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SRPK4 ser/arg-rich protein kinase 4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 824469, updated on 18-Sep-2024

Summary

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Official Symbol
SRPK4
Official Full Name
ser/arg-rich protein kinase 4
Primary source
TAIR:AT3G53030
Locus tag
AT3G53030
See related
Araport:AT3G53030
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ser/arg-rich protein kinase 4
Summary
Encodes a protein kinase SRPK4 that specifically targets Arabidopsis Ser/Arg-rich (SR) slicing factors involved in RNA metabolism. In vitro kinase assay showed that SRPK4 phosphorylates the SR protein RSp31.
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Genomic context

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Location:
chromosome: 3
Exon count:
4
Sequence:
Chromosome: 3; NC_003074.8 (19662195..19664553)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Ribosomal protein L24e family protein Neighboring gene late embryogenesis abundant protein, putative / LEA protein Neighboring gene D-galactoside/L-rhamnose binding SUEL lectin protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis. de la Fuente van Bentem S, et al. J Proteome Res, 2008 Jun. PMID 18433157
  2. Phosphoproteomics reveals extensive in vivo phosphorylation of Arabidopsis proteins involved in RNA metabolism. de la Fuente van Bentem S, et al. Nucleic Acids Res, 2006. PMID 16807317, Free PMC Article
  3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_115163.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within protein phosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
ser/arg-rich protein kinase 4
NP_566977.1
  • ser/arg-rich protein kinase 4 (SRPK4); FUNCTIONS IN: protein kinase activity, kinase activity; INVOLVED IN: response to oxidative stress, protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT3G44850.1); Has 38460 Blast hits to 29477 proteins in 1034 species: Archae - 2; Bacteria - 1392; Metazoa - 15648; Fungi - 7270; Plants - 6510; Viruses - 16; Other Eukaryotes - 7622 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    19662195..19664553
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_115163.5 → NP_566977.1  ser/arg-rich protein kinase 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_566977.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9XKK9, A0A654FFF7, F4J982, Q94AX8, Q9FYB3
    Conserved Domains (2) summary
    smart00220
    Location:42 → 466
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14136
    Location:31 → 466
    STKc_SRPK; Catalytic domain of the Serine/Threonine Kinase, Serine-aRginine Protein Kinase
Nucleotide Protein
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