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KIAA0408 KIAA0408 [ Homo sapiens (human) ]

Gene ID: 9729, updated on 5-Aug-2022

Summary

Official Symbol
KIAA0408provided by HGNC
Official Full Name
KIAA0408provided by HGNC
Primary source
HGNC:HGNC:21636
See related
Ensembl:ENSG00000189367 MIM:619236; AllianceGenome:HGNC:21636
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in brain (RPKM 13.3), fat (RPKM 8.5) and 14 other tissues See more
Orthologs
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Genomic context

See KIAA0408 in Genome Data Viewer
Location:
6q22.33
Exon count:
6
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (127438406..127459389, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (128627332..128648316, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (127759551..127780534, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene cornichon family AMPA receptor auxiliary protein 4 pseudogene Neighboring gene SOGA3-KIAA0408 readthrough Neighboring gene ribosomal protein L17 pseudogene 23 Neighboring gene uncharacterized LOC124901399 Neighboring gene Sharpr-MPRA regulatory region 7566

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of uncharacterized protein KIAA0408 by shRNA library screening inhibits HIV-1 replication in cultured Jurkat T-cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Readthrough SOGA3-KIAA0408

Readthrough gene: SOGA3-KIAA0408, Included gene: SOGA3

Homology

Clone Names

  • FLJ43995

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
uncharacterized protein KIAA0408

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014702.5NP_055517.3  uncharacterized protein KIAA0408

    See identical proteins and their annotated locations for NP_055517.3

    Status: VALIDATED

    Source sequence(s)
    AK125983, AL096711, AL596809
    Consensus CDS
    CCDS34531.1
    UniProtKB/Swiss-Prot
    Q6ZU52, Q7L2M2
    Related
    ENSP00000435150.2, ENST00000483725.8
    Conserved Domains (1) summary
    pfam14818
    Location:1139
    DUF4482; Domain of unknown function (DUF4482)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    127438406..127459389 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    128627332..128648316 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)