slc25a6 solute carrier family 25 member 6 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: slc25a6provided by ZNC
Official Full Name: solute carrier family 25 member 6provided by ZNC
Primary source: ZFIN:ZDB-GENE-070912-446
See related: Ensembl:ENSDARG00000005853 AllianceGenome:ZFIN:ZDB-GENE-070912-446
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fj78b08; si:dkey-21o13.4
Summary: Predicted to enable ATP:ADP antiporter activity. Predicted to act upstream of or within mitochondrial ADP transmembrane transport and mitochondrial ATP transmembrane transport. Predicted to be located in mitochondrial inner membrane. Predicted to be integral component of membrane. Orthologous to human SLC25A6 (solute carrier family 25 member 6). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 9

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (34866555..34871996, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (35057370..35062811, complement)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Dosage of the pseudoautosomal gene SLC25A6 is implicated in QTc interval duration.
Title: Dosage of the pseudoautosomal gene SLC25A6 is implicated in QTc interval duration.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP:ADP antiporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within mitochondrial ADP transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mitochondrial ATP transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ADP/ATP translocase 3

Names: solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001128732.1 → NP_001122204.1 ADP/ATP translocase 3

See identical proteins and their annotated locations for NP_001122204.1

Status: PROVISIONAL

Source sequence(s)

BC162783

UniProtKB/TrEMBL

B0S730, B3DHI8

Related

ENSDARP00000022077.7, ENSDART00000026378.8

Conserved Domains (2) summary

PTZ00169
Location:7 → 298

PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

pfam00153
Location:7 → 101

Mito_carr; Mitochondrial carrier protein