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ZSCAN31 zinc finger and SCAN domain containing 31 [ Homo sapiens (human) ]

Gene ID: 64288, updated on 6-Sep-2021

Summary

Official Symbol
ZSCAN31provided by HGNC
Official Full Name
zinc finger and SCAN domain containing 31provided by HGNC
Primary source
HGNC:HGNC:14097
See related
Ensembl:ENSG00000235109 MIM:610794
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF323; ZNF310P; ZNF20-Lp
Summary
This gene encodes a protein containing multiple C2H2-type zinc finger motifs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Expression
Ubiquitous expression in ovary (RPKM 2.2), testis (RPKM 2.1) and 25 other tissues See more
Orthologs
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Genomic context

See ZSCAN31 in Genome Data Viewer
Location:
6p22.1; 6p22.3-p22.1
Exon count:
14
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (28324737..28359157, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (28292514..28324048, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene zinc finger and SCAN domain containing 26 Neighboring gene piggyBac transposable element derived 1 Neighboring gene zinc finger with KRAB and SCAN domains 3 Neighboring gene zinc finger and SCAN domain containing 12 Neighboring gene uncharacterized LOC105374998

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23407, FLJ41286

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger and SCAN domain-containing protein 31
Names
zinc finger protein 323

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135215.1NP_001128687.1  zinc finger and SCAN domain-containing protein 31 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) initiates transcription from an alternate promoter and differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4 and 7 encode the same isoform (1).
    Source sequence(s)
    AF513019, AK095261, AL021997
    UniProtKB/Swiss-Prot
    Q96LW9
    UniProtKB/TrEMBL
    A0A024RCL4, B3KTA4
    Related
    ENSP00000390076.1, ENST00000414429.5
    Conserved Domains (6) summary
    smart00431
    Location:35146
    SCAN; leucine rich region
    COG5048
    Location:156397
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:239261
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:35123
    SCAN; SCAN domain
    pfam13465
    Location:310332
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001135216.1NP_001128688.1  zinc finger and SCAN domain-containing protein 31 isoform 1

    See identical proteins and their annotated locations for NP_001128688.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4 and 7 encode the same isoform (1).
    Source sequence(s)
    AF513019, AL833617, BC008490
    Consensus CDS
    CCDS4649.1
    UniProtKB/Swiss-Prot
    Q96LW9
    UniProtKB/TrEMBL
    A0A024RCL4, Q96QL1
    Related
    ENSP00000413705.1, ENST00000439158.5
    Conserved Domains (6) summary
    smart00431
    Location:35146
    SCAN; leucine rich region
    COG5048
    Location:156397
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:239261
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:35123
    SCAN; SCAN domain
    pfam13465
    Location:310332
    zf-H2C2_2; Zinc-finger double domain
  3. NM_001243241.1NP_001230170.1  zinc finger and SCAN domain-containing protein 31 isoform 1

    See identical proteins and their annotated locations for NP_001230170.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4 and 7 encode the same isoform (1).
    Source sequence(s)
    BC065241, DA875036, DN995648
    Consensus CDS
    CCDS4649.1
    UniProtKB/Swiss-Prot
    Q96LW9
    UniProtKB/TrEMBL
    A0A024RCL4
    Conserved Domains (6) summary
    smart00431
    Location:35146
    SCAN; leucine rich region
    COG5048
    Location:156397
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:239261
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:35123
    SCAN; SCAN domain
    pfam13465
    Location:310332
    zf-H2C2_2; Zinc-finger double domain
  4. NM_001243242.1NP_001230171.1  zinc finger and SCAN domain-containing protein 31 isoform 2

    See identical proteins and their annotated locations for NP_001230171.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream, in-frame start codon, compared to variant 1. Variants 5, 6 and 8 encode the same isoform (2), which has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    BC065241, DA875036, DA879276
    Consensus CDS
    CCDS59001.1
    UniProtKB/Swiss-Prot
    Q96LW9
    Related
    ENSP00000480254.1, ENST00000611469.4
    Conserved Domains (2) summary
    COG5048
    Location:79238
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:82102
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. NM_001243243.1NP_001230172.1  zinc finger and SCAN domain-containing protein 31 isoform 2

