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ZNF823 zinc finger protein 823 [ Homo sapiens (human) ]

Gene ID: 55552, updated on 12-Oct-2019

Summary

Official Symbol
ZNF823provided by HGNC
Official Full Name
zinc finger protein 823provided by HGNC
Primary source
HGNC:HGNC:30936
See related
Ensembl:ENSG00000197933
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HSZFP36
Expression
Ubiquitous expression in esophagus (RPKM 2.9), colon (RPKM 2.7) and 25 other tissues See more
Orthologs

Genomic context

See ZNF823 in Genome Data Viewer
Location:
19p13.2
Exon count:
5
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (11721265..11738997, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (11832080..11849824, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein A1 pseudogene 10 Neighboring gene zinc finger protein 833, pseudogene Neighboring gene zinc finger protein 441 Neighboring gene zinc finger protein 491

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 823
Names
ZFP 36 for a zinc finger protein
zinc finger protein ZFP-36

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080493.4NP_001073962.1  zinc finger protein 823 isoform 1

    See identical proteins and their annotated locations for NP_001073962.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    BC052597, DA519419
    Consensus CDS
    CCDS45981.1
    UniProtKB/Swiss-Prot
    P16415
    Related
    ENSP00000340683.5, ENST00000341191.11
    Conserved Domains (5) summary
    smart00349
    Location:440
    KRAB; krueppel associated box
    COG5048
    Location:109546
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:501521
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:440
    KRAB; KRAB box
    pfam13465
    Location:513537
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001297610.2NP_001284539.1  zinc finger protein 823 isoform 3

    See identical proteins and their annotated locations for NP_001284539.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 3, which has a shorter N-terminus, compared to isoform 1
    Source sequence(s)
    AK303213, BC052597
    UniProtKB/Swiss-Prot
    P16415
    Conserved Domains (3) summary
    COG5048
    Location:9392
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:319339
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:331355
    zf-H2C2_2; Zinc-finger double domain
  3. NM_017507.2NP_059977.1  zinc finger protein 823 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 2, which has a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AK308189, BC052597, DA519419
    UniProtKB/Swiss-Prot
    P16415
    Related
    ENSP00000410654.1, ENST00000431998.1
    Conserved Domains (3) summary
    COG5048
    Location:65502
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:457477
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:469493
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    11721265..11738997 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017026942.1XP_016882431.1  zinc finger protein 823 isoform X2

    UniProtKB/Swiss-Prot
    P16415
    Conserved Domains (3) summary
    COG5048
    Location:9392
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:319339
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:331355
    zf-H2C2_2; Zinc-finger double domain
  2. XM_017026941.1XP_016882430.1  zinc finger protein 823 isoform X2

    UniProtKB/Swiss-Prot
    P16415
    Conserved Domains (3) summary
    COG5048
    Location:9392
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:319339
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:331355
    zf-H2C2_2; Zinc-finger double domain
  3. XM_024451586.1XP_024307354.1  zinc finger protein 823 isoform X1

    Conserved Domains (3) summary
    COG5048
    Location:77514
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:469489
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:510534
    zf-H2C2_2; Zinc-finger double domain
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