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ZNF132 zinc finger protein 132 [ Homo sapiens (human) ]

Gene ID: 7691, updated on 5-Jan-2022

Summary

Official Symbol
ZNF132provided by HGNC
Official Full Name
zinc finger protein 132provided by HGNC
Primary source
HGNC:HGNC:12916
See related
Ensembl:ENSG00000131849 MIM:604074
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
pHZ-12
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Ubiquitous expression in thyroid (RPKM 3.7), ovary (RPKM 2.5) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF132 in Genome Data Viewer
Location:
19q13.43
Exon count:
3
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (58432814..58440153, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (58944181..58951520, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 2560 Neighboring gene zinc finger protein 584 Neighboring gene zinc finger protein 250 pseudogene Neighboring gene zinc finger protein 324B

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Homology

Clone Names

  • MGC126390, MGC126391

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_003433.4NP_003424.3  zinc finger protein 132

    See identical proteins and their annotated locations for NP_003424.3

    Status: VALIDATED

    Source sequence(s)
    AK057460, BC109107, BQ774411, U09411
    Consensus CDS
    CCDS12980.1
    UniProtKB/Swiss-Prot
    P52740
    UniProtKB/TrEMBL
    B3KQ54
    Related
    ENSP00000254166.2, ENST00000254166.4
    Conserved Domains (3) summary
    COG5048
    Location:105528
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:433453
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:3778
    KRAB; KRAB box

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    58432814..58440153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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