Format

Send to:

Choose Destination

ZNF415 zinc finger protein 415 [ Homo sapiens (human) ]

Gene ID: 55786, updated on 23-Nov-2021

Summary

Official Symbol
ZNF415provided by HGNC
Official Full Name
zinc finger protein 415provided by HGNC
Primary source
HGNC:HGNC:20636
See related
Ensembl:ENSG00000170954 MIM:619506
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Pact; ZfLp
Expression
Broad expression in testis (RPKM 8.7), adrenal (RPKM 5.5) and 22 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See ZNF415 in Genome Data Viewer
Location:
19q13.42
Exon count:
9
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (53107879..53132952, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (53611132..53636163, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene endogenous retrovirus group V member 2, envelope Neighboring gene zinc finger protein 160 Neighboring gene zinc finger protein 347 Neighboring gene Sharpr-MPRA regulatory region 171 Neighboring gene zinc finger protein 665

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ11191

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in fibrillar center IDA
Inferred from Direct Assay
more info
 
located_in microtubule cytoskeleton IDA
Inferred from Direct Assay
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001136038.4NP_001129510.2  zinc finger protein 415 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform 1.Variants 1, 18, 19 and 20 encode the same protein (isoform 1).
    Source sequence(s)
    AC010328, DA367299, DA518713, DA692431, R40095
    Consensus CDS
    CCDS54313.1
    UniProtKB/Swiss-Prot
    Q09FC8
    Related
    ENSP00000439435.1, ENST00000500065.8
    Conserved Domains (3) summary
    COG5048
    Location:244539
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:358378
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:646
    KRAB; KRAB box
  2. NM_001164309.3NP_001157781.1  zinc finger protein 415 isoform 2

