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Rreb1 ras responsive element binding protein 1 [ Mus musculus (house mouse) ]

Gene ID: 68750, updated on 2-Nov-2024

Summary

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Official Symbol
Rreb1provided by MGI
Official Full Name
ras responsive element binding protein 1provided by MGI
Primary source
MGI:MGI:2443664
See related
Ensembl:ENSMUSG00000039087 AllianceGenome:MGI:2443664
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
sao; 1110037N09Rik; B930013M22Rik
Summary
Enables DNA-binding transcription factor activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of brown fat cell differentiation. Acts upstream of or within negative regulation of DNA-templated transcription. Predicted to be located in fibrillar center and nuclear speck. Predicted to be active in nucleus. Is expressed in alimentary system; central nervous system; and genitourinary system. Used to study RASopathy. Orthologous to human RREB1 (ras responsive element binding protein 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in adrenal adult (RPKM 5.6), colon adult (RPKM 5.2) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Rreb1 in Genome Data Viewer
Location:
13 A3.3; 13
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (37962362..38135981)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (37778382..37952005)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_34225 Neighboring gene predicted gene, 40918 Neighboring gene STARR-seq mESC enhancer starr_34227 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:37870871-37870980 Neighboring gene predicted gene, 31600 Neighboring gene STARR-positive B cell enhancer mm9_chr13:37884809-37885110 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:37893604-37893840 Neighboring gene predicted gene, 46411 Neighboring gene STARR-positive B cell enhancer ABC_E1461 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:37972487-37972670 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:37974410-37974611 Neighboring gene STARR-seq mESC enhancer starr_34234 Neighboring gene STARR-positive B cell enhancer ABC_E11541 Neighboring gene STARR-positive B cell enhancer ABC_E7227 Neighboring gene STARR-positive B cell enhancer ABC_E10789 Neighboring gene predicted gene, 52041 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:38086110-38086293 Neighboring gene signal sequence receptor, alpha Neighboring gene STARR-positive B cell enhancer ABC_E9396 Neighboring gene cancer antigen 1 Neighboring gene RIO kinase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Rreb1 is a key transcription factor in Sertoli cell maturation and function and spermatogenesis in mouse. Wu Z, et al. Zygote, 2024 Apr. PMID 38248872
  2. Ras signaling and RREB1 are required for the dissociation of medial edge epithelial cells in murine palatogenesis. Inubushi T, et al. Dis Model Mech, 2022 Feb 1. PMID 34897389, Free PMC Article
  3. Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes. Kent OA, et al. Nat Commun, 2020 Sep 16. PMID 32938917, Free PMC Article
  4. Transcriptional activation of the cholecystokinin gene by DJ-1 through interaction of DJ-1 with RREB1 and the effect of DJ-1 on the cholecystokinin level in mice. Yamane T, et al. PLoS One, 2013. PMID 24348900, Free PMC Article
  5. TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1. Su J, et al. Nature, 2020 Jan. PMID 31915377, Free PMC Article

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Rreb1 is a key transcription factor in Sertoli cell maturation and function and spermatogenesis in mouse.
    Title: Rreb1 is a key transcription factor in Sertoli cell maturation and function and spermatogenesis in mouse.
  2. RREB1 regulates neuronal proteostasis and the microtubule network.
    Title: RREB1 regulates neuronal proteostasis and the microtubule network.
  3. Ras signaling and RREB1 are required for the dissociation of medial edge epithelial cells in murine palatogenesis.
    Title: Ras signaling and RREB1 are required for the dissociation of medial edge epithelial cells in murine palatogenesis.
  4. The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos.
    Title: The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos.
  5. Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes.
    Title: Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes.
  6. identification of RAS-responsive element binding protein 1 (RREB1), a RAS transcriptional effector, as a key partner of TGF-beta-activated SMAD transcription factors in epithelial-to-mesenchymal transitions
    Title: TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (6)  1 citation
  • Spontaneous (1) 
  • Targeted (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription activator activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
  
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of brown fat cell differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of epithelial cell migration IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of epithelial cell migration ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of lamellipodium morphogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of lamellipodium morphogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of mammary gland epithelial cell proliferation IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of mammary gland epithelial cell proliferation ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of substrate adhesion-dependent cell spreading IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of substrate adhesion-dependent cell spreading ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of wound healing, spreading of epidermal cells IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of wound healing, spreading of epidermal cells ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in fibrillar center IEA
Inferred from Electronic Annotation
more info
  
located_in fibrillar center ISO
Inferred from Sequence Orthology
more info
  
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
  
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ras-responsive element-binding protein 1
Names
RAS-responsive zinc finger transcription factor RREB

