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ZNF23 zinc finger protein 23 [ Homo sapiens (human) ]

Gene ID: 7571, updated on 23-Nov-2021

Summary

Official Symbol
ZNF23provided by HGNC
Official Full Name
zinc finger protein 23provided by HGNC
Primary source
HGNC:HGNC:13023
See related
Ensembl:ENSG00000167377 MIM:194527
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KOX16; ZNF359; ZNF612; Zfp612
Expression
Ubiquitous expression in testis (RPKM 6.2), brain (RPKM 4.4) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF23 in Genome Data Viewer
Location:
16q22.2
Exon count:
8
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (71447597..71462247, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (71481500..71496150, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene tRNA-Met (anticodon CAT) 2-1 Neighboring gene TLE family member 7 Neighboring gene zinc finger protein 19 Neighboring gene uncharacterized LOC105371335

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: ZNF19

Homology

Clone Names

  • MGC57283

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables sequence-specific double-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 23
Names
kruppel-like zinc finger factor X31
zinc finger protein 23 (KOX 16)
zinc finger protein 32
zinc finger protein 359
zinc finger protein 612

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001304492.2NP_001291421.1  zinc finger protein 23 isoform a

    See identical proteins and their annotated locations for NP_001291421.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2), as well as variants 1, 5, and 6, encodes isoform a.
    Source sequence(s)
    AK091039, AL080123
    Consensus CDS
    CCDS10900.1
    UniProtKB/Swiss-Prot
    P17027
    UniProtKB/TrEMBL
    B3KR55
    Related
    ENSP00000349796.4, ENST00000357254.8
    Conserved Domains (3) summary
    COG5048
    Location:186606
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:338358
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:131
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  2. NM_001304493.2NP_001291422.1  zinc finger protein 23 isoform b

    See identical proteins and their annotated locations for NP_001291422.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3), as well as variants 4-12, encodes isoform b.
    Source sequence(s)
    AC010547, AL080123, BC048974, DB160047
    Consensus CDS
    CCDS76895.1
    UniProtKB/Swiss-Prot
    P17027
    Conserved Domains (2) summary
    COG5048
    Location:128548
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:280300
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. NM_001304494.2NP_001291423.1  zinc finger protein 23 isoform b

