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NOS2 nitric oxide synthase 2 [ Meleagris gallopavo (turkey) ]

Gene ID: 692136, updated on 5-Mar-2024

Summary

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Gene symbol
NOS2
Gene description
nitric oxide synthase 2
See related
Ensembl:ENSMGAG00000008503
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Meleagris gallopavo
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Meleagridinae; Meleagris
Also known as
INOS
Orthologs
human mouse all
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Genomic context

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See NOS2 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
31
Annotation release Status Assembly Chr Location
103 current Turkey_5.1 (GCF_000146605.3) 21 NC_015031.2 (6378494..6412200, complement)
Build 1.1 previous assembly Turkey_2.01 (GCF_000146605.1) 21 NC_015031.1 (9606356..9622710, complement)

Chromosome 21 - NC_015031.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104913909 Neighboring gene kinase suppressor of ras 1 Neighboring gene uncharacterized LOC109370662 Neighboring gene WD repeat and SOCS box containing 1 Neighboring gene WD repeat and SOCS box-containing protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of turkey inducible nitric oxide synthase and identification of its expression in the intestinal epithelium following astrovirus infection. Meyerhoff RR, et al. Comp Immunol Microbiol Infect Dis, 2012 Jan. PMID 22118854, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables FMN binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables NADP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nitric-oxide synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nitric oxide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
nitric oxide synthase, inducible
Names
inducible nitric oxide synthase
NP_001290142.1
XP_003211919.2
XP_010720283.1
XP_010720284.1
XP_010720285.1
XP_031412252.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001303213.1 → NP_001290142.1  nitric oxide synthase, inducible

    See identical proteins and their annotated locations for NP_001290142.1

    Status: PROVISIONAL

    Source sequence(s)
    GQ184820
    UniProtKB/TrEMBL
    H6S058
    Related
    ENSMGAP00000008733.3, ENSMGAT00000009536.3
    Conserved Domains (4) summary
    cd06202
    Location:733 → 1129
    Nitric_oxide_synthase; The ferredoxin-reductase (FNR) like C-terminal domain of the nitric oxide synthase (NOS) fuses with a heme-containing N-terminal oxidase domain. The reductase portion is similar in structure to NADPH dependent cytochrome-450 reductase (CYPOR), having an ...
    COG0369
    Location:534 → 1124
    CysJ; Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]
    cd00795
    Location:81 → 493
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    pfam00258
    Location:538 → 669
    Flavodoxin_1; Flavodoxin

RefSeqs of Annotated Genomes: Meleagris gallopavo Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Turkey_5.1 Primary Assembly

Genomic

  1. NC_015031.2 Reference Turkey_5.1 Primary Assembly

    Range
    6378494..6412200 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003211871.4 → XP_003211919.2  nitric oxide synthase, inducible isoform X1

    See identical proteins and their annotated locations for XP_003211919.2

    UniProtKB/TrEMBL
    G1N8R3
    Conserved Domains (3) summary
    cd06202
    Location:733 → 1129
    Nitric_oxide_synthase; The ferredoxin-reductase (FNR) like C-terminal domain of the nitric oxide synthase (NOS) fuses with a heme-containing N-terminal oxidase domain. The reductase portion is similar in structure to NADPH dependent cytochrome-450 reductase (CYPOR), having an ...
    cd00795
    Location:81 → 493
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    pfam00258
    Location:538 → 669
    Flavodoxin_1

  2. XM_010721982.3 → XP_010720284.1  nitric oxide synthase, inducible isoform X1

    See identical proteins and their annotated locations for XP_010720284.1

    UniProtKB/TrEMBL
    G1N8R3
    Conserved Domains (3) summary
    cd06202
    Location:733 → 1129
    Nitric_oxide_synthase; The ferredoxin-reductase (FNR) like C-terminal domain of the nitric oxide synthase (NOS) fuses with a heme-containing N-terminal oxidase domain. The reductase portion is similar in structure to NADPH dependent cytochrome-450 reductase (CYPOR), having an ...
    cd00795
    Location:81 → 493
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    pfam00258
    Location:538 → 669
    Flavodoxin_1

  3. XM_010721981.3 → XP_010720283.1  nitric oxide synthase, inducible isoform X1

    See identical proteins and their annotated locations for XP_010720283.1

    UniProtKB/TrEMBL
    G1N8R3
    Conserved Domains (3) summary
    cd06202
    Location:733 → 1129
    Nitric_oxide_synthase; The ferredoxin-reductase (FNR) like C-terminal domain of the nitric oxide synthase (NOS) fuses with a heme-containing N-terminal oxidase domain. The reductase portion is similar in structure to NADPH dependent cytochrome-450 reductase (CYPOR), having an ...
    cd00795
    Location:81 → 493
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    pfam00258
    Location:538 → 669
    Flavodoxin_1

  4. XM_010721983.3 → XP_010720285.1  nitric oxide synthase, inducible isoform X1

    See identical proteins and their annotated locations for XP_010720285.1

    UniProtKB/TrEMBL
    G1N8R3
    Conserved Domains (3) summary
    cd06202
    Location:733 → 1129
    Nitric_oxide_synthase; The ferredoxin-reductase (FNR) like C-terminal domain of the nitric oxide synthase (NOS) fuses with a heme-containing N-terminal oxidase domain. The reductase portion is similar in structure to NADPH dependent cytochrome-450 reductase (CYPOR), having an ...
    cd00795
    Location:81 → 493
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    pfam00258
    Location:538 → 669
    Flavodoxin_1

  5. XM_031556392.1 → XP_031412252.1  nitric oxide synthase, inducible isoform X1

    UniProtKB/TrEMBL
    G1N8R3
    Conserved Domains (3) summary
    cd06202
    Location:733 → 1129
    Nitric_oxide_synthase; The ferredoxin-reductase (FNR) like C-terminal domain of the nitric oxide synthase (NOS) fuses with a heme-containing N-terminal oxidase domain. The reductase portion is similar in structure to NADPH dependent cytochrome-450 reductase (CYPOR), having an ...
    cd00795
    Location:81 → 493
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    pfam00258
    Location:538 → 669
    Flavodoxin_1
Nucleotide Protein
Heading Accession and Version

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