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ZC3H11A zinc finger CCCH-type containing 11A [ Homo sapiens (human) ]

Gene ID: 9877, updated on 9-Feb-2020

Summary

Official Symbol
ZC3H11Aprovided by HGNC
Official Full Name
zinc finger CCCH-type containing 11Aprovided by HGNC
Primary source
HGNC:HGNC:29093
See related
Ensembl:ENSG00000058673 Ensembl:ENSG00000257315 MIM:613513
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZC3HDC11A
Expression
Ubiquitous expression in skin (RPKM 33.1), lymph node (RPKM 28.6) and 25 other tissues See more
Orthologs

Genomic context

See ZC3H11A in Genome Data Viewer
Location:
1q32.1
Exon count:
20
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (203795623..203854126)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (203764665..203823256)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ATPase plasma membrane Ca2+ transporting 4 Neighboring gene uncharacterized LOC102723543 Neighboring gene lymphocyte transmembrane adaptor 1 Neighboring gene charged multivesicular body protein 5 pseudogene Neighboring gene zinc finger BED-type containing 6 Neighboring gene ribosomal protein L35a pseudogene 5 Neighboring gene Sharpr-MPRA regulatory region 5904 Neighboring gene small nuclear ribonucleoprotein polypeptide E Neighboring gene keratin 8 pseudogene 29

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1.
NHGRI GWA Catalog

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0663, DKFZp781G2455, DKFZp686D03108, DKFZp686F14109

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
RNA export from nucleus TAS
Traceable Author Statement
more info
 
mRNA 3'-end processing TAS
Traceable Author Statement
more info
 
mRNA export from nucleus TAS
Traceable Author Statement
more info
 
poly(A)+ mRNA export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
poly(A)+ mRNA export from nucleus IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
nucleoplasm TAS
Traceable Author Statement
more info
 
colocalizes_with transcription export complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with transcription export complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
zinc finger CCCH domain-containing protein 11A
Names
zinc finger CCCH-type domain containing 11A

