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CDKB1;2 cyclin-dependent kinase B1;2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 818444, updated on 18-Sep-2024

Summary

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Official Symbol
CDKB1;2
Official Full Name
cyclin-dependent kinase B1;2
Primary source
TAIR:AT2G38620
Locus tag
AT2G38620
See related
Araport:AT2G38620
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
cyclin-dependent kinase B1;2; CYCLIN-DEPENDENT KINASE B1;2; T6A23.18; T6A23_18
Summary
Encodes a member of a plant specific family of cyclin dependent kinases.
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Genomic context

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Location:
chromosome: 2
Exon count:
3
Sequence:
Chromosome: 2; NC_003071.7 (16152473..16154086)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene HAD superfamily, subfamily IIIB acid phosphatase Neighboring gene RNA-binding KH domain-containing protein Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene LURP-one-like protein (DUF567) Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CDK-related protein kinases in plants. Joubès J, et al. Plant Mol Biol, 2000 Aug. PMID 11089864
  2. The plant-specific CDKB1-CYCB1 complex mediates homologous recombination repair in Arabidopsis. Weimer AK, et al. EMBO J, 2016 Oct 4. PMID 27497297, Free PMC Article
  3. FOUR LIPS and MYB88 conditionally restrict the G1/S transition during stomatal formation. Lee E, et al. J Exp Bot, 2013 Nov. PMID 24123248, Free PMC Article
  4. Regulation of cell proliferation in the stomatal lineage by the Arabidopsis MYB FOUR LIPS via direct targeting of core cell cycle genes. Xie Z, et al. Plant Cell, 2010 Jul. PMID 20675570, Free PMC Article
  5. Arabidopsis cyclin-dependent kinase C2 interacts with HDA15 and is involved in far-red light-mediated hypocotyl cell elongation. Chen CY, et al. Plant J, 2022 Dec. PMID 36367383

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001036430.3
NM_001336711.1
NM_129419.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables RNA polymerase II CTD heptapeptide repeat kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables cyclin binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein serine/threonine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in guard mother cell differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA endoreduplication IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of cell cycle TAS
Traceable Author Statement
more info
 PubMed 
involved_in regulation of cell cycle G1/S phase transition IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of stomatal complex patterning IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of cyclin-dependent protein kinase holoenzyme complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
cyclin-dependent kinase B1;2
NP_001031507.1
  • cyclin-dependent kinase B1;2 (CDKB1;2); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: cyclin-dependent kinase B1;1 (TAIR:AT3G54180.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_181396.2
  • cyclin-dependent kinase B1;2 (CDKB1;2); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: cyclin-dependent kinase B1;1 (TAIR:AT3G54180.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    16152473..16154086
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001336710.1 → NP_001324504.1  cyclin-dependent kinase B1;2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A7G2EGI0

  2. NM_001036430.3 → NP_001031507.1  cyclin-dependent kinase B1;2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031507.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q2V419, Q56XK5, Q9ZVI4
    UniProtKB/TrEMBL
    A0A5S9X5B5
    Conserved Domains (2) summary
    PLN00009
    Location:1 → 306
    PLN00009; cyclin-dependent kinase A; Provisional
    cd07837
    Location:2 → 304
    STKc_CdkB_plant; Catalytic domain of the Serine/Threonine Kinase, Plant B-type Cyclin-Dependent protein Kinase

  3. NM_129419.3 → NP_181396.2  cyclin-dependent kinase B1;2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_181396.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A7G2EGI0
    Conserved Domains (1) summary
    cl21453
    Location:2 → 237
    PKc_like; Protein Kinases, catalytic domain

  4. NM_001336711.1 → NP_001324503.1  cyclin-dependent kinase B1;2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B0A0, A0A5S9X5B5
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q2V419.2

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