U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

prkca protein kinase C, alpha [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 780209, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
prkcaprovided by Xenbase
Official Full Name
protein kinase C, alphaprovided by Xenbase
Primary source
Xenbase:XB-GENE-5942870
See related
Ensembl:ENSXETG00000048836
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
XPKCI; pkcalpha; pkc-alpha
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 10
Exon count:
18
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 10 NC_030686.2 (50883607..51003851)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) Unplaced Scaffold NW_016685415.1 (2216..4370, complement)

Chromosome 10 - NC_030686.2Genomic Context describing neighboring genes Neighboring gene axin 2 Neighboring gene centrosomal protein 112kDa Neighboring gene apolipoprotein H Neighboring gene calcium channel, voltage-dependent, gamma subunit 5 Neighboring gene calcium channel, voltage-dependent, gamma subunit 4

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC146825

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables diacylglycerol-dependent serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

Go to the top of the page Help
Preferred Names
protein kinase C alpha type
Names
pkc-like 2
NP_001072752.1
XP_031750036.1
XP_031750037.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079284.1 → NP_001072752.1  protein kinase C alpha type

    See identical proteins and their annotated locations for NP_001072752.1

    Status: PROVISIONAL

    Source sequence(s)
    BC125756
    UniProtKB/TrEMBL
    A0A803JE87, A0JM65
    Related
    ENSXETP00000106188.1, ENSXETT00000116903.1
    Conserved Domains (3) summary
    cd04026
    Location:163 → 293
    C2_PKC_alpha_gamma; C2 domain in Protein Kinase C (PKC) alpha and gamma
    cd05615
    Location:334 → 674
    STKc_cPKC_alpha; Catalytic domain of the Serine/Threonine Kinase, Classical Protein Kinase C alpha
    pfam00130
    Location:41 → 91
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030686.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    50883607..51003851
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031894176.1 → XP_031750036.1  protein kinase C alpha type isoform X1

    UniProtKB/TrEMBL
    A0A803KEL3, A0A8J1IZY1
    Related
    ENSXETP00000118883.1, ENSXETT00000116552.1
    Conserved Domains (4) summary
    cd04026
    Location:163 → 293
    C2_PKC_alpha_gamma; C2 domain in Protein Kinase C (PKC) alpha and gamma
    cd05615
    Location:348 → 688
    STKc_cPKC_alpha; Catalytic domain of the Serine/Threonine Kinase, Classical Protein Kinase C alpha
    cd20833
    Location:39 → 96
    C1_cPKC_rpt1; first protein kinase C conserved region 1 (C1 domain) found in the classical (or conventional) protein kinase C (cPKC) family
    cd20836
    Location:106 → 159
    C1_cPKC_rpt2; second protein kinase C conserved region 1 (C1 domain) found in the classical (or conventional) protein kinase C (cPKC) family

  2. XM_031894177.1 → XP_031750037.1  protein kinase C alpha type isoform X2

    UniProtKB/TrEMBL
    A0A8J1IWQ9
    Conserved Domains (3) summary
    cd04026
    Location:30 → 160
    C2_PKC_alpha_gamma; C2 domain in Protein Kinase C (PKC) alpha and gamma
    cd05615
    Location:215 → 555
    STKc_cPKC_alpha; Catalytic domain of the Serine/Threonine Kinase, Classical Protein Kinase C alpha
    cl00040
    Location:1 → 26
    C1; protein kinase C conserved region 1 (C1 domain) superfamily
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.