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CASP6 caspase 6 [ Pan troglodytes (chimpanzee) ]

Gene ID: 736606, updated on 17-Aug-2024

Summary

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Official Symbol
CASP6provided by VGNC
Official Full Name
caspase 6provided by VGNC
Primary source
VGNC:VGNC:58511
Locus tag
CK820_G0024090
See related
Ensembl:ENSPTRG00000046752
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See CASP6 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 3 NC_072401.2 (111141759..111163614, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 4 NC_072402.1 (111141733..111163656, complement)

Chromosome 3 - NC_072401.2Genomic Context describing neighboring genes Neighboring gene mitochondrial calcium uniporter dominant negative subunit beta Neighboring gene uncharacterized LOC134809906 Neighboring gene uncharacterized LOC107974369 Neighboring gene HIG1 hypoxia inducible domain family member 1A pseudogene Neighboring gene phospholipase A2 group XIIA Neighboring gene complement factor I Neighboring gene GAR1 ribonucleoprotein Neighboring gene retinal pigment epithelium-derived rhodopsin homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity involved in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of neuron apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
caspase-6
Names
caspase 6, apoptosis-related cysteine peptidase
XP_016807502.1
XP_016807507.1
XP_016807508.1
XP_063665798.1
XP_063665799.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072401.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    111141759..111163614 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016952018.4 → XP_016807507.1  caspase-6 isoform X3

  2. XM_063809728.1 → XP_063665798.1  caspase-6 isoform X2

  3. XM_016952013.4 → XP_016807502.1  caspase-6 isoform X1

    UniProtKB/TrEMBL
    A0A2J8M2C8, A0A6D2XYB7, K7B3Z2
    Related
    ENSPTRP00000080795.1
    Conserved Domains (1) summary
    smart00115
    Location:37 → 290
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues

  4. XM_016952019.4 → XP_016807508.1  caspase-6 isoform X4

    UniProtKB/TrEMBL
    A0A2I3RZ85, A0A2J8M2E0, A0A6D2Y514
    Related
    ENSPTRP00000069930.1
    Conserved Domains (1) summary
    cd00032
    Location:14 → 200
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

  5. XM_063809729.1 → XP_063665799.1  caspase-6 isoform X3

Nucleotide Protein
Heading Accession and Version

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