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Sdf2l1 stromal cell-derived factor 2-like 1 [ Mus musculus (house mouse) ]

Gene ID: 64136, updated on 26-Sep-2022

Summary

Official Symbol
Sdf2l1provided by MGI
Official Full Name
stromal cell-derived factor 2-like 1provided by MGI
Primary source
MGI:MGI:2149842
See related
Ensembl:ENSMUSG00000022769 AllianceGenome:MGI:2149842
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable ATPase binding activity; chaperone binding activity; and misfolded protein binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding. Predicted to act upstream of or within ER-associated misfolded protein catabolic process and regulation of apoptotic process. Part of endoplasmic reticulum chaperone complex. Is expressed in ventricular layer. Orthologous to human SDF2L1 (stromal cell derived factor 2 like 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 56.1), colon adult (RPKM 48.1) and 28 other tissues See more
Orthologs
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Genomic context

See Sdf2l1 in Genome Data Viewer
Location:
16; 16 A3
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (16948002..16950247, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (17130138..17132383, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2610318N02 gene Neighboring gene microRNA 130b Neighboring gene microRNA 301b Neighboring gene Rps20 pseudogene Neighboring gene coiled-coil domain containing 116 Neighboring gene YdjC homolog (bacterial)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATPase binding ISO
Inferred from Sequence Orthology
more info
PubMed 
enables chaperone binding ISO
Inferred from Sequence Orthology
more info
PubMed 
enables misfolded protein binding ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
part_of chaperone complex ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum ISA
Inferred from Sequence Alignment
more info
PubMed 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
PubMed 
part_of endoplasmic reticulum chaperone complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
stromal cell-derived factor 2-like protein 1
Names
SDF2-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022324.3NP_071719.1  stromal cell-derived factor 2-like protein 1 precursor

    See identical proteins and their annotated locations for NP_071719.1

    Status: VALIDATED

    Source sequence(s)
    BC053425, BY253823
    Consensus CDS
    CCDS37270.1
    UniProtKB/Swiss-Prot
    Q9ESP1, Q9ESP2
    UniProtKB/TrEMBL
    A0A8C6HGE3
    Related
    ENSMUSP00000023453.8, ENSMUST00000023453.10
    Conserved Domains (2) summary
    smart00472
    Location:95150
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    cl19745
    Location:159201
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    16948002..16950247 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)