2 precursor

      See identical proteins and their annotated locations for NP_001193858.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2, also known as RAGE_v5) uses an alternate in-frame donor splice site at an internal coding exon compared to variant 1. This results in a longer isoform (2) containing an additional protein segment compared to isoform 1.
      Source sequence(s)
      AL662884
      Consensus CDS
      CCDS75429.1
      UniProtKB/TrEMBL
      A0A0G2JL65
      Related
      ENSP00000364210.4, ENST00000375069.7
      Conserved Domains (3) summary
      smart00410
      Location:24117
      IG_like; Immunoglobulin like
      pfam08205
      Location:124235
      C2-set_2; CD80-like C2-set immunoglobulin domain
      pfam13927
      Location:257320
      Ig_3; Immunoglobulin domain
    3. NM_001206932.2NP_001193861.1  advanced glycosylation end product-specific receptor isoform 3 precursor

      See identical proteins and their annotated locations for NP_001193861.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3, also known as RAGE_v4) uses alternate in-frame acceptor and donor splice sites at two internal coding exons compared to variant 1. This results in a shorter isoform (2) missing two internal protein segments compared to isoform 1.
      Source sequence(s)
      AL662884
      UniProtKB/TrEMBL
      A0A1U9X782, A0A1U9X790
      Conserved Domains (3) summary
      smart00410
      Location:24103
      IG_like; Immunoglobulin like
      pfam08205
      Location:110205
      C2-set_2; CD80-like C2-set immunoglobulin domain
      pfam13927
      Location:227290
      Ig_3; Immunoglobulin domain
    4. NM_001206934.2NP_001193863.1  advanced glycosylation end product-specific receptor isoform 4 precursor

      See identical proteins and their annotated locations for NP_001193863.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4, also known as RAGE_v6) lacks the penultimate coding exon, and uses alternate donor splice sites at two internal coding exons compared to variant 1. This results in a frame-shift and a shorter isoform (4) with a distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AL662884
      Consensus CDS
      CCDS56417.1
      UniProtKB/TrEMBL
      A0A0G2JL37
      Related
      ENSP00000387887.2, ENST00000438221.6
      Conserved Domains (3) summary
      smart00410
      Location:24117
      IG_like; Immunoglobulin like
      pfam08205
      Location:124235
      C2-set_2; CD80-like C2-set immunoglobulin domain
      pfam13927
      Location:257320
      Ig_3; Immunoglobulin domain
    5. NM_001206936.2NP_001193865.1  advanced glycosylation end product-specific receptor isoform 5 precursor

      See identical proteins and their annotated locations for NP_001193865.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5, also known as RAGE_v9) lacks the penultimate coding exon, and uses alternate acceptor and donor splice sites at two internal coding exons compared to variant 1. This results in a frame-shift and a shorter isoform (5) with a distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AL662884
      UniProtKB/TrEMBL
      Q101R5
      Conserved Domains (2) summary
      smart00410
      Location:24117
      IG_like; Immunoglobulin like
      pfam08205
      Location:124219
      C2-set_2; CD80-like C2-set immunoglobulin domain
    6. NM_001206940.2NP_001193869.1  advanced glycosylation end product-specific receptor isoform 6 precursor

      See identical proteins and their annotated locations for NP_001193869.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6, also known as RAGE_v1) lacks the penultimate coding exon, and uses an alternate donor splice site at another coding exon compared to variant 1. This results in a frame-shift and a shorter isoform (6, also known as esRAGE and soluble RAGE) with a distinct C-terminus compared to isoform 1. This isoform lacks the transmembrane and intracellular domains, is secreted (PMID:18089847), and thought to function as a decoy receptor that inhibits RAGE signaling, and thus prevent the pathological progression of some pathologic conditions, such as Alzheimer's disease (PMID:18431028). Variants 6 and 9 encode the same isoform.
      Source sequence(s)
      AL662884
      Consensus CDS
      CCDS56418.1
      UniProtKB/TrEMBL
      A0A0G2JJF5
      Related
      ENSP00000364195.2, ENST00000375055.6
      Conserved Domains (3) summary
      smart00410
      Location:24117
      IG_like; Immunoglobulin like
      pfam08205
      Location:124219
      C2-set_2; CD80-like C2-set immunoglobulin domain
      pfam13927
      Location:241304
      Ig_3; Immunoglobulin domain
    7. NM_001206954.2NP_001193883.1  advanced glycosylation end product-specific receptor isoform 8 precursor

