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FAM135A family with sequence similarity 135 member A [ Homo sapiens (human) ]

Gene ID: 57579, updated on 12-Oct-2019

Summary

Official Symbol
FAM135Aprovided by HGNC
Official Full Name
family with sequence similarity 135 member Aprovided by HGNC
Primary source
HGNC:HGNC:21084
See related
Ensembl:ENSG00000082269
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KIAA1411
Expression
Broad expression in esophagus (RPKM 17.6), prostate (RPKM 12.9) and 22 other tissues See more
Orthologs

Genomic context

See FAM135A in Genome Data Viewer
Location:
6q13
Exon count:
25
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (70413404..70561174)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (71123107..71270877)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105377848 Neighboring gene uncharacterized LOC105377847 Neighboring gene FAM135A antisense RNA 1 Neighboring gene uncharacterized LOC101928353 Neighboring gene RNA, U7 small nuclear 48 pseudogene Neighboring gene succinate dehydrogenase complex assembly factor 4 Neighboring gene spermine synthase pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ13577, KIAA1411, DKFZp781H2319

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cellular lipid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_054903.1 RefSeqGene

    Range
    5001..152771
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001105531.2NP_001099001.1  protein FAM135A isoform a

    Status: VALIDATED

    Source sequence(s)
    AB037832, AJ420590, BC131782, DB462733
    Consensus CDS
    CCDS47448.1
    UniProtKB/Swiss-Prot
    Q9P2D6
    Related
    ENSP00000354913.3, ENST00000361499.7
    Conserved Domains (2) summary
    pfam05057
    Location:10481243
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein of unknown function (DUF3657)
  2. NM_001162529.2NP_001156001.1  protein FAM135A isoform c

    See identical proteins and their annotated locations for NP_001156001.1

    Status: VALIDATED

    Source sequence(s)
    AB037832, AJ420590, AL365226, BC131782
    Consensus CDS
    CCDS55028.1
    UniProtKB/Swiss-Prot
    Q9P2D6
    Related
    ENSP00000410768.2, ENST00000418814.6
    Conserved Domains (2) summary
    pfam05057
    Location:12441439
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein FAM135
  3. NM_001330995.2NP_001317924.1  protein FAM135A isoform d

    Status: VALIDATED

    Source sequence(s)
    AJ420590, AL078591, AL365226
    Consensus CDS
    CCDS83104.1
    UniProtKB/TrEMBL
    D6RCC7
    Related
    ENSP00000423785.1, ENST00000505769.5
  4. NM_001330996.2NP_001317925.1  protein FAM135A isoform e

    Status: VALIDATED

    Source sequence(s)
    AJ420590, AL078591, AL365226
    Conserved Domains (2) summary
    pfam05057
    Location:12701465
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein FAM135
  5. NM_001330997.2NP_001317926.1  protein FAM135A isoform a

    Status: VALIDATED

    Source sequence(s)
    AJ420590, AL078591, AL365226
    Consensus CDS
    CCDS47448.1
    UniProtKB/Swiss-Prot
    Q9P2D6
    Conserved Domains (2) summary
    pfam05057
    Location:10481243
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein of unknown function (DUF3657)
  6. NM_001330998.2NP_001317927.1  protein FAM135A isoform f

    Status: VALIDATED

    Source sequence(s)
    AJ420590, AL078591, AL365226
    Conserved Domains (2) summary
    pfam05057
    Location:10741269
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein of unknown function (DUF3657)
  7. NM_001330999.2NP_001317928.1  protein FAM135A isoform e

    Status: VALIDATED

    Source sequence(s)
    AJ420590, AL078591, AL365226
    Conserved Domains (2) summary
    pfam05057
    Location:12701465
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein FAM135
  8. NM_001331000.2NP_001317929.1  protein FAM135A isoform g

    Status: VALIDATED

    Source sequence(s)
    AJ420590, AL078591, AL365226
  9. NM_001331001.2NP_001317930.1  protein FAM135A isoform a

    Status: VALIDATED

    Source sequence(s)
    AJ420590, AL078591, AL365226
    Consensus CDS
    CCDS47448.1
    UniProtKB/Swiss-Prot
    Q9P2D6
    Conserved Domains (2) summary
    pfam05057
    Location:10481243
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein of unknown function (DUF3657)
  10. NM_001331002.2NP_001317931.1  protein FAM135A isoform a

    Status: VALIDATED

    Source sequence(s)
    AJ420590, AL078591, AL365226
    Consensus CDS
    CCDS47448.1
    UniProtKB/Swiss-Prot
    Q9P2D6
    Conserved Domains (2) summary
    pfam05057
    Location:10481243
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein of unknown function (DUF3657)
  11. NM_001331003.2NP_001317932.1  protein FAM135A isoform f

    Status: VALIDATED

    Source sequence(s)
    AJ420590, AL078591, AL365226
    Conserved Domains (2) summary
    pfam05057
    Location:10741269
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein of unknown function (DUF3657)
  12. NM_001331004.2NP_001317933.1  protein FAM135A isoform h