    See identical proteins and their annotated locations for NP_001230172.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream, in-frame start codon, compared to variant 1. Variants 5, 6 and 8 encode the same isoform (2), which has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AL833617, BC065241
    Consensus CDS
    CCDS59001.1
    UniProtKB/Swiss-Prot
    Q96LW9
    Related
    ENSP00000402937.1, ENST00000446474.5
    Conserved Domains (2) summary
    COG5048
    Location:79238
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:82102
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. NM_001243244.1NP_001230173.1  zinc finger and SCAN domain-containing protein 31 isoform 2

    See identical proteins and their annotated locations for NP_001230173.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks a portion of the 5' coding region and uses a downstream, in-frame start codon, compared to variant 1. Variants 5, 6 and 8 encode the same isoform (2), which has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    BC065241, DA875036
    Consensus CDS
    CCDS59001.1
    UniProtKB/Swiss-Prot
    Q96LW9
    Related
    ENSP00000391235.1, ENST00000435857.5
    Conserved Domains (2) summary
    COG5048
    Location:79238
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:82102
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. NM_030899.5NP_112161.3  zinc finger and SCAN domain-containing protein 31 isoform 1

    See identical proteins and their annotated locations for NP_112161.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform 1. Variants 1, 2, 3, 4 and 7 encode the same isoform (1).
    Source sequence(s)
    AL021997
    Consensus CDS
    CCDS4649.1
    UniProtKB/Swiss-Prot
    Q96LW9
    UniProtKB/TrEMBL
    A0A024RCL4, Q96QL1
    Related
    ENSP00000345339.6, ENST00000344279.11
    Conserved Domains (6) summary
    smart00431
    Location:35146
    SCAN; leucine rich region
    COG5048
    Location:156397
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:239261
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:35123
    SCAN; SCAN domain
    pfam13465
    Location:310332
    zf-H2C2_2; Zinc-finger double domain
  8. NM_145909.3NP_665916.1  zinc finger and SCAN domain-containing protein 31 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4 and 7 encode the same isoform (1).
    Source sequence(s)
    AF513019, AL021997
    UniProtKB/Swiss-Prot
    Q96LW9
    UniProtKB/TrEMBL
    A0A024RCL4
    Related
    ENSP00000380050.2, ENST00000396838.6
    Conserved Domains (6) summary
    smart00431
    Location:35146
    SCAN; leucine rich region
    COG5048
    Location:156397
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:239261
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:35123
    SCAN; SCAN domain
    pfam13465
    Location:310332
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    28324737..28359157 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011514808.3XP_011513110.1  zinc finger and SCAN domain-containing protein 31 isoform X1

    See identical proteins and their annotated locations for XP_011513110.1

    UniProtKB/Swiss-Prot
    Q96LW9
    UniProtKB/TrEMBL
    A0A024RCL4
    Conserved Domains (6) summary
    smart00431
    Location:35146
    SCAN; leucine rich region
    COG5048
    Location:156397
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:239261
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:35123
    SCAN; SCAN domain
    pfam13465
    Location:310332
    zf-H2C2_2; Zinc-finger double domain
  2. XM_005249296.5XP_005249353.1  zinc finger and SCAN domain-containing protein 31 isoform X1

    See identical proteins and their annotated locations for XP_005249353.1

    UniProtKB/Swiss-Prot
    Q96LW9
    UniProtKB/TrEMBL
    A0A024RCL4
    Conserved Domains (6) summary
    smart00431
    Location:35146
    SCAN; leucine rich region
    COG5048
    Location:156397
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:239261
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:35123
    SCAN; SCAN domain
    pfam13465
    Location:310332
    zf-H2C2_2; Zinc-finger double domain
  3. XM_017011196.2XP_016866685.1  zinc finger and SCAN domain-containing protein 31 isoform X1

    UniProtKB/Swiss-Prot
    Q96LW9
    UniProtKB/TrEMBL
    A0A024RCL4
    Conserved Domains (6) summary
    smart00431
    Location:35146
    SCAN; leucine rich region
    COG5048
    Location:156397
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:239261
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:35123
    SCAN; SCAN domain
    pfam13465
    Location:310332
    zf-H2C2_2; Zinc-finger double domain
  4. XM_011514807.3XP_011513109.1  zinc finger and SCAN domain-containing protein 31 isoform X1