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039188.2 → NP_001034277.1  ras-responsive element-binding protein 1 isoform 1

    See identical proteins and their annotated locations for NP_001034277.1

    Status: VALIDATED

    Source sequence(s)
    AC022682, CT010477
    Consensus CDS
    CCDS36634.1
    UniProtKB/Swiss-Prot
    Q3UH06
    Related
    ENSMUSP00000105866.3, ENSMUST00000110237.9
    Conserved Domains (3) summary
    COG5048
    Location:64 → 244
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:68 → 88
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:111 → 136
    zf-H2C2_2; Zinc-finger double domain

  2. NM_001177868.2 → NP_001171339.1  ras-responsive element-binding protein 1 isoform 1

    See identical proteins and their annotated locations for NP_001171339.1

    Status: VALIDATED

    Source sequence(s)
    AC022682, CT010477
    Consensus CDS
    CCDS36634.1
    UniProtKB/Swiss-Prot
    Q3UH06
    Related
    ENSMUSP00000121211.2, ENSMUST00000149745.8
    Conserved Domains (3) summary
    COG5048
    Location:64 → 244
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:68 → 88
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:111 → 136
    zf-H2C2_2; Zinc-finger double domain

  3. NM_001177869.2 → NP_001171340.1  ras-responsive element-binding protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001171340.1

    Status: VALIDATED

    Source sequence(s)
    AC022682, CT010477
    Consensus CDS
    CCDS49238.1
    UniProtKB/Swiss-Prot
    Q3UH06
    Conserved Domains (8) summary
    smart00355
    Location:1253 → 1273
    ZnF_C2H2; zinc finger
    COG5048
    Location:64 → 244
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:68 → 88
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:1602 → 1624
    zf-C2H2; Zinc finger, C2H2 type
    pfam04625
    Location:381 → 672
    DEC-1_N; DEC-1 protein, N-terminal region
    pfam13465
    Location:1588 → 1612
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:669 → 693
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam13912
    Location:1575 → 1596
    zf-C2H2_6; C2H2-type zinc finger

  4. NM_001404757.1 → NP_001391686.1  ras-responsive element-binding protein 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022682, CT010477
    UniProtKB/Swiss-Prot
    B8JJE2, B8JJE3, Q3TB97, Q3UH06, Q4ZE88, Q66JZ8

  5. NM_001404758.1 → NP_001391687.1  ras-responsive element-binding protein 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022682, CT010477
    UniProtKB/Swiss-Prot
    B8JJE2, B8JJE3, Q3TB97, Q3UH06, Q4ZE88, Q66JZ8

  6. NM_001404759.1 → NP_001391688.1  ras-responsive element-binding protein 1 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC022682, CT010477

  7. NM_001404760.1 → NP_001391689.1  ras-responsive element-binding protein 1 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC022682, CT010477

  8. NM_026830.3 → NP_081106.1  ras-responsive element-binding protein 1 isoform 1

    See identical proteins and their annotated locations for NP_081106.1

    Status: VALIDATED

    Source sequence(s)
    AC022682, CT010477
    Consensus CDS
    CCDS36634.1
    UniProtKB/Swiss-Prot
    Q3UH06
    Related
    ENSMUSP00000105867.3, ENSMUST00000110238.10
    Conserved Domains (3) summary
    COG5048
    Location:64 → 244
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:68 → 88
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:111 → 136
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. NR_033218.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    CT010477
    Related
    ENSMUST00000124268.8

  2. NR_033615.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC022682, CT010477

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    37962362..38135981
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006516757.5 → XP_006516820.1  ras-responsive element-binding protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006516820.1

    UniProtKB/Swiss-Prot
    Q3UH06
    Conserved Domains (8) summary
    smart00355
    Location:1253 → 1273
    ZnF_C2H2; zinc finger
    COG5048
    Location:64 → 244
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:68 → 88
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:1602 → 1624
    zf-C2H2; Zinc finger, C2H2 type
    pfam04625
    Location:381 → 672
    DEC-1_N; DEC-1 protein, N-terminal region
    pfam13465
    Location:1588 → 1612
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:669 → 693
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam13912
    Location:1575 → 1596
    zf-C2H2_6; C2H2-type zinc finger

