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CD101 CD101 molecule [ Homo sapiens (human) ]

Gene ID: 9398, updated on 23-Nov-2021

Summary

Official Symbol
CD101provided by HGNC
Official Full Name
CD101 moleculeprovided by HGNC
Primary source
HGNC:HGNC:5949
See related
Ensembl:ENSG00000134256 MIM:604516
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
V7; IGSF2; EWI-101
Expression
Broad expression in small intestine (RPKM 2.3), lung (RPKM 2.1) and 18 other tissues See more
Orthologs
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Genomic context

See CD101 in Genome Data Viewer
Location:
1p13.1
Exon count:
12
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (116987997..117037481)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (117544382..117579174)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene prostaglandin F2 receptor inhibitor Neighboring gene RNA, 5S ribosomal pseudogene 55 Neighboring gene Sharpr-MPRA regulatory region 2959 Neighboring gene CD101 antisense RNA 1 Neighboring gene transcription termination factor 2 Neighboring gene microRNA 942 Neighboring gene tripartite motif containing 45

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Envelope transmembrane glycoprotein gp41 env A synthetic peptide corresponding to the immunosuppressive domain (amino acids 574-592) of HIV-1 gp41 downregulates the expression of CD101 (IGSF2) in peptide-treated PBMCs PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

General protein information

Preferred Names
immunoglobulin superfamily member 2
Names
cell surface glycoprotein V7
glu-Trp-Ile EWI motif-containing protein 101
leukocyte surface protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256106.3NP_001243035.1  immunoglobulin superfamily member 2 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001243035.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 3' UTR, compared to variant 1. Variants 1, 2 and 3 all encode isoform 1.
    Source sequence(s)
    AL445231
    Consensus CDS
    CCDS891.1
    UniProtKB/Swiss-Prot
    Q93033
    Related
    ENSP00000508039.1, ENST00000682167.1
    Conserved Domains (2) summary
    smart00410
    Location:87142
    IG_like; Immunoglobulin like
    cl11960
    Location:19142
    Ig; Immunoglobulin domain
  2. NM_001256109.3NP_001243038.1  immunoglobulin superfamily member 2 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001243038.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate splice site in the 3' UTR, compared to variant 1. Variants 1, 2 and 3 all encode isoform 1.
    Source sequence(s)
    AL445231
    Consensus CDS
    CCDS891.1
    UniProtKB/Swiss-Prot
    Q93033
    Related
    ENSP00000358482.1, ENST00000369470.1
    Conserved Domains (2) summary
    smart00410
    Location:87142
    IG_like; Immunoglobulin like
    cl11960
    Location:19142
    Ig; Immunoglobulin domain
  3. NM_001256111.3NP_001243040.1  immunoglobulin superfamily member 2 isoform 2 precursor

    See identical proteins and their annotated locations for NP_001243040.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) uses an alternate in-frame splice site in the 5' coding region, and also an alternate splice site in the 3' UTR, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AL445231
    Conserved Domains (2) summary
    smart00410
    Location:762849
    IG_like; Immunoglobulin like
    cl11960
    Location:759849
    Ig; Immunoglobulin domain
  4. NM_004258.6NP_004249.2  immunoglobulin superfamily member 2 isoform 1 precursor

    See identical proteins and their annotated locations for NP_004249.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Variants 1, 2 and 3 all encode isoform 1.
    Source sequence(s)
    AL445231
    Consensus CDS
    CCDS891.1
    UniProtKB/Swiss-Prot
    Q93033
    Conserved Domains (2) summary
    smart00410
    Location:87142
    IG_like; Immunoglobulin like
    cl11960
    Location:19142
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    116987997..117037481
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017002846.2XP_016858335.1  immunoglobulin superfamily member 2 isoform X2

  2. XM_017002847.2XP_016858336.1  immunoglobulin superfamily member 2 isoform X2

  3. XM_024451002.1XP_024306770.1  immunoglobulin superfamily member 2 isoform X1

    Conserved Domains (2) summary
    smart00410
    Location:311407
    IG_like; Immunoglobulin like
    cl11960
    Location:173279
    Ig; Immunoglobulin domain
  4. XM_024451003.1XP_024306771.1  immunoglobulin superfamily member 2 isoform X1

    Conserved Domains (2) summary
    smart00410
    Location:311407
    IG_like; Immunoglobulin like
    cl11960
    Location:173279
    Ig; Immunoglobulin domain
  5. XM_024451005.1XP_024306773.1  immunoglobulin superfamily member 2 isoform X1

    Conserved Domains (2) summary
    smart00410
    Location:311407
    IG_like; Immunoglobulin like
    cl11960
    Location:173279
    Ig; Immunoglobulin domain

RNA

  1. XR_946802.3 RNA Sequence

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