    See identical proteins and their annotated locations for NP_001157781.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate exon containing a distinct start codon, compared to variant 1. The resulting isoform (2) is the same length as but has a distinct N-terminus, compared to isoform 1. Both variants 2 and 3 encode the same isoform.
    Source sequence(s)
    AC010328, DA075573, DA692431, R40095
    Consensus CDS
    CCDS12860.1
    UniProtKB/Swiss-Prot
    Q09FC8
    Related
    ENSP00000395055.2, ENST00000421033.5
    Conserved Domains (3) summary
    COG5048
    Location:244539
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:358378
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:646
    KRAB; KRAB box
  3. NM_001330759.2NP_001317688.1  zinc finger protein 415 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC010328, AY283600, DA367299
    Consensus CDS
    CCDS82393.1
    UniProtKB/Swiss-Prot
    Q09FC8
    Conserved Domains (2) summary
    COG5048
    Location:14309
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:128148
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. NM_001330766.2NP_001317695.1  zinc finger protein 415 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) uses an alternate splice site near the 5' end and includes 3 alternate exons, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). Variants 4, 8, 9, and 10 encode the same protein (isoform 3).
    Source sequence(s)
    AC010328, AK095504, AY283600
    UniProtKB/Swiss-Prot
    Q09FC8
    UniProtKB/TrEMBL
    B3KTG1
    Conserved Domains (2) summary
    COG5048
    Location:292587
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:406426
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. NM_001352130.2NP_001339059.1  zinc finger protein 415 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC010328, AK095504, AY283600, DA348212, DA692431
    Conserved Domains (3) summary
    COG5048
    Location:321616
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:435455
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:645
    KRAB; KRAB box
  6. NM_001352131.2NP_001339060.1  zinc finger protein 415 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC010328, AK095504, AY283600, DA348212, DA518713, DA692431
    Conserved Domains (3) summary
    COG5048
    Location:321616
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:435455
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:645
    KRAB; KRAB box
  7. NM_001352132.2NP_001339061.1  zinc finger protein 415 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC010328, CN426971, DA692431, DB173728, R40095
    Conserved Domains (2) summary
    COG5048
    Location:292587
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:406426
    ZF_C2H2; C2H2 Zn finger [structural motif]
  8. NM_001352133.2NP_001339062.1  zinc finger protein 415 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC010328, CN426971, DA348212, DA692431, DB173728, R40095
    Conserved Domains (2) summary
    COG5048
    Location:292587
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:406426
    ZF_C2H2; C2H2 Zn finger [structural motif]
  9. NM_001352134.2NP_001339063.1  zinc finger protein 415 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC010328, CN426971, DA348212, DA692431, DB173728, DQ925696, R40095
    Conserved Domains (2) summary
    COG5048
    Location:292587
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:406426
    ZF_C2H2; C2H2 Zn finger [structural motif]
  10. NM_001352135.2NP_001339064.1  zinc finger protein 415 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC010328, DB026064, DB052912, R40095
    Conserved Domains (3) summary
    COG5048
    Location:290585
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:404424
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:5192
    KRAB; KRAB box
  11. NM_001352136.2NP_001339065.1  zinc finger protein 415 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC010328, CN426971, DA692431, EL736353, R40095
    Conserved Domains (3) summary
    COG5048
    Location:280575
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:394414
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:645
    KRAB; KRAB box
  12. NM_001352137.2NP_001339066.1  zinc finger protein 415 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC010328, DA348212, DA692431, EL736353, R40095
    Conserved Domains (3) summary
    COG5048
    Location:280575
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:394414
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:645
    KRAB; KRAB box
  13. NM_001352138.2NP_001339067.1  zinc finger protein 415 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC010328, DA692431, DB173728, R40095
    Conserved Domains (2) summary
    COG5048
    Location:256551
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:370390
    ZF_C2H2; C2H2 Zn finger [structural motif]
  14. NM_001352139.2NP_001339068.1  zinc finger protein 415 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC010328, DA692431, DB223753, R40095
    Conserved Domains (2) summary
    COG5048
    Location:256551
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:370390
    ZF_C2H2; C2H2 Zn finger [structural motif]
  15. NM_001352140.2NP_001339069.1  zinc finger protein 415 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC010328, DA348212, DA692431, DQ925696, R40095
    Conserved Domains (2) summary
    COG5048
    Location:256551
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:370390
    ZF_C2H2; C2H2 Zn finger [structural motif]
  16. NM_001352141.2NP_001339070.1  zinc finger protein 415 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC010328, DA348212, DA692431, DB173728, R40095
    Conserved Domains (2) summary
    COG5048
    Location:256551
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:370390
    ZF_C2H2; C2H2 Zn finger [structural motif]
  17. NM_001352142.2NP_001339071.1  zinc finger protein 415 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC010328, CN426971, DA518713, DA692431, R40095
    Consensus CDS
    CCDS54313.1
    Conserved Domains (3) summary
    COG5048
    Location:244539
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:358378
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:646
    KRAB; KRAB box
  18. NM_001352143.2NP_001339072.1  zinc finger protein 415 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC010328, DA348212, DA518713, DA692431, R40095
    Consensus CDS
    CCDS54313.1
    Conserved Domains (3) summary
    COG5048
    Location:244539
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:358378
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:646
    KRAB; KRAB box
  19. NM_001352144.2NP_001339073.1  zinc finger protein 415 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC010328, AK095504, DA348212, DA518713, DA692431, R40095
    Consensus CDS
    CCDS54313.1
    Conserved Domains (3) summary
    COG5048
    Location:244539
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:358378
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:646
    KRAB; KRAB box
  20. NM_001352146.2NP_001339075.1  zinc finger protein 415 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC010328, DA692431, DA767859, R40095
    Consensus CDS
    CCDS12860.1
    Conserved Domains (3) summary
    COG5048
    Location:244539
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:358378
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:646
    KRAB; KRAB box
  21. NM_001352147.2NP_001339076.1  zinc finger protein 415 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC010328, BC069668, DA692431, R40095
    Conserved Domains (2) summary
    COG5048
    Location:231526
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:345365
    ZF_C2H2; C2H2 Zn finger [structural motif]
  22. NM_001352148.2NP_001339077.1  zinc finger protein 415 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC010328, BC069668, DA505759, DA692431, R40095
    Conserved Domains (2) summary
    COG5048
    Location:231526
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:345365
    ZF_C2H2; C2H2 Zn finger [structural motif]
  23. NM_001352149.2NP_001339078.1  zinc finger protein 415 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC010328, AK095504, BC069668, DA505759, R40095
    Conserved Domains (2) summary
    COG5048
    Location:231526
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:345365
    ZF_C2H2; C2H2 Zn finger [structural motif]
  24. NM_001352150.2NP_001339079.1  zinc finger protein 415 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC010328, DA099143, DA692431, R40095
    Consensus CDS
    CCDS82393.1
    Related
    ENSP00000472911.1, ENST00000601493.5
    Conserved Domains (2) summary
    COG5048
    Location:14309
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:128148
    ZF_C2H2; C2H2 Zn finger [structural motif]
  25. NM_001352151.2NP_001339080.1  zinc finger protein 415 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC010328, AK095504, BC069668, DA348212, DA692431, R40095
    Consensus CDS
    CCDS82393.1
    Conserved Domains (2) summary
    COG5048
    Location:14309
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:128148
    ZF_C2H2; C2H2 Zn finger [structural motif]
  26. NM_018355.4NP_060825.2  zinc finger protein 415 isoform 2