  2. XM_030247397.2 → XP_030103257.1  ras-responsive element-binding protein 1 isoform X4

    Conserved Domains (8) summary
    smart00355
    Location:1171 → 1191
    ZnF_C2H2; zinc finger
    sd00017
    Location:17 → 37
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:1520 → 1542
    zf-C2H2; Zinc finger, C2H2 type
    pfam04625
    Location:299 → 590
    DEC-1_N; DEC-1 protein, N-terminal region
    pfam13465
    Location:1506 → 1530
    zf-H2C2_2; Zinc-finger double domain
    pfam13894
    Location:124 → 146
    zf-C2H2_4; C2H2-type zinc finger
    pfam13909
    Location:587 → 611
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam13912
    Location:1493 → 1514
    zf-C2H2_6; C2H2-type zinc finger

  3. XM_006516754.5 → XP_006516817.1  ras-responsive element-binding protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006516817.1

    UniProtKB/Swiss-Prot
    Q3UH06
    Conserved Domains (8) summary
    smart00355
    Location:1253 → 1273
    ZnF_C2H2; zinc finger
    COG5048
    Location:64 → 244
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:68 → 88
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:1602 → 1624
    zf-C2H2; Zinc finger, C2H2 type
    pfam04625
    Location:381 → 672
    DEC-1_N; DEC-1 protein, N-terminal region
    pfam13465
    Location:1588 → 1612
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:669 → 693
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam13912
    Location:1575 → 1596
    zf-C2H2_6; C2H2-type zinc finger

  4. XM_030247395.2 → XP_030103255.1  ras-responsive element-binding protein 1 isoform X4

    Conserved Domains (8) summary
    smart00355
    Location:1171 → 1191
    ZnF_C2H2; zinc finger
    sd00017
    Location:17 → 37
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:1520 → 1542
    zf-C2H2; Zinc finger, C2H2 type
    pfam04625
    Location:299 → 590
    DEC-1_N; DEC-1 protein, N-terminal region
    pfam13465
    Location:1506 → 1530
    zf-H2C2_2; Zinc-finger double domain
    pfam13894
    Location:124 → 146
    zf-C2H2_4; C2H2-type zinc finger
    pfam13909
    Location:587 → 611
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam13912
    Location:1493 → 1514
    zf-C2H2_6; C2H2-type zinc finger

  5. XM_030247396.2 → XP_030103256.1  ras-responsive element-binding protein 1 isoform X4

    Conserved Domains (8) summary
    smart00355
    Location:1171 → 1191
    ZnF_C2H2; zinc finger
    sd00017
    Location:17 → 37
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:1520 → 1542
    zf-C2H2; Zinc finger, C2H2 type
    pfam04625
    Location:299 → 590
    DEC-1_N; DEC-1 protein, N-terminal region
    pfam13465
    Location:1506 → 1530
    zf-H2C2_2; Zinc-finger double domain
    pfam13894
    Location:124 → 146
    zf-C2H2_4; C2H2-type zinc finger
    pfam13909
    Location:587 → 611
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam13912
    Location:1493 → 1514
    zf-C2H2_6; C2H2-type zinc finger

  6. XM_006516749.3 → XP_006516812.1  ras-responsive element-binding protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006516812.1

    UniProtKB/Swiss-Prot
    Q3UH06
    Related
    ENSMUSP00000115599.2, ENSMUST00000128570.9
    Conserved Domains (8) summary
    smart00355
    Location:1253 → 1273
    ZnF_C2H2; zinc finger
    COG5048
    Location:64 → 244
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:68 → 88
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:1602 → 1624
    zf-C2H2; Zinc finger, C2H2 type
    pfam04625
    Location:381 → 672
    DEC-1_N; DEC-1 protein, N-terminal region
    pfam13465
    Location:1588 → 1612
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:669 → 693
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam13912
    Location:1575 → 1596
    zf-C2H2_6; C2H2-type zinc finger

