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RCSD1 RCSD domain containing 1 [ Homo sapiens (human) ]

Gene ID: 92241, updated on 13-Mar-2020

Summary

Official Symbol
RCSD1provided by HGNC
Official Full Name
RCSD domain containing 1provided by HGNC
Primary source
HGNC:HGNC:28310
See related
Ensembl:ENSG00000198771 MIM:610579
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MK2S4; CAPZIP
Expression
Broad expression in lymph node (RPKM 25.8), spleen (RPKM 16.7) and 20 other tissues See more
Orthologs

Genomic context

See RCSD1 in Genome Data Viewer
Location:
1q24.2
Exon count:
9
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (167630193..167708696)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (167599474..167677933)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene GATA motif-containing MPRA enhancer 235 Neighboring gene cellular repressor of E1A stimulated genes 1 Neighboring gene ribosomal protein S18 pseudogene 4 Neighboring gene tRNA-Pro (anticodon CGG) 1-1 Neighboring gene tRNA-Pro (anticodon AGG) 2-1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ35362, MGC21854, MGC126585, MGC126611

Gene Ontology Provided by GOA

Function Evidence Code Pubs
actin filament binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cellular hyperosmotic response IDA
Inferred from Direct Assay
more info
PubMed 
skeletal muscle contraction ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
actin filament IC
Inferred by Curator
more info
PubMed 

General protein information

Preferred Names
capZ-interacting protein
Names
RCSD domain-containing protein 1
protein kinase substrate CapZIP
protein kinase substrate MK2S4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001322923.1NP_001309852.1  capZ-interacting protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL031733, AL356532
    Consensus CDS
    CCDS81396.1
    UniProtKB/TrEMBL
    B7ZKW8
    Related
    ENSP00000439409.1, ENST00000537350.5
    Conserved Domains (2) summary
    pfam05177
    Location:199299
    RCSD; RCSD region
    pfam15255
    Location:51136
    CAP-ZIP_m; WASH complex subunit CAP-Z interacting, central region
  2. NM_001322924.2NP_001309853.1  capZ-interacting protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL031733, AL356532
  3. NM_052862.4NP_443094.3  capZ-interacting protein isoform 1

    See identical proteins and their annotated locations for NP_443094.3

    Status: VALIDATED

    Source sequence(s)
    AL031733, AL356532, BC013186, BC101562, DR006615
    Consensus CDS
    CCDS1263.1
    UniProtKB/Swiss-Prot
    Q6JBY9
    Related
    ENSP00000356828.3, ENST00000367854.8
    Conserved Domains (2) summary
    pfam05177
    Location:229329
    RCSD; RCSD region
    pfam15255
    Location:81166
    CAP-ZIP_m; WASH complex subunit CAP-Z interacting, central region

RNA

  1. NR_136519.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL031733

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    167630193..167708696
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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