Format

Send to:

Choose Destination

ZNF23 zinc finger protein 23 [ Homo sapiens (human) ]

Gene ID: 7571, updated on 12-Oct-2019

Summary

Official Symbol
ZNF23provided by HGNC
Official Full Name
zinc finger protein 23provided by HGNC
Primary source
HGNC:HGNC:13023
See related
Ensembl:ENSG00000167377 MIM:194527
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KOX16; ZNF359; ZNF612; Zfp612
Expression
Ubiquitous expression in testis (RPKM 6.2), brain (RPKM 4.4) and 25 other tissues See more
Orthologs

Genomic context

See ZNF23 in Genome Data Viewer
Location:
16q22.2
Exon count:
7
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (71447597..71462247, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (71481500..71496295, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene tRNA-Met (anticodon CAT) 2-1 Neighboring gene TLE family member 7 Neighboring gene zinc finger protein 19 Neighboring gene uncharacterized LOC105371335

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

  • Gene Expression, organism-specific biosystem (from REACTOME)
    Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
  • Generic Transcription Pathway, organism-specific biosystem (from REACTOME)
    Generic Transcription Pathway, organism-specific biosystemOVERVIEW OF TRANSCRIPTION REGULATION: Detailed studies of gene transcription regulation in a wide variety of eukaryotic systems has revealed the general principles and mechanisms by which cell- or t...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: ZNF19

Homology

Clone Names

  • MGC57283

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific NAS
Non-traceable Author Statement
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 23
Names
kruppel-like zinc finger factor X31
zinc finger protein 23 (KOX 16)
zinc finger protein 32
zinc finger protein 359
zinc finger protein 612

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001304492.2NP_001291421.1  zinc finger protein 23 isoform a

    See identical proteins and their annotated locations for NP_001291421.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (a).
    Source sequence(s)
    AK091039, AL080123
    Consensus CDS
    CCDS10900.1
    UniProtKB/Swiss-Prot
    P17027
    UniProtKB/TrEMBL
    B3KR55
    Related
    ENSP00000349796.4, ENST00000357254.8
    Conserved Domains (3) summary
    COG5048
    Location:186606
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:338358
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:131
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  2. NM_001304493.2NP_001291422.1  zinc finger protein 23 isoform b

    See identical proteins and their annotated locations for NP_001291422.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains multiple differences in the 5' region, and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus than isoform a. Variants 3 and 4 encode the same isoform (b).
    Source sequence(s)
    AC010547, AL080123, BC048974, DB160047
    Consensus CDS
    CCDS76895.1
    UniProtKB/Swiss-Prot
    P17027
    Conserved Domains (3) summary
    COG5048
    Location:128548
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:280300
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:461485
    zf-H2C2_2; Zinc-finger double domain
  3. NM_001304494.2NP_001291423.1  zinc finger protein 23 isoform b

    See identical proteins and their annotated locations for NP_001291423.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) contains multiple differences in the 5' region, and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus than isoform a. Variants 3 and 4 encode the same isoform (b).
    Source sequence(s)
    AK297130, AL080123, DB160047
    Consensus CDS
    CCDS76895.1
    UniProtKB/Swiss-Prot
    P17027
    UniProtKB/TrEMBL
    B4DLS2
    Related
    ENSP00000462429.1, ENST00000564528.1
    Conserved Domains (3) summary
    COG5048
    Location:128548
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:280300
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:461485
    zf-H2C2_2; Zinc-finger double domain
  4. NM_145911.3NP_666016.1  zinc finger protein 23 isoform a

    See identical proteins and their annotated locations for NP_666016.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 encode the same isoform (a).
    Source sequence(s)
    AC010547, AL080123, BC007256, DA530642
    Consensus CDS
    CCDS10900.1
    UniProtKB/Swiss-Prot
    P17027
    Related
    ENSP00000377171.2, ENST00000393539.6
    Conserved Domains (3) summary
    COG5048
    Location:186606
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:338358
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:131
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    71447597..71462247 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center