Format

Send to:

Choose Destination

ZNF70 zinc finger protein 70 [ Homo sapiens (human) ]

Gene ID: 7621, updated on 4-Jul-2021

Summary

Official Symbol
ZNF70provided by HGNC
Official Full Name
zinc finger protein 70provided by HGNC
Primary source
HGNC:HGNC:13140
See related
Ensembl:ENSG00000187792 MIM:194544
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Cos17
Expression
Ubiquitous expression in ovary (RPKM 2.8), thyroid (RPKM 1.7) and 24 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See ZNF70 in Genome Data Viewer
Location:
22q11.23
Exon count:
3
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 22 NC_000022.11 (23738682..23751112, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (24080869..24093299, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene GUSB pseudogene 11 Neighboring gene argininosuccinate lyase pseudogene 1 Neighboring gene ral guanine nucleotide dissociation stimulator like 4 Neighboring gene V-set pre-B cell surrogate light chain 3 Neighboring gene chromosome 22 open reading frame 15 Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 10

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ44547, MGC48959

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 70
Names
zinc finger protein N27C7-1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021916.4NP_068735.1  zinc finger protein 70

    See identical proteins and their annotated locations for NP_068735.1

    Status: VALIDATED

    Source sequence(s)
    AK122721, AP000348, BC040161
    Consensus CDS
    CCDS13812.1
    UniProtKB/Swiss-Prot
    Q9UC06
    UniProtKB/TrEMBL
    B3KV76
    Related
    ENSP00000339314.3, ENST00000341976.5
    Conserved Domains (2) summary
    COG5048
    Location:138442
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:310330
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p13 Primary Assembly

    Range
    23738682..23751112 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024452270.1XP_024308038.1  zinc finger protein 70 isoform X1

    Conserved Domains (2) summary
    COG5048
    Location:138442
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:310330
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_024452271.1XP_024308039.1  zinc finger protein 70 isoform X1

    Conserved Domains (2) summary
    COG5048
    Location:138442
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:310330
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_024452269.1XP_024308037.1  zinc finger protein 70 isoform X1

    Conserved Domains (2) summary
    COG5048
    Location:138442
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:310330
    ZF_C2H2; C2H2 Zn finger [structural motif]
Support Center