U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rps27a ribosomal protein S27A [ Mus musculus (house mouse) ]

Gene ID: 78294, updated on 8-Jan-2023

Summary

Official Symbol
Rps27aprovided by MGI
Official Full Name
ribosomal protein S27Aprovided by MGI
Primary source
MGI:MGI:1925544
See related
Ensembl:ENSMUSG00000020460 AllianceGenome:MGI:1925544
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ubb; Ubc; Uba52; 0610006J14Rik
Summary
Predicted to enable protein tag and ubiquitin protein ligase binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination. Located in myelin sheath. Orthologous to human RPS27A (ribosomal protein S27a). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in liver E14 (RPKM 445.0), CNS E11.5 (RPKM 386.0) and 17 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Rps27a in Genome Data Viewer
Location:
11; 11 A3.3
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (29495842..29498040, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (29545842..29548040, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene prolyl-tRNA synthetase domain containing 1 Neighboring gene mitochondrial translational initiation factor 2 Neighboring gene clathrin heavy chain linker domain containing 1 Neighboring gene 60S ribosomal protein L7-like Neighboring gene ribosomal protein S2 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein tag IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
enables ubiquitin protein ligase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
PubMed 
involved_in modification-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translation at postsynapse NAS
Non-traceable Author Statement
more info
PubMed 
involved_in translation at presynapse NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm NAS
Non-traceable Author Statement
more info
PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
 
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
 
part_of cytosolic small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
part_of cytosolic small ribosomal subunit NAS
Non-traceable Author Statement
more info
PubMed 
located_in myelin sheath HDA PubMed 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in postsynapse NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in presynapse NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in ribosome NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in synapse EXP
Inferred from Experiment
more info
PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in synapse NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
ubiquitin-40S ribosomal protein S27a
Names
ubiquitin carboxyl extension protein 80

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033865.1NP_001029037.1  ubiquitin-40S ribosomal protein S27a precursor

    See identical proteins and their annotated locations for NP_001029037.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    BX284634
    Consensus CDS
    CCDS24497.1
    UniProtKB/Swiss-Prot
    P62983
    UniProtKB/TrEMBL
    A0A6P5QUL4, A0A8C6HWG5, Q642L7
    Related
    ENSMUSP00000099908.4, ENSMUST00000102844.4
    Conserved Domains (2) summary
    cd01803
    Location:176
    Ubl_ubiquitin; ubiquitin-like (Ubl) domain found in ubiquitin
    pfam01599
    Location:103147
    Ribosomal_S27; Ribosomal protein S27a
  2. NM_024277.2NP_077239.1  ubiquitin-40S ribosomal protein S27a precursor

    See identical proteins and their annotated locations for NP_077239.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    BX284634
    Consensus CDS
    CCDS24497.1
    UniProtKB/Swiss-Prot
    P62983
    UniProtKB/TrEMBL
    A0A6P5QUL4, A0A8C6HWG5, Q642L7
    Related
    ENSMUSP00000099909.5, ENSMUST00000102845.11
    Conserved Domains (2) summary
    cd01803
    Location:176
    Ubl_ubiquitin; ubiquitin-like (Ubl) domain found in ubiquitin
    pfam01599
    Location:103147
    Ribosomal_S27; Ribosomal protein S27a

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    29495842..29498040 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)