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ZBTB26 zinc finger and BTB domain containing 26 [ Homo sapiens (human) ]

Gene ID: 57684, updated on 23-Nov-2021

Summary

Official Symbol
ZBTB26provided by HGNC
Official Full Name
zinc finger and BTB domain containing 26provided by HGNC
Primary source
HGNC:HGNC:23383
See related
Ensembl:ENSG00000171448
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF481; bioref
Expression
Ubiquitous expression in testis (RPKM 7.0), ovary (RPKM 4.9) and 25 other tissues See more
Orthologs
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Genomic context

See ZBTB26 in Genome Data Viewer
Location:
9q33.2
Exon count:
3
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (122915566..122931512, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (125677845..125693791, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene ring finger and CCCH-type domains 2 Neighboring gene small nucleolar RNA, C/D box 90 Neighboring gene zinc finger and BTB domain containing 6 Neighboring gene uncharacterized LOC105379839 Neighboring gene RAB GTPase activating protein 1 Neighboring gene RNY1 pseudogene 15

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: ZBTB6

Homology

Clone Names

  • KIAA1572

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables sequence-specific double-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger and BTB domain-containing protein 26
Names
zinc finger protein 481
zinc finger protein 483
zinc finger protein Bioref

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001304363.2NP_001291292.1  zinc finger and BTB domain-containing protein 26

    See identical proteins and their annotated locations for NP_001291292.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an alternate splice site in the 5' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC007066, AK058083, BC018748, BM682342, DA212731
    Consensus CDS
    CCDS6847.1
    UniProtKB/Swiss-Prot
    Q9HCK0
    Conserved Domains (5) summary
    COG5236
    Location:269381
    COG5236; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
    sd00017
    Location:300320
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18214
    Location:8129
    BTB_POZ_ZBTB26_Bioref; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 26 (ZBTB26)
    pfam00096
    Location:298320
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:315337
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001304364.2NP_001291293.1  zinc finger and BTB domain-containing protein 26

    See identical proteins and their annotated locations for NP_001291293.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has an alternate 5' UTR exon, compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC007066, AK057445, AK058083, BM682342
    Consensus CDS
    CCDS6847.1
    UniProtKB/Swiss-Prot
    Q9HCK0
    Related
    ENSP00000362758.1, ENST00000373654.1
    Conserved Domains (5) summary
    COG5236
    Location:269381
    COG5236; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
    sd00017
    Location:300320
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18214
    Location:8129
    BTB_POZ_ZBTB26_Bioref; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 26 (ZBTB26)
    pfam00096
    Location:298320
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:315337
    zf-H2C2_2; Zinc-finger double domain
  3. NM_020924.4NP_065975.1  zinc finger and BTB domain-containing protein 26

    See identical proteins and their annotated locations for NP_065975.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) and variants 2 and 3 encode the same protein.
    Source sequence(s)
    AC007066, AK058083, BC018748, BM682342, HY066289
    Consensus CDS
    CCDS6847.1
    UniProtKB/Swiss-Prot
    Q9HCK0
    Related
    ENSP00000362760.3, ENST00000373656.4
    Conserved Domains (5) summary
    COG5236
    Location:269381
    COG5236; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
    sd00017
    Location:300320
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18214
    Location:8129
    BTB_POZ_ZBTB26_Bioref; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 26 (ZBTB26)
    pfam00096
    Location:298320
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:315337
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    122915566..122931512 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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