    Status: VALIDATED

    Source sequence(s)
    AJ420590, AL078591, AL365226
  13. NM_001331005.2NP_001317934.1  protein FAM135A isoform i

    Status: VALIDATED

    Source sequence(s)
    AJ420590, AL078591, AL365226
  14. NM_001331006.2NP_001317935.1  protein FAM135A isoform j

    Status: VALIDATED

    Source sequence(s)
    AJ420590, AL078591, AL365226
    Conserved Domains (2) summary
    pfam05057
    Location:8501045
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein of unknown function (DUF3657)
  15. NM_001351599.1NP_001338528.1  protein FAM135A isoform e

    Status: VALIDATED

    Source sequence(s)
    AJ420590, AL078591, AL365226
    Conserved Domains (2) summary
    pfam05057
    Location:12701465
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein FAM135
  16. NM_001351600.1NP_001338529.1  protein FAM135A isoform c

    Status: VALIDATED

    Source sequence(s)
    AJ420590, AL078591, AL365226
    Consensus CDS
    CCDS55028.1
    Related
    ENSP00000359510.4, ENST00000370479.7
    Conserved Domains (2) summary
    pfam05057
    Location:12441439
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein FAM135
  17. NM_001351602.1NP_001338531.1  protein FAM135A isoform c

    Status: VALIDATED

    Source sequence(s)
    AJ420590, AL078591, AL365226
    Consensus CDS
    CCDS55028.1
    Conserved Domains (2) summary
    pfam05057
    Location:12441439
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein FAM135
  18. NM_001351607.1NP_001338536.1  protein FAM135A isoform c

    Status: VALIDATED

    Source sequence(s)
    AJ420590, AL078591, AL365226
    Consensus CDS
    CCDS55028.1
    Conserved Domains (2) summary
    pfam05057
    Location:12441439
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein FAM135
  19. NM_001351608.1NP_001338537.1  protein FAM135A isoform k

    Status: VALIDATED

    Source sequence(s)
    AJ420590, AL078591, AL365226
    Conserved Domains (2) summary
    pfam05057
    Location:9621157
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:2585
    DUF3657; Protein FAM135
  20. NM_001351609.1NP_001338538.1  protein FAM135A isoform l

    Status: VALIDATED

    Source sequence(s)
    AJ420590, AL078591, AL365226
    Conserved Domains (2) summary
    pfam05057
    Location:764959
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:2585
    DUF3657; Protein FAM135
  21. NM_020819.4NP_065870.3  protein FAM135A isoform b

    Status: VALIDATED

    Source sequence(s)
    AB037832, AJ420590, BC131782, CR749254, DB462733
    Consensus CDS
    CCDS34481.1
    UniProtKB/Swiss-Prot
    Q9P2D6
    Related
    ENSP00000409201.2, ENST00000457062.6
    Conserved Domains (2) summary
    pfam05057
    Location:10311226
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:68128
    DUF3657; Protein of unknown function (DUF3657)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    70413404..70561174
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011535995.3XP_011534297.1  protein FAM135A isoform X1

    See identical proteins and their annotated locations for XP_011534297.1

    Conserved Domains (2) summary
    pfam05057
    Location:12701465
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein FAM135
  2. XM_011535994.2XP_011534296.1  protein FAM135A isoform X1

    See identical proteins and their annotated locations for XP_011534296.1

    Conserved Domains (2) summary
    pfam05057
    Location:12701465
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein FAM135
  3. XM_011535996.2XP_011534298.1  protein FAM135A isoform X1

    See identical proteins and their annotated locations for XP_011534298.1

    Conserved Domains (2) summary
    pfam05057
    Location:12701465
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein FAM135
  4. XM_011535997.2XP_011534299.1  protein FAM135A isoform X3

    Conserved Domains (2) summary
    pfam05057
    Location:12371432
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:78138
    DUF3657; Protein of unknown function (DUF3657)
  5. XM_017011127.1XP_016866616.1  protein FAM135A isoform X2

    UniProtKB/Swiss-Prot
    Q9P2D6
    Related
    ENSP00000423307.1, ENST00000505868.1
    Conserved Domains (2) summary
    pfam05057
    Location:12441439
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein FAM135
  6. XM_005248749.1XP_005248806.1  protein FAM135A isoform X4

    Conserved Domains (2) summary
    pfam05057
    Location:10461241
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein of unknown function (DUF3657)
  7. XM_011535993.3XP_011534295.1  protein FAM135A isoform X1

    See identical proteins and their annotated locations for XP_011534295.1

    Conserved Domains (2) summary
    pfam05057
    Location:12701465
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111171
    DUF3657; Protein FAM135
  8. XM_017011136.1XP_016866625.1  protein FAM135A isoform X5

    Conserved Domains (1) summary
    pfam05057
    Location:8191014
    DUF676; Putative serine esterase (DUF676)
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