4CXC,4BPE


Conserved Protein Domain Family
Ribosomal_S27

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pfam01599: Ribosomal_S27 (this model, PSSM-Id:396259 is obsolete and has been replaced by 460261)
Ribosomal protein S27a
This family of ribosomal proteins consists mainly of the 40S ribosomal protein S27a which is synthesized as a C-terminal extension of ubiquitin (CEP). The S27a domain compromises the C-terminal half of the protein. The synthesis of ribosomal proteins as extensions of ubiquitin promotes their incorporation into nascent ribosomes by a transient metabolic stabilisation and is required for efficient ribosome biogenesis. The ribosomal extension protein S27a contains a basic region that is proposed to form a zinc finger; its fusion gene is proposed as a mechanism to maintain a fixed ratio between ubiquitin necessary for degrading proteins and ribosomes a source of proteins.
Statistics
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PSSM-Id: 396259
Aligned: 62 rows
Threshold Bit Score: 43.7234
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4CXC_FF              103 LKYYKVDE-NGKISRLRRECPSdeCGAGVFMASHFD---RHYCGKCCLT 147
A0B8S9                 4 HKYYQLSG--ETIKARKPICPR--CGNGVFLAEHED---RMSCGRCGYT 45  Methanothrix thermoacetophila PT
WP_013720493          15 SKYYELGG--DTIKSRKSVCPR--CGNGVFLADHGD---RQSCGKCGYT 56  Methanothrix soehngenii
CBRAS:FFONT_1334       5 HNYYEYDYkTKTIKLKNKRCPR--C--GSIMGHYKEpteRWYCGSCGYT 49  Fervidicoccus fontis Kam940
WP_013328056           6 YTYYKVED--DKAVTEKKHCPR--CGPGVFMAEHKD---RVSCGKCGYT 47  Methanolacinia
jgi:Maeo_0284         11 HNYYKVEG--DKVEKLKKECPR--CKGGVFMAEHLN---RFACGKCGYT 52  Methanococcus aeolicus Nankai-3
P54031                10 YKYYKIEG--DKVIRLKKTCPR--CGPGVFMAEHLN---RYACGKCGYM 51  Methanocaldococcus jannaschii DSM 2661
goetting:Ngar_c26980  15 YKFYKVSG--DKVTRSRRDCPR--CGKGTFMAEHKD---RFTCGKCGFT 56  Candidatus Nitrososphaera gargensis Ga9.2
A9A217                12 YAYFKVDG--DKVSRIKKVCSR--CGKGTYMSEHKD---RNTCGKCGLT 53  Nitrosopumilus maritimus SCM1
CBN75122              75 LKFYRVDD-TGKVQRLRKSCPNdeCGVGVRMAVHKD---RFYCGKCGLT 119 Ectocarpus siliculosus
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