    See identical proteins and their annotated locations for NP_060825.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 5' UTR and an alternate exon containing a distinct start codon, compared to variant 1. The resulting isoform (2) is the same length as but has a distinct N-terminus, compared to isoform 1. Variants 2, 3 and 21 encode the same protein (isoform 2).
    Source sequence(s)
    AA125787, AK002053, BC069668, DA692431, R40095
    Consensus CDS
    CCDS12860.1
    UniProtKB/Swiss-Prot
    Q09FC8
    Related
    ENSP00000243643.3, ENST00000243643.9
    Conserved Domains (3) summary
    COG5048
    Location:244539
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:358378
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:646
    KRAB; KRAB box

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    53107879..53132952 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024451600.1XP_024307368.1  zinc finger protein 415 isoform X3

    Conserved Domains (3) summary
    COG5048
    Location:321616
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:435455
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:645
    KRAB; KRAB box
  2. XM_024451597.1XP_024307365.1  zinc finger protein 415 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:321616
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:435455
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:545
    KRAB; KRAB box
  3. XM_006723279.1XP_006723342.1  zinc finger protein 415 isoform X9

    See identical proteins and their annotated locations for XP_006723342.1

    UniProtKB/Swiss-Prot
    Q09FC8
    Conserved Domains (2) summary
    COG5048
    Location:231526
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:345365
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. XM_006723280.3XP_006723343.2  zinc finger protein 415 isoform X10

    Conserved Domains (2) summary
    COG5048
    Location:14309
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:128148
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. XM_006723267.1XP_006723330.1  zinc finger protein 415 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:321616
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:435455
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:545
    KRAB; KRAB box
  6. XM_017026957.1XP_016882446.1  zinc finger protein 415 isoform X4

    Conserved Domains (2) summary
    COG5048
    Location:292587
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:406426
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. XM_017026969.1XP_016882458.1  zinc finger protein 415 isoform X11

  8. XM_011527101.2XP_011525403.1  zinc finger protein 415 isoform X6

    See identical proteins and their annotated locations for XP_011525403.1

    Conserved Domains (3) summary
    COG5048
    Location:280575
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:394414
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:645
    KRAB; KRAB box
  9. XM_017026970.1XP_016882459.1  zinc finger protein 415 isoform X12

    UniProtKB/Swiss-Prot
    Q09FC8
    Conserved Domains (2) summary
    COG5048
    Location:256551
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:370390
    ZF_C2H2; C2H2 Zn finger [structural motif]
  10. XM_017026956.1XP_016882445.1  zinc finger protein 415 isoform X4

    Conserved Domains (2) summary
    COG5048
    Location:292587
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:406426
    ZF_C2H2; C2H2 Zn finger [structural motif]
  11. XM_024451596.1XP_024307364.1  zinc finger protein 415 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:321616
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:435455
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:545
    KRAB; KRAB box
  12. XM_017026968.1XP_016882457.1  zinc finger protein 415 isoform X9

    UniProtKB/Swiss-Prot
    Q09FC8
    Conserved Domains (2) summary
    COG5048
    Location:231526
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:345365
    ZF_C2H2; C2H2 Zn finger [structural motif]
  13. XM_017026961.1XP_016882450.1  zinc finger protein 415 isoform X5

  14. XM_017026971.1XP_016882460.1  zinc finger protein 415 isoform X7

    Conserved Domains (2) summary
    COG5048
    Location:272567
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:386406
    ZF_C2H2; C2H2 Zn finger [structural motif]
  15. XM_017026960.1XP_016882449.1  zinc finger protein 415 isoform X4

    Conserved Domains (2) summary
    COG5048
    Location:292587
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:406426
    ZF_C2H2; C2H2 Zn finger [structural motif]
  16. XM_017026964.1XP_016882453.1  zinc finger protein 415 isoform X8

    UniProtKB/Swiss-Prot
    Q09FC8
    Conserved Domains (3) summary
    COG5048
    Location:244539
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:358378
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:646
    KRAB; KRAB box
  17. XM_024451599.1XP_024307367.1  zinc finger protein 415 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:321616
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:435455
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:545
    KRAB; KRAB box
  18. XM_024451601.1XP_024307369.1  zinc finger protein 415 isoform X7

    Conserved Domains (2) summary
    COG5048
    Location:272567
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:386406
    ZF_C2H2; C2H2 Zn finger [structural motif]
  19. XM_024451595.1XP_024307363.1  zinc finger protein 415 isoform X1

    Conserved Domains (3) summary
    COG5048
    Location:367662
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:481501
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:5191
    KRAB; KRAB box
  20. XM_024451598.1XP_024307366.1  zinc finger protein 415 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:321616
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:435455
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:545
    KRAB; KRAB box
Support Center