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ZNF395 zinc finger protein 395 [ Homo sapiens (human) ]

Gene ID: 55893, updated on 1-Jun-2020

Summary

Official Symbol
ZNF395provided by HGNC
Official Full Name
zinc finger protein 395provided by HGNC
Primary source
HGNC:HGNC:18737
See related
Ensembl:ENSG00000186918 MIM:609494
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PBF; PRF1; HDBP2; PRF-1; HDBP-2; HDRF-2; Si-1-8-14
Expression
Ubiquitous expression in ovary (RPKM 29.1), placenta (RPKM 20.8) and 25 other tissues See more
Orthologs

Genomic context

See ZNF395 in Genome Data Viewer
Location:
8p21.1
Exon count:
10
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (28345590..28386460, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (28203102..28243983, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene ribosomal protein L5 pseudogene 22 Neighboring gene prepronociceptin Neighboring gene RNA, U6 small nuclear 178, pseudogene Neighboring gene F-box protein 16

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: FBXO16

Homology

Clone Names

  • DKFZp434K1210

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase II proximal promoter sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase II proximal promoter sequence-specific DNA binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription, DNA-templated IC
Inferred by Curator
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 395
Names
HD gene regulatory region-binding protein 2
HD-regulating factor 2
Huntington's disease gene regulatory region-binding protein 2
huntington disease gene regulatory region-binding protein 2
papillomavirus regulatory factor 1
papillomavirus regulatory factor PRF-1
papillomavirus-binding factor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018660.3NP_061130.1  zinc finger protein 395

    See identical proteins and their annotated locations for NP_061130.1

    Status: VALIDATED

    Source sequence(s)
    AI049727, AK023418, AK026076, AL137588, BC008870, BG249131, BG759384, BI917232, CB960515
    Consensus CDS
    CCDS6067.1
    UniProtKB/Swiss-Prot
    Q9H8N7
    UniProtKB/TrEMBL
    Q7L9C8
    Related
    ENSP00000340494.5, ENST00000344423.10
    Conserved Domains (1) summary
    pfam15997
    Location:21109
    DUF4772; Domain of unknown function (DUF4772)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    28345590..28386460 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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