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ZNF77 zinc finger protein 77 [ Homo sapiens (human) ]

Gene ID: 58492, updated on 23-Nov-2021

Summary

Official Symbol
ZNF77provided by HGNC
Official Full Name
zinc finger protein 77provided by HGNC
Primary source
HGNC:HGNC:13150
See related
Ensembl:ENSG00000175691 MIM:194551
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
pT1
Expression
Ubiquitous expression in thyroid (RPKM 1.9), testis (RPKM 1.7) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF77 in Genome Data Viewer
Location:
19p13.3
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (2933218..2944971, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (2933216..2944969, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 57 pseudogene Neighboring gene uncharacterized LOC101928631 Neighboring gene zinc finger protein 57 Neighboring gene TLE family member 6, subcortical maternal complex member Neighboring gene TLE family member 2, transcriptional corepressor

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 77
Names
ZNFpT1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021217.3NP_067040.1  zinc finger protein 77

    See identical proteins and their annotated locations for NP_067040.1

    Status: VALIDATED

    Source sequence(s)
    AC006277, AC011559
    Consensus CDS
    CCDS12099.1
    UniProtKB/Swiss-Prot
    Q15935
    Related
    ENSP00000319053.3, ENST00000314531.5
    Conserved Domains (3) summary
    COG5048
    Location:237544
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:410430
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:444
    KRAB; KRAB box

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    2933218..2944971 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017027081.1XP_016882570.1  zinc finger protein 77 isoform X1

  2. XM_017027082.1XP_016882571.1  zinc finger protein 77 isoform X1

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