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ZFP69B ZFP69 zinc finger protein B [ Homo sapiens (human) ]

Gene ID: 65243, updated on 11-Jun-2021

Summary

Official Symbol
ZFP69Bprovided by HGNC
Official Full Name
ZFP69 zinc finger protein Bprovided by HGNC
Primary source
HGNC:HGNC:28053
See related
Ensembl:ENSG00000187801
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF643; ZSCAN54B; ZKSCAN23B
Expression
Ubiquitous expression in brain (RPKM 1.6), appendix (RPKM 1.1) and 25 other tissues See more
Orthologs
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Genomic context

See ZFP69B in Genome Data Viewer
Location:
1p34.2
Exon count:
6
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (40450064..40466765)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (40915736..40929387)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107984945 Neighboring gene small ArfGAP2 Neighboring gene ZFP69 zinc finger protein Neighboring gene EXO5 divergent transcript Neighboring gene exonuclease 5

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ34293

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in Golgi organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 69 homolog B
Names
novel zinc finger protein
zinc finger protein 643
zinc finger protein ZFP69B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001369565.1NP_001356494.1  zinc finger protein 69 homolog B

    Status: VALIDATED

    Source sequence(s)
    AL031985
    Related
    ENSP00000399664.2, ENST00000411995.6
    Conserved Domains (5) summary
    smart00349
    Location:74133
    KRAB; krueppel associated box
    COG5048
    Location:221429
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:309329
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:433458
    zf-H2C2_2; Zinc-finger double domain
    cl02605
    Location:240
    SCAN; SCAN oligomerization domain
  2. NM_023070.3NP_075558.2  zinc finger protein 69 homolog B

    See identical proteins and their annotated locations for NP_075558.2

    Status: VALIDATED

    Source sequence(s)
    AL031985, BC017498, CN256362
    Consensus CDS
    CCDS452.2
    UniProtKB/Swiss-Prot
    Q9UJL9
    UniProtKB/TrEMBL
    D3DPV3
    Related
    ENSP00000354547.4, ENST00000361584.5
    Conserved Domains (5) summary
    smart00349
    Location:74133
    KRAB; krueppel associated box
    COG5048
    Location:221429
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:309329
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:433458
    zf-H2C2_2; Zinc-finger double domain
    cl02605
    Location:240
    SCAN; SCAN oligomerization domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    40450064..40466765
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005271139.3XP_005271196.1  zinc finger protein 69 homolog B isoform X4

    See identical proteins and their annotated locations for XP_005271196.1

    UniProtKB/Swiss-Prot
    Q9UJL9
    Conserved Domains (4) summary
    COG5048
    Location:170235
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:207227
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:387412
    zf-H2C2_2; Zinc-finger double domain
    cl02581
    Location:131
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  2. XM_005271138.3XP_005271195.1  zinc finger protein 69 homolog B isoform X3

    Conserved Domains (4) summary
    COG5048
    Location:171236
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:208228
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:388413
    zf-H2C2_2; Zinc-finger double domain
    cl02581
    Location:132
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  3. XM_005271136.1XP_005271193.1  zinc finger protein 69 homolog B isoform X1

    Related
    ENST00000469416.1
    Conserved Domains (5) summary
    smart00349
    Location:74134
    KRAB; krueppel associated box
    COG5048
    Location:194430
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:310330
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:434459
    zf-H2C2_2; Zinc-finger double domain
    cl02605
    Location:240
    SCAN; SCAN oligomerization domain
  4. XM_017002147.1XP_016857636.1  zinc finger protein 69 homolog B isoform X1

    Conserved Domains (5) summary
    smart00349
    Location:74134
    KRAB; krueppel associated box
    COG5048
    Location:194430
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:310330
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:434459
    zf-H2C2_2; Zinc-finger double domain
    cl02605
    Location:240
    SCAN; SCAN oligomerization domain
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