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ZNF155 zinc finger protein 155 [ Homo sapiens (human) ]

Gene ID: 7711, updated on 2-Oct-2018

Summary

Official Symbol
ZNF155provided by HGNC
Official Full Name
zinc finger protein 155provided by HGNC
Primary source
HGNC:HGNC:12940
See related
Ensembl:ENSG00000204920 MIM:604086; Vega:OTTHUMG00000182215
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
pHZ-96
Expression
Ubiquitous expression in thyroid (RPKM 3.4), adrenal (RPKM 2.6) and 25 other tissues See more
Orthologs

Genomic context

See ZNF155 in Genome Data Viewer
Location:
19q13.31
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 19 NC_000019.10 (43967006..43998326)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (44472014..44502477)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100505715 Neighboring gene zinc finger protein 45 Neighboring gene zinc finger protein 221 Neighboring gene uncharacterized LOC101928063 Neighboring gene zinc finger protein 230 Neighboring gene uncharacterized LOC105372414

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Pathways from BioSystems

  • Gene Expression, organism-specific biosystem (from REACTOME)
    Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
  • Generic Transcription Pathway, organism-specific biosystem (from REACTOME)
    Generic Transcription Pathway, organism-specific biosystemOVERVIEW OF TRANSCRIPTION REGULATION: Detailed studies of gene transcription regulation in a wide variety of eukaryotic systems has revealed the general principles and mechanisms by which cell- or t...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC161655

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA-binding transcription factor activity, RNA polymerase II-specific ISA
Inferred from Sequence Alignment
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 155
Names
KRAB A domain

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001260486.1NP_001247415.1  zinc finger protein 155 isoform 1

    See identical proteins and their annotated locations for NP_001247415.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 encode the same isoform (1).
    Source sequence(s)
    AC006213, BC126377, DA164828, DA504192, DN994146
    Consensus CDS
    CCDS12634.1
    UniProtKB/Swiss-Prot
    Q12901
    Related
    ENSP00000481677.1, ENST00000611002.4
    Conserved Domains (6) summary
    smart00349
    Location:867
    KRAB; krueppel associated box
    COG5048
    Location:202486
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:206226
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:204226
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:218243
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001260487.1NP_001247416.1  zinc finger protein 155 isoform 1

    See identical proteins and their annotated locations for NP_001247416.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 encode the same isoform (1).
    Source sequence(s)
    AC006213, BC126377, DA164828, DC330742, DN994146
    Consensus CDS
    CCDS12634.1
    UniProtKB/Swiss-Prot
    Q12901
    Conserved Domains (6) summary
    smart00349
    Location:867
    KRAB; krueppel associated box
    COG5048
    Location:202486
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:206226
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:204226
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:218243
    zf-H2C2_2; Zinc-finger double domain
  3. NM_001260488.1NP_001247417.1  zinc finger protein 155 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) is longer and has a distinct N-terminus, compared to variant 1.
    Source sequence(s)
    AC006213, AK297360, BC126377, DA164828, DN994146
    Consensus CDS
    CCDS58668.1
    UniProtKB/Swiss-Prot
    Q12901
    Related
    ENSP00000385163.2, OTTHUMP00000268649, ENST00000407951.6, OTTHUMT00000460073
    Conserved Domains (6) summary
    smart00349
    Location:1978
    KRAB; krueppel associated box
    COG5048
    Location:213497
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:217237
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:215237
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:1958
    KRAB; KRAB box
    pfam13465
    Location:229254
    zf-H2C2_2; Zinc-finger double domain
  4. NM_003445.3NP_003436.3  zinc finger protein 155 isoform 1

    See identical proteins and their annotated locations for NP_003436.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the shorter isoform (1). Variants 1, 2, 3 and 4 encode the same isoform.
    Source sequence(s)
    AC006213, AF187986, BC130381, DA111916, DA164828, DN994146
    Consensus CDS
    CCDS12634.1
    UniProtKB/Swiss-Prot
    Q12901
    Related
    ENSP00000465691.1, OTTHUMP00000268651, ENST00000590615.5, OTTHUMT00000460075
    Conserved Domains (6) summary
    smart00349
    Location:867
    KRAB; krueppel associated box
    COG5048
    Location:202486
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:206226
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:204226
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:218243
    zf-H2C2_2; Zinc-finger double domain
  5. NM_198089.2NP_932355.2  zinc finger protein 155 isoform 1

    See identical proteins and their annotated locations for NP_932355.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 encode the same isoform (1).
    Source sequence(s)
    AC006213, AK314510, DA164828, DN994146
    Consensus CDS
    CCDS12634.1
    UniProtKB/Swiss-Prot
    Q12901
    Related
    ENSP00000270014.1, OTTHUMP00000268650, ENST00000270014.6, OTTHUMT00000460074
    Conserved Domains (6) summary
    smart00349
    Location:867
    KRAB; krueppel associated box
    COG5048
    Location:202486
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:206226
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:204226
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:218243
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p12 Primary Assembly

    Range
    43967006..43998326
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011527279.3XP_011525581.1  zinc finger protein 155 isoform X1

    See identical proteins and their annotated locations for XP_011525581.1

    UniProtKB/Swiss-Prot
    Q12901
    Conserved Domains (3) summary
    COG5048
    Location:213497
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:217237
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1959
    KRAB; KRAB box
  2. XM_005259215.4XP_005259272.1  zinc finger protein 155 isoform X2

    See identical proteins and their annotated locations for XP_005259272.1

    UniProtKB/Swiss-Prot
    Q12901
    Conserved Domains (6) summary
    smart00349
    Location:867
    KRAB; krueppel associated box
    COG5048
    Location:202486
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:206226
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:204226
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:218243
    zf-H2C2_2; Zinc-finger double domain
  3. XM_017027248.2XP_016882737.1  zinc finger protein 155 isoform X1

    UniProtKB/Swiss-Prot
    Q12901
    Conserved Domains (3) summary
    COG5048
    Location:213497
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:217237
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1959
    KRAB; KRAB box
  4. XM_011527278.3XP_011525580.1  zinc finger protein 155 isoform X1

    See identical proteins and their annotated locations for XP_011525580.1

    UniProtKB/Swiss-Prot
    Q12901
    Conserved Domains (3) summary
    COG5048
    Location:213497
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:217237
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1959
    KRAB; KRAB box
  5. XM_024451694.1XP_024307462.1  zinc finger protein 155 isoform X1

    Conserved Domains (3) summary
    COG5048
    Location:213497
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:217237
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1959
    KRAB; KRAB box
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