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LLPH LLP homolog, long-term synaptic facilitation factor [ Homo sapiens (human) ]

Gene ID: 84298, updated on 23-Nov-2021

Summary

Official Symbol
LLPHprovided by HGNC
Official Full Name
LLP homolog, long-term synaptic facilitation factorprovided by HGNC
Primary source
HGNC:HGNC:28229
See related
Ensembl:ENSG00000139233 MIM:616998
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
hLLP; C12orf31
Expression
Ubiquitous expression in adrenal (RPKM 19.2), bone marrow (RPKM 19.1) and 25 other tissues See more
Orthologs
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Genomic context

See LLPH in Genome Data Viewer
Location:
12q14.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (66116555..66130750, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (66510335..66524530, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene ribosomal protein L21 pseudogene 18 Neighboring gene RNA, 5S ribosomal pseudogene 362 Neighboring gene LLPH divergent transcript Neighboring gene transmembrane BAX inhibitor motif containing 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ57212, MGC14817, MGC104302

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables basal RNA polymerase II transcription machinery binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables basal RNA polymerase II transcription machinery binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in dendrite extension IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in dendrite extension ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of dendritic spine development ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in chromosome IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleolus IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
protein LLP homolog
Names
LLP homolog, long-term synaptic facilitation (Aplysia)
human LAPS18-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032338.4NP_115714.1  protein LLP homolog

    See identical proteins and their annotated locations for NP_115714.1

    Status: VALIDATED

    Source sequence(s)
    AC078927, AK091568, BM996194, KF455664
    Consensus CDS
    CCDS8974.1
    UniProtKB/Swiss-Prot
    Q9BRT6
    UniProtKB/TrEMBL
    A0A024RB76
    Related
    ENSP00000266604.2, ENST00000266604.7
    Conserved Domains (1) summary
    pfam10169
    Location:3117
    Laps; Learning-associated protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    66116555..66130750 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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