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ZNF165 zinc finger protein 165 [ Homo sapiens (human) ]

Gene ID: 7718, updated on 7-Jun-2020

Summary

Official Symbol
ZNF165provided by HGNC
Official Full Name
zinc finger protein 165provided by HGNC
Primary source
HGNC:HGNC:12953
See related
Ensembl:ENSG00000197279 MIM:600834
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT53; LD65; ZSCAN7
Summary
This gene encodes a member of the Kruppel family of zinc finger proteins. Members of this DNA-binding protein family act as transcriptional regulators. This gene is located within a cluster of zinc finger family members. The encoded protein may play a role in spermatogenesis. [provided by RefSeq, Jul 2008]
Expression
Broad expression in testis (RPKM 10.2), placenta (RPKM 2.3) and 15 other tissues See more
Orthologs

Genomic context

See ZNF165 in Genome Data Viewer
Location:
6p22.1
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (28080282..28104244)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (28048482..28057341)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily B member 8 pseudogene Neighboring gene olfactory receptor family 1 subfamily F member 12 Neighboring gene zinc finger and SCAN domain containing 12 pseudogene 1 Neighboring gene zinc finger protein 601, pseudogene Neighboring gene zinc finger protein 602, pseudogene Neighboring gene ZSCAN16 antisense RNA 1 Neighboring gene zinc finger and SCAN domain containing 16

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 165
Names
cancer/testis antigen 53
zinc finger and SCAN domain-containing protein 7

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001376491.1NP_001363420.1  zinc finger protein 165 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-4 all encode the same isoform (a).
    Source sequence(s)
    AL121944
  2. NM_001376492.1NP_001363421.1  zinc finger protein 165 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-4 all encode the same isoform (a).
    Source sequence(s)
    AL121944
  3. NM_001376493.1NP_001363422.1  zinc finger protein 165 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-4 all encode the same isoform (a).
    Source sequence(s)
    AL121944
  4. NM_001376494.1NP_001363423.1  zinc finger protein 165 isoform b

    Status: REVIEWED

    Source sequence(s)
    AL121944
  5. NM_003447.4NP_003438.1  zinc finger protein 165 isoform a

    See identical proteins and their annotated locations for NP_003438.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1-4 all encode the same isoform (a).
    Source sequence(s)
    AL121944, AY083664
    Consensus CDS
    CCDS4643.1
    UniProtKB/Swiss-Prot
    P49910
    UniProtKB/TrEMBL
    Q53Z40
    Related
    ENSP00000366542.1, ENST00000377325.2
    Conserved Domains (3) summary
    smart00431
    Location:45157
    SCAN; leucine rich region
    COG5048
    Location:426479
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:402422
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    28080282..28104244
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017011262.1XP_016866751.1  zinc finger protein 165 isoform X3

  2. XM_017011261.2XP_016866750.1  zinc finger protein 165 isoform X2

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