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ZNF20 zinc finger protein 20 [ Homo sapiens (human) ]

Gene ID: 7568, updated on 8-Jul-2018
Official Symbol
ZNF20provided by HGNC
Official Full Name
zinc finger protein 20provided by HGNC
Primary source
HGNC:HGNC:12992
See related
Ensembl:ENSG00000132010 MIM:194557; Vega:OTTHUMG00000156409
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KOX13
Expression
Broad expression in testis (RPKM 5.4), thyroid (RPKM 2.3) and 24 other tissues See more
Orthologs
See ZNF20 in Genome Data Viewer
Location:
19p13.2
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 19 NC_000019.10 (12131350..12140407, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (12242165..12251222, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger family member 788, pseudogene Neighboring gene ribosomal L24 domain containing 1 pseudogene 8 Neighboring gene RNA, 5S ribosomal pseudogene 467 Neighboring gene uncharacterized LOC105372275 Neighboring gene ZNF625-ZNF20 readthrough (NMD candidate) Neighboring gene ribosomal protein L17 pseudogene 47 Neighboring gene zinc finger protein 625

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016
  • Gene Expression, organism-specific biosystem (from REACTOME)
    Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
  • Generic Transcription Pathway, organism-specific biosystem (from REACTOME)
    Generic Transcription Pathway, organism-specific biosystemOVERVIEW OF TRANSCRIPTION REGULATION: Detailed studies of gene transcription regulation in a wide variety of eukaryotic systems has revealed the general principles and mechanisms by which cell- or t...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Clone Names

  • FLJ39241

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II transcription factor activity, sequence-specific DNA binding ISA
Inferred from Sequence Alignment
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
zinc finger protein 20
Names
zinc finger protein KOX13

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001203250.1NP_001190179.1  zinc finger protein 20 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1.
    Source sequence(s)
    AC022415, BM142273, DB034821, DB057678
    Conserved Domains (6) summary
    smart00349
    Location:444
    KRAB; krueppel associated box
    COG5048
    Location:112522
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:394414
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:198218
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:443
    KRAB; KRAB box
    pfam13465
    Location:406431
    zf-H2C2_2; Zinc-finger double domain
  2. NM_021143.3NP_066966.2  zinc finger protein 20 isoform 1

    See identical proteins and their annotated locations for NP_066966.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC022415, BC036714, BM142273, DB057678
    Consensus CDS
    CCDS45986.1
    UniProtKB/Swiss-Prot
    P17024
    Related
    ENSP00000335437.5, OTTHUMP00000209846, ENST00000334213.9, OTTHUMT00000344101
    Conserved Domains (6) summary
    smart00349
    Location:747
    KRAB; krueppel associated box
    COG5048
    Location:115525
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:397417
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:201221
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:746
    KRAB; KRAB box
    pfam13465
    Location:409434
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p12 Primary Assembly

    Range
    12131350..12140407 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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