INPPL1 inositol polyphosphate phosphatase like 1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: INPPL1provided by VGNC
Official Full Name: inositol polyphosphate phosphatase like 1provided by VGNC
Primary source: VGNC:VGNC:73752
See related: Ensembl:ENSMMUG00000010451
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 29

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	14	NC_041767.1 (65196068..65210420)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	14	NC_027906.1 (64164807..64179151)

Chromosome 14 - NC_041767.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH67903 (e-PCR)
- UniSTS:79363

INPPL1 (e-PCR)
- UniSTS:40458

D11S4140 (e-PCR)
- UniSTS:473375

INPPL1__6468 (e-PCR)
- UniSTS:464501

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in phosphatidylinositol dephosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

Names: phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2

NP_001247768.1

EC 3.1.3.56

XP_014970616.2

EC 3.1.3.56

XP_014970617.2

EC 3.1.3.56

XP_028688685.1

EC 3.1.3.56

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001260839.1 → NP_001247768.1 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

See identical proteins and their annotated locations for NP_001247768.1

Status: PROVISIONAL

Source sequence(s)

JU475481

UniProtKB/TrEMBL

A0A1D5Q071, H9F5V6, H9Z8L9

Related

ENSMMUP00000041433.2, ENSMMUT00000062600.2

Conserved Domains (4) summary

cd09491
Location:1194 → 1256

SAM_Ship2; SAM domain of Ship2 lipid phosphatase proteins

cd09101
Location:424 → 727

INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins

smart00454
Location:1202 → 1258

SAM; Sterile alpha motif

cd10343
Location:17 → 119

SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041767.1 Reference Mmul_10 Primary Assembly

Range

65196068..65210420

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015115130.2 → XP_014970616.2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1

UniProtKB/TrEMBL

F7CRA7, H9F5V6

Related

ENSMMUP00000013695.4, ENSMMUT00000014619.4

Conserved Domains (4) summary

cd09491
Location:1251 → 1313

SAM_Ship2; SAM domain of Ship2 lipid phosphatase proteins

cd09101
Location:481 → 784

INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins

pfam15685
Location:959 → 1103

GGN; Gametogenetin

cl15255
Location:17 → 176

SH2; Src homology 2 (SH2) domain
XM_015115131.2 → XP_014970617.2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X3

UniProtKB/TrEMBL

H9F5V6

Conserved Domains (3) summary

cd09101
Location:481 → 784

INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins

pfam15685
Location:959 → 1103

GGN; Gametogenetin

cl15255
Location:17 → 176

SH2; Src homology 2 (SH2) domain
XM_028832852.1 → XP_028688685.1 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X2

UniProtKB/TrEMBL

G7NE91

Conserved Domains (4) summary

cd09491
Location:1184 → 1246

SAM_Ship2; SAM domain of Ship2 lipid phosphatase proteins

cd09101
Location:414 → 717

INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins

pfam15685
Location:892 → 1036

GGN; Gametogenetin

cl15255
Location:52 → 109

SH2; Src homology 2 (SH2) domain