  7. XM_006516758.3 → XP_006516821.1  ras-responsive element-binding protein 1 isoform X2

    Conserved Domains (8) summary
    smart00355
    Location:1253 → 1273
    ZnF_C2H2; zinc finger
    COG5048
    Location:64 → 244
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:68 → 88
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:1551 → 1571
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:1549 → 1571
    zf-C2H2; Zinc finger, C2H2 type
    pfam04625
    Location:381 → 672
    DEC-1_N; DEC-1 protein, N-terminal region
    pfam13465
    Location:1265 → 1290
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:669 → 693
    zf-H2C2_5; C2H2-type zinc-finger domain

  8. XM_011244341.4 → XP_011242643.1  ras-responsive element-binding protein 1 isoform X4

    Conserved Domains (8) summary
    smart00355
    Location:1171 → 1191
    ZnF_C2H2; zinc finger
    sd00017
    Location:17 → 37
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:1520 → 1542
    zf-C2H2; Zinc finger, C2H2 type
    pfam04625
    Location:299 → 590
    DEC-1_N; DEC-1 protein, N-terminal region
    pfam13465
    Location:1506 → 1530
    zf-H2C2_2; Zinc-finger double domain
    pfam13894
    Location:124 → 146
    zf-C2H2_4; C2H2-type zinc finger
    pfam13909
    Location:587 → 611
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam13912
    Location:1493 → 1514
    zf-C2H2_6; C2H2-type zinc finger

  9. XM_006516756.4 → XP_006516819.1  ras-responsive element-binding protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006516819.1

    UniProtKB/Swiss-Prot
    Q3UH06
    Related
    ENSMUSP00000049265.8, ENSMUST00000037232.8
    Conserved Domains (8) summary
    smart00355
    Location:1253 → 1273
    ZnF_C2H2; zinc finger
    COG5048
    Location:64 → 244
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:68 → 88
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:1602 → 1624
    zf-C2H2; Zinc finger, C2H2 type
    pfam04625
    Location:381 → 672
    DEC-1_N; DEC-1 protein, N-terminal region
    pfam13465
    Location:1588 → 1612
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:669 → 693
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam13912
    Location:1575 → 1596
    zf-C2H2_6; C2H2-type zinc finger

  10. XM_006516751.4 → XP_006516814.1  ras-responsive element-binding protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006516814.1

    UniProtKB/Swiss-Prot
    Q3UH06
    Conserved Domains (8) summary
    smart00355
    Location:1253 → 1273
    ZnF_C2H2; zinc finger
    COG5048
    Location:64 → 244
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:68 → 88
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:1602 → 1624
    zf-C2H2; Zinc finger, C2H2 type
    pfam04625
    Location:381 → 672
    DEC-1_N; DEC-1 protein, N-terminal region
    pfam13465
    Location:1588 → 1612
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:669 → 693
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam13912
    Location:1575 → 1596
    zf-C2H2_6; C2H2-type zinc finger

  11. XM_006516752.3 → XP_006516815.1  ras-responsive element-binding protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006516815.1

    UniProtKB/Swiss-Prot
    Q3UH06
    Conserved Domains (8) summary
    smart00355
    Location:1253 → 1273
    ZnF_C2H2; zinc finger
    COG5048
    Location:64 → 244
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:68 → 88
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:1602 → 1624
    zf-C2H2; Zinc finger, C2H2 type
    pfam04625
    Location:381 → 672
    DEC-1_N; DEC-1 protein, N-terminal region
    pfam13465
    Location:1588 → 1612
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:669 → 693
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam13912
    Location:1575 → 1596
    zf-C2H2_6; C2H2-type zinc finger

  12. XM_006516753.5 → XP_006516816.1  ras-responsive element-binding protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006516816.1

    UniProtKB/Swiss-Prot
    Q3UH06
    Conserved Domains (8) summary
    smart00355
    Location:1253 → 1273
    ZnF_C2H2; zinc finger
    COG5048
    Location:64 → 244
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:68 → 88
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:1602 → 1624
    zf-C2H2; Zinc finger, C2H2 type
    pfam04625
    Location:381 → 672
    DEC-1_N; DEC-1 protein, N-terminal region
    pfam13465
    Location:1588 → 1612
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:669 → 693
    zf-H2C2_5; C2H2-type zinc-finger domain
    pfam13912
    Location:1575 → 1596
    zf-C2H2_6; C2H2-type zinc finger

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001013392.3: Suppressed sequence

    Description
    NM_001013392.3: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3UH06.2 GenPept UniProtKB/Swiss-Prot:Q3UH06

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