Ap5b1 adaptor-related protein complex 5, beta 1 subunit [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ap5b1provided by MGI
Official Full Name: adaptor-related protein complex 5, beta 1 subunitprovided by MGI
Primary source: MGI:MGI:2685808
See related: Ensembl:ENSMUSG00000049562 AllianceGenome:MGI:2685808
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm962; beta-5
Summary: Predicted to be involved in endosomal transport. Predicted to act upstream of or within protein transport. Predicted to be part of AP-type membrane coat adaptor complex. Orthologous to human AP5B1 (adaptor related protein complex 5 subunit beta 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in duodenum adult (RPKM 13.9), small intestine adult (RPKM 11.8) and 24 other tissues See more
Orthologs: human all
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Genomic context

Location:: 19; 19 A

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	19	NC_000085.7 (5610278..5621290)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	19	NC_000085.6 (5560250..5571262)

Chromosome 19 - NC_000085.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Homology

Homologs of the Ap5b1 gene: The Ap5b1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, and rat.
Orthologs from Annotation Pipeline: 387 organisms have orthologs with human gene Ap5b1
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in endosomal transport	IBA Inferred from Biological aspect of Ancestor more info	PubMed
involved_in endosomal transport	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
involved_in vesicle-mediated transport	NAS Non-traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
part_of AP-5 adaptor complex	NAS Non-traceable Author Statement more info	PubMed
part_of AP-type membrane coat adaptor complex	IBA Inferred from Biological aspect of Ancestor more info	PubMed
part_of AP-type membrane coat adaptor complex	ISO Inferred from Sequence Orthology more info
located_in late endosome	NAS Non-traceable Author Statement more info	PubMed

General protein information

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Preferred Names: AP-5 complex subunit beta-1

Names: adapter-related protein complex 5 beta subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.