Format

Send to:

Choose Destination

AP5B1 adaptor related protein complex 5 subunit beta 1 [ Homo sapiens (human) ]

Gene ID: 91056, updated on 4-Jul-2021

Summary

Official Symbol
AP5B1provided by HGNC
Official Full Name
adaptor related protein complex 5 subunit beta 1provided by HGNC
Primary source
HGNC:HGNC:25104
See related
Ensembl:ENSG00000254470 MIM:614367
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AP-5; PP1030
Expression
Broad expression in bone marrow (RPKM 18.6), spleen (RPKM 4.9) and 24 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See AP5B1 in Genome Data Viewer
Location:
11q13.1
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (65773898..65780976, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (65541369..65548447, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene ribonuclease H2 subunit C Neighboring gene lysine acetyltransferase 5 Neighboring gene keratin 8 pseudogene 26 Neighboring gene OVOL1 antisense RNA 1 Neighboring gene ovo like transcriptional repressor 1 Neighboring gene sorting nexin 32 Neighboring gene cofilin 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp761E198

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in endosomal transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in endosomal transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
AP-5 complex subunit beta-1
Names
AP-5 complex subunit beta
adaptor related protein complex 5 beta 1 subunit
adaptor-related protein complex 5 beta subunit
beta5

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138368.5NP_612377.4  AP-5 complex subunit beta-1

    See identical proteins and their annotated locations for NP_612377.4

    Status: VALIDATED

    Source sequence(s)
    AP001266, BC109109, JQ313135
    Consensus CDS
    CCDS58146.1
    UniProtKB/Swiss-Prot
    Q2VPB7
    Related
    ENSP00000454303.1, ENST00000532090.3

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    65773898..65780976 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center