    See identical proteins and their annotated locations for NP_001291423.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4), as well as variants 3 and 5-12, encodes isoform b.
    Source sequence(s)
    AK297130, AL080123, DB160047
    Consensus CDS
    CCDS76895.1
    UniProtKB/Swiss-Prot
    P17027
    UniProtKB/TrEMBL
    B4DLS2
    Related
    ENSP00000462429.1, ENST00000564528.1
    Conserved Domains (2) summary
    COG5048
    Location:128548
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:280300
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. NM_001381965.1NP_001368894.1  zinc finger protein 23 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5), as well as variants 1, 2, and 6, encodes isoform a.
    Source sequence(s)
    AC010547
    Conserved Domains (3) summary
    COG5048
    Location:186606
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:338358
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:131
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  5. NM_001381966.1NP_001368895.1  zinc finger protein 23 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6), as well as variants 1, 2, and 5, encodes isoform a.
    Source sequence(s)
    AC010547
    Conserved Domains (3) summary
    COG5048
    Location:186606
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:338358
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:131
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  6. NM_001381967.1NP_001368896.1  zinc finger protein 23 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7), as well as variants 3, 4, and 8-12, encodes isoform b.
    Source sequence(s)
    AC010547
    Conserved Domains (2) summary
    COG5048
    Location:128548
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:280300
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. NM_001381968.1NP_001368897.1  zinc finger protein 23 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8), as well as variants 3, 4, 7, and 9-12, encodes isoform b.
    Source sequence(s)
    AC010547
    Conserved Domains (2) summary
    COG5048
    Location:128548
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:280300
    ZF_C2H2; C2H2 Zn finger [structural motif]
  8. NM_001381969.1NP_001368898.1  zinc finger protein 23 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9), as well as variants 3, 4, 7, 8, and 10-12, encodes isoform b.
    Source sequence(s)
    AC010547
    Conserved Domains (2) summary
    COG5048
    Location:128548
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:280300
    ZF_C2H2; C2H2 Zn finger [structural motif]
  9. NM_001381970.1NP_001368899.1  zinc finger protein 23 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10), as well as variants 3, 4, 7-9, 11, and 12, encodes isoform b.
    Source sequence(s)
    AC010547
    Conserved Domains (2) summary
    COG5048
    Location:128548
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:280300
    ZF_C2H2; C2H2 Zn finger [structural motif]
  10. NM_001381971.1NP_001368900.1  zinc finger protein 23 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11), as well as variants 3, 4, 7-10, and 12, encodes isoform b.
    Source sequence(s)
    AC010547
    Conserved Domains (2) summary
    COG5048
    Location:128548
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:280300
    ZF_C2H2; C2H2 Zn finger [structural motif]
  11. NM_001381972.1NP_001368901.1  zinc finger protein 23 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (12), as well as variants 3, 4, and 7-11, encodes isoform b.
    Source sequence(s)
    AC010547
    Conserved Domains (2) summary
    COG5048
    Location:128548
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:280300
    ZF_C2H2; C2H2 Zn finger [structural motif]
  12. NM_001381973.1NP_001368902.1  zinc finger protein 23 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (13), as well as variant 14, encodes isoform c.
    Source sequence(s)
    AC010547
    Conserved Domains (3) summary
    smart00349
    Location:1069
    KRAB; krueppel associated box
    COG5048
    Location:225645
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:377397
    ZF_C2H2; C2H2 Zn finger [structural motif]
  13. NM_001381974.1NP_001368903.1  zinc finger protein 23 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (14), as well as variant 13, encodes isoform c.
    Source sequence(s)
    AC010547
    Conserved Domains (3) summary
    smart00349
    Location:1069
    KRAB; krueppel associated box
    COG5048
    Location:225645
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:377397
    ZF_C2H2; C2H2 Zn finger [structural motif]
  14. NM_001381975.1NP_001368904.1  zinc finger protein 23 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (15), as well as variants 16-19, encodes isoform d.
    Source sequence(s)
    AC010547
    Conserved Domains (3) summary
    COG5048
    Location:187607
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:339359
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:131
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  15. NM_001381976.1NP_001368905.1  zinc finger protein 23 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (16), as well as variants 15 and 17-19, encodes isoform d.
    Source sequence(s)
    AC010547
    Conserved Domains (3) summary
    COG5048
    Location:187607
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:339359
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:131
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  16. NM_001381977.1NP_001368906.1  zinc finger protein 23 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (17), as well as variants 15, 16, 18, and 19, encodes isoform d.
    Source sequence(s)
    AC010547
    Conserved Domains (3) summary
    COG5048
    Location:187607
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:339359
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:131
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  17. NM_001381978.1NP_001368907.1  zinc finger protein 23 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (18), as well as variants 15-17 and 19, encodes isoform d.
    Source sequence(s)
    AC010547
    Conserved Domains (3) summary
    COG5048
    Location:187607
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:339359
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:131
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  18. NM_001381979.1NP_001368908.1  zinc finger protein 23 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (19), as well as variants 15-18, encodes isoform d.
    Source sequence(s)
    AC010547
    Conserved Domains (3) summary
    COG5048
    Location:187607
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:339359
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:131
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  19. NM_001381980.1NP_001368909.1  zinc finger protein 23 isoform e

    Status: VALIDATED

    Source sequence(s)
    AC010547
    Conserved Domains (3) summary
    smart00349
    Location:1069
    KRAB; krueppel associated box
    COG5048
    Location:224644
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:376396
    ZF_C2H2; C2H2 Zn finger [structural motif]
  20. NM_001381981.1NP_001368910.1  zinc finger protein 23 isoform f

    Status: VALIDATED

    Source sequence(s)
    AC010547
    Conserved Domains (3) summary
    COG5048
    Location:190610
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:342362
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:131
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  21. NM_001381984.1NP_001368913.1  zinc finger protein 23 isoform g

    Status: VALIDATED

    Description
    Transcript Variant: This variant (22) encodes the longest isoform (g).
    Source sequence(s)
    AC010547
    Related
    ENSP00000497736.1, ENST00000647773.1
    Conserved Domains (3) summary
    smart00349
    Location:1473
    KRAB; krueppel associated box
    COG5048
    Location:229649
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:381401
    ZF_C2H2; C2H2 Zn finger [structural motif]
  22. NM_145911.3NP_666016.1  zinc finger protein 23 isoform a

    See identical proteins and their annotated locations for NP_666016.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1), as well as variants 2, 5, and 6, encodes isoform a.
    Source sequence(s)
    AC010547, AL080123, BC007256, DA530642
    Consensus CDS
    CCDS10900.1
    UniProtKB/Swiss-Prot
    P17027
    Related
    ENSP00000377171.2, ENST00000393539.6
    Conserved Domains (3) summary
    COG5048
    Location:186606
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:338358
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:131
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    71447597..71462247 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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