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cdk16 cyclin dependent kinase 16 [ Danio rerio (zebrafish) ]

Gene ID: 559750, updated on 12-Sep-2024

Summary

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Official Symbol
cdk16provided by ZNC
Official Full Name
cyclin dependent kinase 16provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-2939
See related
Ensembl:ENSDARG00000032072 AllianceGenome:ZFIN:ZDB-GENE-030131-2939
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc22a06; wu:fc22a06; si:dkey-31k5.1
Summary
Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including exocytosis; protein phosphorylation; and regulation of transcription involved in G1/S transition of mitotic cell cycle. Predicted to act upstream of or within phosphorylation. Predicted to be active in cytoplasm and nucleus. Predicted to colocalize with synaptic vesicle. Orthologous to human CDK16 (cyclin dependent kinase 16). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (8362441..8446417, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (8323397..8408085, complement)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene SRSF protein kinase 3 Neighboring gene TSR2 ribosome maturation factor Neighboring gene uncharacterized LOC137496291 Neighboring gene catechol-O-methyltransferase a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes. Briolat V, et al. J Immunol, 2014 May 1. PMID 24683187
  2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables cyclin-dependent protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in neuron projection development IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
colocalizes_with synaptic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cell division protein kinase 16; cyclin-dependent kinase 16
XP_001335575.1
XP_021334043.1
XP_021334044.1
XP_068079200.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    8362441..8446417 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068223099.1 → XP_068079200.1  cyclin-dependent kinase 16 isoform X4

  2. XM_021478369.2 → XP_021334044.1  cyclin-dependent kinase 16 isoform X3

    UniProtKB/TrEMBL
    A0A8M9Q9Y3
    Related
    ENSDARP00000157426.1, ENSDART00000191686.1
    Conserved Domains (1) summary
    cd07873
    Location:135 → 431
    STKc_PCTAIRE1; Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-1 kinase

  3. XM_001335539.8 → XP_001335575.1  cyclin-dependent kinase 16 isoform X2

    UniProtKB/TrEMBL
    A0A8M1PYZ8, B0UYG3
    Related
    ENSDARP00000119498.1, ENSDART00000137382.3
    Conserved Domains (2) summary
    PLN00009
    Location:190 → 478
    PLN00009; cyclin-dependent kinase A; Provisional
    cd07873
    Location:190 → 486
    STKc_PCTAIRE1; Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-1 kinase

  4. XM_021478368.2 → XP_021334043.1  cyclin-dependent kinase 16 isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q3R1
    Conserved Domains (1) summary
    cd07873
    Location:190 → 486
    STKc_PCTAIRE1; Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-1 kinase

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001030132.1: Suppressed sequence

    Description
    NM_001030132.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein Strain
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