Format

Send to:

Choose Destination

NFKBID NFKB inhibitor delta [ Homo sapiens (human) ]

Gene ID: 84807, updated on 9-Oct-2021

Summary

Official Symbol
NFKBIDprovided by HGNC
Official Full Name
NFKB inhibitor deltaprovided by HGNC
Primary source
HGNC:HGNC:15671
See related
Ensembl:ENSG00000167604 MIM:618887
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IkBNS; TA-NFKBH; IkappaBNS
Expression
Broad expression in bone marrow (RPKM 9.7), appendix (RPKM 2.8) and 19 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See NFKBID in Genome Data Viewer
Location:
19q13.12
Exon count:
18
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (35887630..35902303, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (36378854..36393205, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107985317 Neighboring gene amyloid beta precursor like protein 1 Neighboring gene RNA, 7SL, cytoplasmic 402, pseudogene Neighboring gene hematopoietic cell signal transducer Neighboring gene transmembrane immune signaling adaptor TYROBP

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC11314, MGC149503

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in T cell receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of T-helper 17 cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
NF-kappa-B inhibitor delta
Names
I-kappa-B-delta
T-cell activation NFKB-like protein
ikB-delta
ikappaBdelta
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001321831.2NP_001308760.1  NF-kappa-B inhibitor delta isoform 2

    Status: VALIDATED

    Source sequence(s)
    AD000864, CD743210
    Conserved Domains (4) summary
    cd00204
    Location:94242
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:258293
    Ank; Ankyrin repeat
    pfam12796
    Location:104213
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:6397
    ANK; ANK repeat [structural motif]
  2. NM_001365705.1NP_001352634.1  NF-kappa-B inhibitor delta isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4), as well as variant 1, encodes isoform 1.
    Source sequence(s)
    AD000864
    Conserved Domains (3) summary
    PHA03095
    Location:46287
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:4882
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:183278
    Ank_2; Ankyrin repeats (3 copies)
  3. NM_001365706.1NP_001352635.1  NF-kappa-B inhibitor delta isoform 4

    Status: VALIDATED

    Source sequence(s)
    AD000864
    Conserved Domains (2) summary
    cd00204
    Location:44168
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:85115
    ANK; ANK repeat [structural motif]
  4. NM_032721.3NP_116110.2  NF-kappa-B inhibitor delta isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) encodes the longest isoform (3).
    Source sequence(s)
    AD000864, AF385433
    Related
    ENSP00000475712.2, ENST00000606253.5
    Conserved Domains (4) summary
    cd00204
    Location:231379
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:304355
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:334430
    Ank_2; Ankyrin repeats (3 copies)
    cl26464
    Location:70178
    Atrophin-1; Atrophin-1 family
  5. NM_139239.3NP_640332.1  NF-kappa-B inhibitor delta isoform 1

    See identical proteins and their annotated locations for NP_640332.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1), as well as variant 4, encodes isoform 1.
    Source sequence(s)
    AF385434, CD743210
    Consensus CDS
    CCDS42552.1
    UniProtKB/Swiss-Prot
    Q8NI38
    Related
    ENSP00000380109.1, ENST00000396901.5
    Conserved Domains (3) summary
    PHA03095
    Location:46287
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:4882
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:183278
    Ank_2; Ankyrin repeats (3 copies)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    35887630..35902303 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017027390.1XP_016882879.1  NF-kappa-B inhibitor delta isoform X1

    Conserved Domains (4) summary
    cd00204
    Location:94242
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:258293
    Ank; Ankyrin repeat
    pfam12796
    Location:104213
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:6397
    ANK; ANK repeat [structural motif]
  2. XM_005259340.3XP_005259397.1  NF-kappa-B inhibitor delta isoform X1

    See identical proteins and their annotated locations for XP_005259397.1

    Conserved Domains (4) summary
    cd00204
    Location:94242
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:258293
    Ank; Ankyrin repeat
    pfam12796
    Location:104213
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:6397
    ANK; ANK repeat [structural motif]
  3. XM_017027391.1XP_016882880.1  NF-kappa-B inhibitor delta isoform X3

    UniProtKB/Swiss-Prot
    Q8NI38
    Conserved Domains (3) summary
    PHA03095
    Location:46287
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:4882
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:183278
    Ank_2; Ankyrin repeats (3 copies)
  4. XM_011527421.2XP_011525723.1  NF-kappa-B inhibitor delta isoform X4

    See identical proteins and their annotated locations for XP_011525723.1

    Conserved Domains (4) summary
    cd00204
    Location:69217
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:233268
    Ank; Ankyrin repeat
    pfam12796
    Location:79188
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:75105
    ANK; ANK repeat [structural motif]
  5. XM_024451744.1XP_024307512.1  NF-kappa-B inhibitor delta isoform X7

    Conserved Domains (2) summary
    cd00204
    Location:11145
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:1161
    ANK; ANK repeat [structural motif]
  6. XM_011527420.2XP_011525722.1  NF-kappa-B inhibitor delta isoform X1

    See identical proteins and their annotated locations for XP_011525722.1

    Conserved Domains (4) summary
    cd00204
    Location:94242
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:258293
    Ank; Ankyrin repeat
    pfam12796
    Location:104213
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:6397
    ANK; ANK repeat [structural motif]
  7. XM_011527424.3XP_011525726.1  NF-kappa-B inhibitor delta isoform X1

    See identical proteins and their annotated locations for XP_011525726.1

    Conserved Domains (4) summary
    cd00204
    Location:94242
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:258293
    Ank; Ankyrin repeat
    pfam12796
    Location:104213
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:6397
    ANK; ANK repeat [structural motif]
  8. XM_017027393.1XP_016882882.1  NF-kappa-B inhibitor delta isoform X3

    UniProtKB/Swiss-Prot
    Q8NI38
    Conserved Domains (3) summary
    PHA03095
    Location:46287
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:4882
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:183278
    Ank_2; Ankyrin repeats (3 copies)
  9. XM_017027392.1XP_016882881.1  NF-kappa-B inhibitor delta isoform X3

    UniProtKB/Swiss-Prot
    Q8NI38
    Conserved Domains (3) summary
    PHA03095
    Location:46287
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:4882
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:183278
    Ank_2; Ankyrin repeats (3 copies)
  10. XM_017027395.2XP_016882884.1  NF-kappa-B inhibitor delta isoform X4

    Conserved Domains (4) summary
    cd00204
    Location:69217
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:233268
    Ank; Ankyrin repeat
    pfam12796
    Location:79188
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:75105
    ANK; ANK repeat [structural motif]
  11. XM_017027397.2XP_016882886.1  NF-kappa-B inhibitor delta isoform X6

    Conserved Domains (4) summary
    cd00204
    Location:46194
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:210245
    Ank; Ankyrin repeat
    pfam12796
    Location:56165
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:1549
    ANK; ANK repeat [structural motif]
  12. XM_017027394.1XP_016882883.1  NF-kappa-B inhibitor delta isoform X4

    Conserved Domains (4) summary
    cd00204
    Location:69217
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:233268
    Ank; Ankyrin repeat
    pfam12796
    Location:79188
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:75105
    ANK; ANK repeat [structural motif]
  13. XM_017027389.1XP_016882878.1  NF-kappa-B inhibitor delta isoform X2

RNA

  1. XR_001753773.1 RNA Sequence

Support Center