      See identical proteins and their annotated locations for NP_001193883.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8, also known as RAGE_v8) lacks two internal coding exons, and uses an alternate donor splice site at another coding exon compared to variant 1. This results in a frame-shift, and a shorter isoform (8) with a distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AL662884
      UniProtKB/TrEMBL
      Q101R5
      Conserved Domains (2) summary
      smart00410
      Location:24117
      IG_like; Immunoglobulin like
      pfam08205
      Location:124219
      C2-set_2; CD80-like C2-set immunoglobulin domain
    8. NM_001206966.2NP_001193895.1  advanced glycosylation end product-specific receptor isoform 6 precursor

      See identical proteins and their annotated locations for NP_001193895.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9, also known as RAGE_v10) lacks the penultimate coding exon, and uses alternate splice sites at other exons at the 3' end compared to variant 1. This results in a frame-shift and a shorter isoform (6, also known as esRAGE and soluble RAGE) with a distinct C-terminus compared to isoform 1. Variants 6 and 9 encode the same isoform.
      Source sequence(s)
      AL662884
      Consensus CDS
      CCDS56418.1
      UniProtKB/TrEMBL
      A0A0G2JJF5
      Conserved Domains (3) summary
      smart00410
      Location:24117
      IG_like; Immunoglobulin like
      pfam08205
      Location:124219
      C2-set_2; CD80-like C2-set immunoglobulin domain
      pfam13927
      Location:241304
      Ig_3; Immunoglobulin domain
    9. NM_172197.3NP_751947.1  advanced glycosylation end product-specific receptor isoform 7 precursor

      See identical proteins and their annotated locations for NP_751947.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7, also known as RAGE_v16) uses alternate splice sites at several internal coding exons compared to variant 1. This results in a frame-shift and a shorter isoform (7, also known as hRAGEsec) with a distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AL662884
      Consensus CDS
      CCDS4747.1
      UniProtKB/TrEMBL
      A0A0G2JID9
      Related
      ENSP00000364208.3, ENST00000375067.7
      Conserved Domains (2) summary
      smart00410
      Location:24103
      IG_like; Immunoglobulin like
      pfam08205
      Location:110205
      C2-set_2; CD80-like C2-set immunoglobulin domain

    RNA

    1. NR_038190.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10, also known as RAGE_v2) is alternatively spliced at the 5' end compared to variant 1. It is represented as non-coding because the use of the 5'-most translation start codon (with a strong Kozak signal), renders this transcript a candidate for nonsense-mediated mRNA decay (NMD). Transfection studies also could not detect expression of any protein from this variant (PMID:18089847).
      Source sequence(s)
      AL662884
      Related
      ENST00000484849.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      32180969..32184253 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017010328.3XP_016865817.2  advanced glycosylation end product-specific receptor isoform X1

      UniProtKB/TrEMBL
      Q101R5
    2. XM_047418261.1XP_047274217.1  advanced glycosylation end product-specific receptor isoform X3

      UniProtKB/TrEMBL
      Q101R3, Q101R5
    3. XM_047418260.1XP_047274216.1  advanced glycosylation end product-specific receptor isoform X2

      UniProtKB/TrEMBL
      Q101R5

    Reference GRCh38.p14 ALT_REF_LOCI_1

    Genomic

    1. NT_167244.2 Reference GRCh38.p14 ALT_REF_LOCI_1

      Range
      3513571..3516855 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054328451.1XP_054184426.1  advanced glycosylation end product-specific receptor isoform X1

      UniProtKB/TrEMBL
      Q101R5
    2. XM_054328453.1XP_054184428.1  advanced glycosylation end product-specific receptor isoform X3

      UniProtKB/TrEMBL
      Q101R5
    3. XM_054328452.1XP_054184427.1  advanced glycosylation end product-specific receptor isoform X2

