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UBL4A ubiquitin like 4A [ Homo sapiens (human) ]

Gene ID: 8266, updated on 20-Jan-2019

Summary

Official Symbol
UBL4Aprovided by HGNC
Official Full Name
ubiquitin like 4Aprovided by HGNC
Primary source
HGNC:HGNC:12505
See related
Ensembl:ENSG00000102178 MIM:312070
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GDX; G6PD; GET5; MDY2; UBL4; TMA24; DX254E; DXS254E
Expression
Ubiquitous expression in heart (RPKM 16.9), brain (RPKM 12.9) and 25 other tissues See more
Orthologs

Genomic context

See UBL4A in Genome Data Viewer
Location:
Xq28
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) X NC_000023.11 (154483717..154486670, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (153712056..153714932, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene plexin A3 Neighboring gene L antigen family member 3 Neighboring gene solute carrier family 10 member 3 Neighboring gene RNA, 7SL, cytoplasmic 697, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Vif vif HIV-1 Vif is identified to have a physical interaction with ubiquitin-like 4A (UBL4A) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
chaperone binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
ubiquitin-like protein transferase activity TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
BAT3 complex IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
ubiquitin-like protein 4A
Names
ubiquitin-like 4
ubiquitin-like protein GDX

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014235.5NP_055050.1  ubiquitin-like protein 4A

    See identical proteins and their annotated locations for NP_055050.1

    Status: VALIDATED

    Source sequence(s)
    BC043346, BM711450, CK826435, DA012854, DR003955
    Consensus CDS
    CCDS14754.1
    UniProtKB/Swiss-Prot
    P11441
    Related
    ENSP00000358674.4, ENST00000369660.8
    Conserved Domains (2) summary
    cd01807
    Location:174
    GDX_N; ubiquitin-like domain of GDX
    cl19566
    Location:95149
    RE_Alw26IDE; Type II restriction endonuclease (RE_Alw26IDE)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p12 Primary Assembly

    Range
    154483717..154486670 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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