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Iqcg IQ motif containing G [ Mus musculus (house mouse) ]

Gene ID: 69707, updated on 8-Dec-2022

Summary

Official Symbol
Iqcgprovided by MGI
Official Full Name
IQ motif containing Gprovided by MGI
Primary source
MGI:MGI:1916957
See related
Ensembl:ENSMUSG00000035578 AllianceGenome:MGI:1916957
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
repro1; esgd12d; G1-374-12; stubby12d; 2400003L07Rik
Summary
Enables calmodulin binding activity. Involved in sperm axoneme assembly. Located in cytosol; manchette; and sperm flagellum. Is expressed in brain; lung epithelium; and nose. Orthologous to human IQCG (IQ motif containing G). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in limb E14.5 (RPKM 5.8), testis adult (RPKM 5.5) and 28 other tissues See more
Orthologs
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Genomic context

See Iqcg in Genome Data Viewer
Location:
16; 16 B3
Exon count:
13
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (32834640..32876617, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (33014270..33057145, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene leucine-rich repeats and calponin homology (CH) domain containing 3 Neighboring gene predicted gene 6611 Neighboring gene nuclear encoded rRNA 5S 33 Neighboring gene ribosomal protein L35A Neighboring gene leishmanolysin-like (metallopeptidase M8 family) Neighboring gene microRNA 1947

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables Hsp70 protein binding ISO
Inferred from Sequence Orthology
more info
 
enables calmodulin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables calmodulin binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in cilium organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in sperm axoneme assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in sperm axoneme assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within spermatid development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in spermatid development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cilium IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in manchette IDA
Inferred from Direct Assay
more info
PubMed 
located_in motile cilium IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in sperm flagellum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in sperm flagellum IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
dynein regulatory complex protein 9
Names
IQ domain-containing protein G

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178378.3NP_848465.1  dynein regulatory complex protein 9

    See identical proteins and their annotated locations for NP_848465.1

    Status: VALIDATED

    Source sequence(s)
    AC126023, BC049990, BY120455
    Consensus CDS
    CCDS37316.1
    UniProtKB/Swiss-Prot
    Q80W32
    Related
    ENSMUSP00000110752.2, ENSMUST00000115100.9
    Conserved Domains (1) summary
    pfam04111
    Location:202343
    APG6; Autophagy protein Apg6

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    32834640..32876617 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006522519.5XP_006522582.1  dynein regulatory complex protein 9 isoform X2

    Conserved Domains (1) summary
    pfam04111
    Location:139280
    APG6; Autophagy protein Apg6
  2. XM_011246004.4XP_011244306.1  dynein regulatory complex protein 9 isoform X1

    See identical proteins and their annotated locations for XP_011244306.1

    UniProtKB/Swiss-Prot
    Q80W32
    Conserved Domains (1) summary
    pfam04111
    Location:202343
    APG6; Autophagy protein Apg6
  3. XM_006522520.5XP_006522583.1  dynein regulatory complex protein 9 isoform X3

    See identical proteins and their annotated locations for XP_006522583.1

    Conserved Domains (1) summary
    pfam04111
    Location:69210
    APG6; Autophagy protein Apg6