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ZNF22 zinc finger protein 22 [ Homo sapiens (human) ]

Gene ID: 7570, updated on 13-Mar-2020

Summary

Official Symbol
ZNF22provided by HGNC
Official Full Name
zinc finger protein 22provided by HGNC
Primary source
HGNC:HGNC:13012
See related
Ensembl:ENSG00000165512 MIM:194529
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KOX15; HKR-T1; ZNF422; Zfp422
Expression
Ubiquitous expression in placenta (RPKM 19.3), lymph node (RPKM 18.4) and 25 other tissues See more
Orthologs

Genomic context

See ZNF22 in Genome Data Viewer
Location:
10q11.21
Exon count:
2
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (45000923..45005326)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (45496273..45500777)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene Ras association domain family member 4 Neighboring gene Sharpr-MPRA regulatory region 8316 Neighboring gene DEPP1 autophagy regulator Neighboring gene ZNF22 antisense RNA 1 Neighboring gene double homeobox A pseudogene 4 Neighboring gene centrosomal protein 164 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
zinc ion binding TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
odontogenesis NAS
Non-traceable Author Statement
more info
PubMed 
regulation of transcription, DNA-templated NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
zinc finger protein 22
Names
krox-26 protein
zinc finger protein 22 (KOX 15)
zinc finger protein KOX15
zinc finger protein Krox-26

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_006963.5NP_008894.2  zinc finger protein 22

    See identical proteins and their annotated locations for NP_008894.2

    Status: VALIDATED

    Source sequence(s)
    AL353801, AU310379, BC041139
    Consensus CDS
    CCDS7211.1
    UniProtKB/Swiss-Prot
    P17026
    UniProtKB/TrEMBL
    A0A024R7T4
    Related
    ENSP00000298299.3, ENST00000298299.4
    Conserved Domains (2) summary
    COG5048
    Location:41194
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:113133
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    45000923..45005326
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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