      UniProtKB/TrEMBL
      Q101R5

    Reference GRCh38.p14 ALT_REF_LOCI_2

    Genomic

    1. NT_113891.3 Reference GRCh38.p14 ALT_REF_LOCI_2

      Range
      3619321..3622605 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054329741.1XP_054185716.1  advanced glycosylation end product-specific receptor isoform X1

      UniProtKB/TrEMBL
      Q101R5
    2. XM_054329743.1XP_054185718.1  advanced glycosylation end product-specific receptor isoform X3

      UniProtKB/TrEMBL
      Q101R3, Q101R5
    3. XM_054329742.1XP_054185717.1  advanced glycosylation end product-specific receptor isoform X2

      UniProtKB/TrEMBL
      Q101R5

    Reference GRCh38.p14 ALT_REF_LOCI_4

    Genomic

    1. NT_167246.2 Reference GRCh38.p14 ALT_REF_LOCI_4

      Range
      3485950..3489234 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054330529.1XP_054186504.1  advanced glycosylation end product-specific receptor isoform X1

      UniProtKB/TrEMBL
      Q101R5
    2. XM_054330531.1XP_054186506.1  advanced glycosylation end product-specific receptor isoform X3

      UniProtKB/TrEMBL
      Q101R3, Q101R5
    3. XM_054330530.1XP_054186505.1  advanced glycosylation end product-specific receptor isoform X2

      UniProtKB/TrEMBL
      Q101R5

    Reference GRCh38.p14 ALT_REF_LOCI_5

    Genomic

    1. NT_167247.2 Reference GRCh38.p14 ALT_REF_LOCI_5

      Range
      3522988..3526272 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054330776.1XP_054186751.1  advanced glycosylation end product-specific receptor isoform X1

      UniProtKB/TrEMBL
      Q101R5
    2. XM_054330778.1XP_054186753.1  advanced glycosylation end product-specific receptor isoform X3

      UniProtKB/TrEMBL
      Q101R5
    3. XM_054330777.1XP_054186752.1  advanced glycosylation end product-specific receptor isoform X2

      UniProtKB/TrEMBL
      Q101R5

    Reference GRCh38.p14 ALT_REF_LOCI_6

    Genomic

    1. NT_167248.2 Reference GRCh38.p14 ALT_REF_LOCI_6

      Range
      3404170..3407454 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054331012.1XP_054186987.1  advanced glycosylation end product-specific receptor isoform X1

      UniProtKB/TrEMBL
      Q101R5
    2. XM_054331014.1XP_054186989.1  advanced glycosylation end product-specific receptor isoform X3

      UniProtKB/TrEMBL
      Q101R3, Q101R5
    3. XM_054331013.1XP_054186988.1  advanced glycosylation end product-specific receptor isoform X2

      UniProtKB/TrEMBL
      Q101R5

    Reference GRCh38.p14 ALT_REF_LOCI_7

    Genomic

    1. NT_167249.2 Reference GRCh38.p14 ALT_REF_LOCI_7

      Range
      3497176..3500460 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054331278.1XP_054187253.1  advanced glycosylation end product-specific receptor isoform X1

      UniProtKB/TrEMBL
      Q101R5
    2. XM_054331280.1XP_054187255.1  advanced glycosylation end product-specific receptor isoform X3

      UniProtKB/TrEMBL
      Q101R3, Q101R5
    3. XM_054331279.1XP_054187254.1  advanced glycosylation end product-specific receptor isoform X2

      UniProtKB/TrEMBL
      Q101R5

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      32034160..32037444 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054354413.1XP_054210388.1  advanced glycosylation end product-specific receptor isoform X1

      UniProtKB/TrEMBL
      Q101R5
    2. XM_054354415.1XP_054210390.1  advanced glycosylation end product-specific receptor isoform X3

      UniProtKB/TrEMBL
      Q101R3, Q101R5
    3. XM_054354414.1XP_054210389.1  advanced glycosylation end product-specific receptor isoform X2

      UniProtKB/TrEMBL
      Q101R5