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    Tyms thymidylate synthetase [ Cricetulus griseus (Chinese hamster) ]

    Gene ID: 100754276, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Tyms
    Gene description
    thymidylate synthetase
    See related
    Ensembl:ENSCGRG00015000262
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cricetulus griseus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
    Orthologs
    human mouse all
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    Genomic context

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    See Tyms in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003616055.1 (39415..48797)
    104 current CriGri-PICRH-1.0 (GCF_003668045.3) 2 NC_048595.1 (461561669..461571042, complement)

    NW_003616055.1Genomic Context describing neighboring genes Neighboring gene clusterin like 1 Neighboring gene enolase superfamily member 1 Neighboring gene nucleophosmin-like Neighboring gene YES proto-oncogene 1, Src family tyrosine kinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters. Aleidi SM, et al. J Biol Chem, 2015 Oct 2. PMID 26296893, Free PMC Article
    2. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables thymidylate synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in dTMP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    thymidylate synthase
    Names
    Thymidylate synthase
    thymidylate synthase-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CriGri_1.0 Primary Assembly

    Genomic

    1. NW_003616055.1 Reference CriGri_1.0 Primary Assembly

      Range
      39415..48797
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003513643.5 → XP_003513691.1  thymidylate synthase

      See identical proteins and their annotated locations for XP_003513691.1

      UniProtKB/TrEMBL
      A0A061IFK8, G3IFY1
      Conserved Domains (1) summary
      cl19097
      Location:22 → 307
      TS_Pyrimidine_HMase; Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the ...

    Alternate CriGri-PICRH-1.0

    Genomic

    1. NC_048595.1 Alternate CriGri-PICRH-1.0

      Range
      461561669..461571042 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_027398958.2 → XP_027254759.1  thymidylate synthase

      UniProtKB/TrEMBL
      A0A061IFK8, G3IFY1
      Related
      ENSCGRP00015000235.1, ENSCGRT00015000327.2
    Nucleotide Protein Strain
    Heading Accession and Version

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