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CNGA2 cyclic nucleotide gated channel subunit alpha 2 [ Canis lupus familiaris (dog) ]

Gene ID: 612414, updated on 17-Aug-2024

Summary

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Official Symbol
CNGA2provided by VGNC
Official Full Name
cyclic nucleotide gated channel subunit alpha 2provided by VGNC
Primary source
VGNC:VGNC:39396
See related
Ensembl:ENSCAFG00845025318
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X
Exon count:
6
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (121916523..121923183)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (105078713..105085373)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (121002320..121008981)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (118636774..118643434)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (121119721..121126381)

Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene proline rich and Gla domain 3 Neighboring gene fetal and adult testis expressed 1 Neighboring gene thioredoxin-like Neighboring gene melanoma-associated antigen 10-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cGMP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables intracellularly cAMP-activated cation channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables intracellularly cGMP-activated cation channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein-containing complex binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in monoatomic cation transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of intracellular cyclic nucleotide activated cation channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cyclic nucleotide-gated olfactory channel
Names
cyclic nucleotide gated channel alpha 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051843.1 Reference ROS_Cfam_1.0

    Range
    121916523..121923183
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038449229.1 → XP_038305157.1  cyclic nucleotide-gated olfactory channel

    UniProtKB/TrEMBL
    A0A8C0SQM0, A0A8I3PQE3
    Related
    ENSCAFP00845035035.1, ENSCAFT00845044714.1
    Conserved Domains (4) summary
    cd00038
    Location:454 → 570
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
    pfam00520
    Location:140 → 382
    Ion_trans; Ion transport protein
    pfam16526
    Location:570 → 637
    CLZ; C-terminal leucine zipper domain of cyclic nucleotide-gated channels
    cl18962
    Location:415 → 468
    Radical_SAM; Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster. ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049299.1 Alternate UMICH_Zoey_3.1

    Range
    118636774..118643434
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038524884.1 → XP_038380812.1  cyclic nucleotide-gated olfactory channel

    Conserved Domains (4) summary
    cd00038
    Location:454 → 570
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
    pfam00520
    Location:140 → 382
    Ion_trans; Ion transport protein
    pfam16526
    Location:570 → 637
    CLZ; C-terminal leucine zipper domain of cyclic nucleotide-gated channels
    cl18962
    Location:415 → 468
    Radical_SAM; Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster. ...

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

    Range
    121119721..121126381
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038651176.1 → XP_038507104.1  cyclic nucleotide-gated olfactory channel

    Conserved Domains (4) summary
    cd00038
    Location:454 → 570
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
    pfam00520
    Location:140 → 382
    Ion_trans; Ion transport protein
    pfam16526
    Location:570 → 637
    CLZ; C-terminal leucine zipper domain of cyclic nucleotide-gated channels
    cl18962
    Location:415 → 468
    Radical_SAM; Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster. ...

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

    Range
    121002320..121008981
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038588852.1 → XP_038444780.1  cyclic nucleotide-gated olfactory channel

    UniProtKB/TrEMBL
    A0A8C0SQM0, A0A8I3PQE3
    Conserved Domains (4) summary
    cd00038
    Location:454 → 570
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
    pfam00520
    Location:140 → 382
    Ion_trans; Ion transport protein
    pfam16526
    Location:570 → 637
    CLZ; C-terminal leucine zipper domain of cyclic nucleotide-gated channels
    cl18962
    Location:415 → 468
    Radical_SAM; Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster. ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    105078713..105085373
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005641957.4 → XP_005642014.1  cyclic nucleotide-gated olfactory channel

    UniProtKB/TrEMBL
    A0A8C0SQM0, A0A8I3PQE3
    Conserved Domains (4) summary
    cd00038
    Location:454 → 570
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
    pfam00520
    Location:140 → 382
    Ion_trans; Ion transport protein
    pfam16526
    Location:570 → 637
    CLZ; C-terminal leucine zipper domain of cyclic nucleotide-gated channels
    cl18962
    Location:415 → 468
    Radical_SAM; Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster. ...
Nucleotide Protein
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