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001319238.2NP_001306167.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1-7 encode the same protein (isoform 1).
    Source sequence(s)
    AC114402
    Consensus CDS
    CCDS30978.1
    UniProtKB/Swiss-Prot
    O75152
    Related
    ENSP00000356183.1, ENST00000367214.5
    Conserved Domains (1) summary
    pfam15663
    Location:1110
    zf-CCCH_3; Zinc-finger containing family
  2. NM_001319239.2NP_001306168.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-7 encode the same protein (isoform 1).
    Source sequence(s)
    AC114402
    Consensus CDS
    CCDS30978.1
    UniProtKB/Swiss-Prot
    O75152
    Related
    ENSP00000333253.4, ENST00000332127.8
    Conserved Domains (1) summary
    pfam15663
    Location:1110
    zf-CCCH_3; Zinc-finger containing family
  3. NM_001350261.2NP_001337190.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-7 encode the same protein (isoform 1).
    Source sequence(s)
    AC114402
    Consensus CDS
    CCDS30978.1
    Conserved Domains (1) summary
    pfam15663
    Location:1110
    zf-CCCH_3; Zinc-finger containing family
  4. NM_001350262.2NP_001337191.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1-7 encode the same protein (isoform 1).
    Source sequence(s)
    AC114402
    Consensus CDS
    CCDS30978.1
    Conserved Domains (1) summary
    pfam15663
    Location:1110
    zf-CCCH_3; Zinc-finger containing family
  5. NM_001350263.2NP_001337192.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1-7 encode the same protein (isoform 1).
    Source sequence(s)
    AC114402
    Consensus CDS
    CCDS30978.1
    Conserved Domains (1) summary
    pfam15663
    Location:1110
    zf-CCCH_3; Zinc-finger containing family
  6. NM_001350264.2NP_001337193.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1-7 encode the same protein (isoform 1).
    Source sequence(s)
    AC114402
    Consensus CDS
    CCDS30978.1
    Conserved Domains (1) summary
    pfam15663
    Location:1110
    zf-CCCH_3; Zinc-finger containing family
  7. NM_001350265.2NP_001337194.1  zinc finger CCCH domain-containing protein 11A isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region. The encoded isoform (2) has the same N- and C-termini, but is two aa shorter than isoform 1. Variants 8 and 9 encode the same protein (isoform 2).
    Source sequence(s)
    AC114402
    Conserved Domains (1) summary
    pfam15663
    Location:1110
    zf-CCCH_3; Zinc-finger containing family
  8. NM_001350266.2NP_001337195.1  zinc finger CCCH domain-containing protein 11A isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region. The encoded isoform (2) has the same N- and C-termini, but is two aa shorter than isoform 1. Variants 8 and 9 encode the same protein (isoform 2).
    Source sequence(s)
    AC114402
    Conserved Domains (1) summary
    pfam15663
    Location:1110
    zf-CCCH_3; Zinc-finger containing family
  9. NM_001376334.1NP_001363263.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  10. NM_001376335.1NP_001363264.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  11. NM_001376336.1NP_001363265.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  12. NM_001376337.1NP_001363266.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  13. NM_001376338.1NP_001363267.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  14. NM_001376339.1NP_001363268.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  15. NM_001376340.1NP_001363269.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  16. NM_001376341.1NP_001363270.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  17. NM_001376342.1NP_001363271.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
    Related
    ENSP00000356179.1, ENST00000367210.2
  18. NM_001376343.1NP_001363272.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  19. NM_001376344.1NP_001363273.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  20. NM_001376345.1NP_001363274.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  21. NM_001376346.1NP_001363275.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  22. NM_001376347.1NP_001363276.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  23. NM_001376348.1NP_001363277.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  24. NM_001376349.1NP_001363278.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  25. NM_001376350.1NP_001363279.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  26. NM_001376351.1NP_001363280.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  27. NM_001376352.1NP_001363281.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  28. NM_001376353.1NP_001363282.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  29. NM_001376354.1NP_001363283.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  30. NM_001376355.1NP_001363284.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  31. NM_001376356.1NP_001363285.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  32. NM_001376357.1NP_001363286.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  33. NM_001376358.1NP_001363287.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  34. NM_001376359.1NP_001363288.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  35. NM_001376360.1NP_001363289.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
    Related
    ENSP00000438527.1, ENST00000545588.5
  36. NM_001376361.1NP_001363290.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  37. NM_001376362.1NP_001363291.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  38. NM_001376363.1NP_001363292.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  39. NM_001376364.1NP_001363293.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  40. NM_001376365.1NP_001363294.1  zinc finger CCCH domain-containing protein 11A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC114402
  41. NM_001376366.1NP_001363295.1  zinc finger CCCH domain-containing protein 11A isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC114402
  42. NM_001376367.1NP_001363296.1  zinc finger CCCH domain-containing protein 11A isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC114402
  43. NM_014827.6NP_055642.3  zinc finger CCCH domain-containing protein 11A isoform 1

    See identical proteins and their annotated locations for NP_055642.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-7 encode the same protein (isoform 1).
    Source sequence(s)
    AC114402
    Consensus CDS
    CCDS30978.1
    UniProtKB/Swiss-Prot
    O75152
    Related
    ENSP00000356181.3, ENST00000367212.7
    Conserved Domains (1) summary
    pfam15663
    Location:1110
    zf-CCCH_3; Zinc-finger containing family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    203795623..203854126
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011510201.1XP_011508503.1  zinc finger CCCH domain-containing protein 11A isoform X1

    See identical proteins and their annotated locations for XP_011508503.1

    UniProtKB/Swiss-Prot
    O75152
    Conserved Domains (1) summary
    pfam15663
    Location:1110
    zf-CCCH_3; Zinc-finger containing family
  2. XM_017002959.2XP_016858448.1  zinc finger CCCH domain-containing protein 11A isoform X1

    UniProtKB/Swiss-Prot
    O75152
    Conserved Domains (1) summary
    pfam15663
    Location:1110
    zf-CCCH_3; Zinc-finger containing family
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