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Ap5b1 adaptor-related protein complex 5, beta 1 subunit [ Mus musculus (house mouse) ]

Gene ID: 381201, updated on 27-Nov-2024

Summary

Official Symbol
Ap5b1provided by MGI
Official Full Name
adaptor-related protein complex 5, beta 1 subunitprovided by MGI
Primary source
MGI:MGI:2685808
See related
Ensembl:ENSMUSG00000049562 AllianceGenome:MGI:2685808
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm962; beta-5
Summary
Predicted to be involved in endosomal transport. Predicted to be part of AP-type membrane coat adaptor complex. Orthologous to human AP5B1 (adaptor related protein complex 5 subunit beta 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in duodenum adult (RPKM 13.9), small intestine adult (RPKM 11.8) and 24 other tissues See more
Orthologs
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Genomic context

See Ap5b1 in Genome Data Viewer
Location:
19 A; 19 4.34 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (5610278..5621290)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (5560250..5571262)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene sorting nexin 32 Neighboring gene STARR-positive B cell enhancer ABC_E1208 Neighboring gene NSE3 homolog, SMC5-SMC6 complex component like Neighboring gene predicted gene, 31166 Neighboring gene ovo like zinc finger 1 Neighboring gene STARR-seq mESC enhancer starr_45393 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:5601776-5601959 Neighboring gene ribonuclease H2, subunit C Neighboring gene STARR-positive B cell enhancer ABC_E11011 Neighboring gene K(lysine) acetyltransferase 5

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in endosomal transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in endosomal transport ISO
Inferred from Sequence Orthology
more info
 
involved_in endosomal transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in vesicle-mediated transport NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
part_of AP-5 adaptor complex NAS
Non-traceable Author Statement
more info
PubMed 
part_of AP-type membrane coat adaptor complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of AP-type membrane coat adaptor complex ISO
Inferred from Sequence Orthology
more info
 
part_of AP-type membrane coat adaptor complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in late endosome NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
AP-5 complex subunit beta-1
Names
adapter-related protein complex 5 beta subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033448.3NP_001028620.1  AP-5 complex subunit beta-1

    See identical proteins and their annotated locations for NP_001028620.1

    Status: VALIDATED

    Source sequence(s)
    AC126029
    Consensus CDS
    CCDS29470.1
    UniProtKB/Swiss-Prot
    Q3TAP4
    Related
    ENSMUSP00000094042.4, ENSMUST00000096318.4
  2. NM_001362046.1NP_001348975.1  AP-5 complex subunit beta-1

    Status: VALIDATED

    Source sequence(s)
    AC126029
    Consensus CDS
    CCDS29470.1
    UniProtKB/Swiss-Prot
    Q3TAP4
    Related
    ENSMUSP00000157737.2, ENSMUST00000235575.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    5610278..5621290
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006531784.2XP_006531847.1  AP-5 complex subunit beta-1 isoform X1

    See identical proteins and their annotated locations for XP_006531847.1

    UniProtKB/Swiss-Prot
    Q3TAP4