    See identical proteins and their annotated locations for XP_011513109.1

    UniProtKB/Swiss-Prot
    Q96LW9
    UniProtKB/TrEMBL
    A0A024RCL4
    Conserved Domains (6) summary
    smart00431
    Location:35146
    SCAN; leucine rich region
    COG5048
    Location:156397
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:239261
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:35123
    SCAN; SCAN domain
    pfam13465
    Location:310332
    zf-H2C2_2; Zinc-finger double domain
  5. XM_024446522.1XP_024302290.1  zinc finger and SCAN domain-containing protein 31 isoform X3

    Conserved Domains (2) summary
    COG5048
    Location:79238
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:82102
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. XM_024446523.1XP_024302291.1  zinc finger and SCAN domain-containing protein 31 isoform X3

    Conserved Domains (2) summary
    COG5048
    Location:79238
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:82102
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. XM_024446521.1XP_024302289.1  zinc finger and SCAN domain-containing protein 31 isoform X2

    Conserved Domains (2) summary
    COG5048
    Location:122281
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:125145
    ZF_C2H2; C2H2 Zn finger [structural motif]
  8. XM_005249295.1XP_005249352.1  zinc finger and SCAN domain-containing protein 31 isoform X1

    See identical proteins and their annotated locations for XP_005249352.1

    UniProtKB/Swiss-Prot
    Q96LW9
    UniProtKB/TrEMBL
    A0A024RCL4
    Conserved Domains (6) summary
    smart00431
    Location:35146
    SCAN; leucine rich region
    COG5048
    Location:156397
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:239261
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:35123
    SCAN; SCAN domain
    pfam13465
    Location:310332
    zf-H2C2_2; Zinc-finger double domain
  9. XM_011514812.2XP_011513114.1  zinc finger and SCAN domain-containing protein 31 isoform X1

    See identical proteins and their annotated locations for XP_011513114.1

    UniProtKB/Swiss-Prot
    Q96LW9
    UniProtKB/TrEMBL
    A0A024RCL4
    Conserved Domains (6) summary
    smart00431
    Location:35146
    SCAN; leucine rich region
    COG5048
    Location:156397
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:239261
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:35123
    SCAN; SCAN domain
    pfam13465
    Location:310332
    zf-H2C2_2; Zinc-finger double domain
  10. XM_011514813.2XP_011513115.1  zinc finger and SCAN domain-containing protein 31 isoform X1

    See identical proteins and their annotated locations for XP_011513115.1

    UniProtKB/Swiss-Prot
    Q96LW9
    UniProtKB/TrEMBL
    A0A024RCL4
    Conserved Domains (6) summary
    smart00431
    Location:35146
    SCAN; leucine rich region
    COG5048
    Location:156397
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:239261
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:35123
    SCAN; SCAN domain
    pfam13465
    Location:310332
    zf-H2C2_2; Zinc-finger double domain
  11. XM_011514811.2XP_011513113.1  zinc finger and SCAN domain-containing protein 31 isoform X1

    See identical proteins and their annotated locations for XP_011513113.1

    UniProtKB/Swiss-Prot
    Q96LW9
    UniProtKB/TrEMBL
    A0A024RCL4
    Conserved Domains (6) summary
    smart00431
    Location:35146
    SCAN; leucine rich region
    COG5048
    Location:156397
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:239261
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:35123
    SCAN; SCAN domain
    pfam13465
    Location:310332
    zf-H2C2_2; Zinc-finger double domain
  12. XM_011514809.1XP_011513111.1  zinc finger and SCAN domain-containing protein 31 isoform X1

    See identical proteins and their annotated locations for XP_011513111.1

    UniProtKB/Swiss-Prot
    Q96LW9
    UniProtKB/TrEMBL
    A0A024RCL4
    Conserved Domains (6) summary
    smart00431
    Location:35146
    SCAN; leucine rich region
    COG5048
    Location:156397
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:239261
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:35123
    SCAN; SCAN domain
    pfam13465
    Location:310332
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. XR_002956295.1 RNA Sequence

  2. XR_002956296.1 RNA Sequence

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