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TASOR2 transcription activation suppressor family member 2 [ Homo sapiens (human) ]

Gene ID: 54906, updated on 5-Sep-2021

Summary

Official Symbol
TASOR2provided by HGNC
Official Full Name
transcription activation suppressor family member 2provided by HGNC
Primary source
HGNC:HGNC:23484
See related
Ensembl:ENSG00000108021
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM208B; C10orf18; bA318E3.2
Expression
Ubiquitous expression in testis (RPKM 8.3), thyroid (RPKM 5.1) and 25 other tissues See more
Orthologs
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Genomic context

See TASOR2 in Genome Data Viewer
Location:
10p15.1
Exon count:
28
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (5684759..5765779)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (5726801..5805703)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107984199 Neighboring gene RNA, 7SL, cytoplasmic 445, pseudogene Neighboring gene ankyrin repeat and SOCS box containing 13 Neighboring gene GDP dissociation inhibitor 2 Neighboring gene nuclear receptor binding factor 2 pseudogene 5 Neighboring gene tRNA-Val (anticodon TAC) 3-1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
Genome-wide association study identifies two susceptibility loci for osteosarcoma.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20360, DKFZp781E1986

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
protein TASOR 2
Names
family with sequence similarity 208 member B
protein FAM208B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_021250.1 RefSeqGene

    Range
    5001..83903
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001321783.2NP_001308712.2  protein TASOR 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL365356, AL596094
    Consensus CDS
    CCDS41485.1
    Conserved Domains (2) summary
    pfam12480
    Location:94167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:552701
    DUF3715; Protein of unknown function (DUF3715)
  2. NM_001321784.2NP_001308713.2  protein TASOR 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL365356, AL596094
    Consensus CDS
    CCDS41485.1
    Conserved Domains (2) summary
    pfam12480
    Location:94167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:552701
    DUF3715; Protein of unknown function (DUF3715)
  3. NM_001321785.2NP_001308714.2  protein TASOR 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL365356, AL596094
    Conserved Domains (2) summary
    pfam12480
    Location:94167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:471620
    DUF3715; Protein of unknown function (DUF3715)
  4. NM_001387328.1NP_001374257.1  protein TASOR 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL365356, AL596094
    Related
    ENSP00000496466.1, ENST00000645567.1
    Conserved Domains (2) summary
    pfam12480
    Location:309382
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:767916
    DUF3715; Protein of unknown function (DUF3715)
  5. NM_017782.5NP_060252.5  protein TASOR 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL365356, AL596094
    Consensus CDS
    CCDS41485.1
    Related
    ENSP00000328426.5, ENST00000328090.9
    Conserved Domains (2) summary
    pfam12480
    Location:94167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:552701
    DUF3715; Protein of unknown function (DUF3715)

RNA

  1. NR_135800.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL365356, R42352

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    5684759..5765779
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005252480.5XP_005252537.1  protein TASOR 2 isoform X9

    See identical proteins and their annotated locations for XP_005252537.1

    UniProtKB/Swiss-Prot
    Q5VWN6
    Conserved Domains (2) summary
    pfam12480
    Location:94167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:552701
    DUF3715; Protein of unknown function (DUF3715)
  2. XM_017016362.2XP_016871851.1  protein TASOR 2 isoform X10

    Conserved Domains (2) summary
    pfam12480
    Location:243316
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:701850
    DUF3715; Protein of unknown function (DUF3715)
  3. XM_017016364.2XP_016871853.1  protein TASOR 2 isoform X12

    Conserved Domains (2) summary
    pfam12480
    Location:197270
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:655804
    DUF3715; Protein of unknown function (DUF3715)
  4. XM_011519521.3XP_011517823.1  protein TASOR 2 isoform X11

    See identical proteins and their annotated locations for XP_011517823.1

    Conserved Domains (2) summary
    pfam12480
    Location:231304
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:689838
    DUF3715; Protein of unknown function (DUF3715)
  5. XM_005252476.5XP_005252533.1  protein TASOR 2 isoform X13

    Conserved Domains (2) summary
    pfam12480
    Location:185258
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:643792
    DUF3715; Protein of unknown function (DUF3715)
  6. XM_017016365.2XP_016871854.1  protein TASOR 2 isoform X9

    UniProtKB/Swiss-Prot
    Q5VWN6
    Conserved Domains (2) summary
    pfam12480
    Location:94167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:552701
    DUF3715; Protein of unknown function (DUF3715)
  7. XM_005252475.4XP_005252532.1  protein TASOR 2 isoform X9

    See identical proteins and their annotated locations for XP_005252532.1

    UniProtKB/Swiss-Prot
    Q5VWN6
    Conserved Domains (2) summary
    pfam12480
    Location:94167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:552701
    DUF3715; Protein of unknown function (DUF3715)
  8. XM_017016363.2XP_016871852.1  protein TASOR 2 isoform X9

    UniProtKB/Swiss-Prot
    Q5VWN6
    Conserved Domains (2) summary
    pfam12480
    Location:94167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:552701
    DUF3715; Protein of unknown function (DUF3715)
  9. XM_011519518.3XP_011517820.1  protein TASOR 2 isoform X5

    Conserved Domains (2) summary
    pfam12480
    Location:329402
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:76222
    DUF3715; Protein of unknown function (DUF3715)
  10. XM_005252481.5XP_005252538.1  protein TASOR 2 isoform X9

    See identical proteins and their annotated locations for XP_005252538.1

    UniProtKB/Swiss-Prot
    Q5VWN6
    Conserved Domains (2) summary
    pfam12480
    Location:94167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:552701
    DUF3715; Protein of unknown function (DUF3715)
  11. XM_011519517.3XP_011517819.1  protein TASOR 2 isoform X3

    Conserved Domains (2) summary
    pfam12480
    Location:355428
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:102248
    DUF3715; Protein of unknown function (DUF3715)
  12. XM_011519522.3XP_011517824.1  protein TASOR 2 isoform X11

    See identical proteins and their annotated locations for XP_011517824.1

    Conserved Domains (2) summary
    pfam12480
    Location:231304
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:689838
    DUF3715; Protein of unknown function (DUF3715)
  13. XM_011519515.3XP_011517817.1  protein TASOR 2 isoform X1

    See identical proteins and their annotated locations for XP_011517817.1

    Conserved Domains (2) summary
    pfam12480
    Location:380453
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:127273
    DUF3715; Protein of unknown function (DUF3715)
  14. XM_011519519.3XP_011517821.1  protein TASOR 2 isoform X6

    Conserved Domains (2) summary
    pfam12480
    Location:380453
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:127273
    DUF3715; Protein of unknown function (DUF3715)
  15. XM_005252474.4XP_005252531.1  protein TASOR 2 isoform X4

    Conserved Domains (2) summary
    pfam12480
    Location:334407
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:792941
    DUF3715; Protein of unknown function (DUF3715)
  16. XM_011519520.3XP_011517822.1  protein TASOR 2 isoform X8

    Conserved Domains (2) summary
    pfam12480
    Location:279352
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:737886
    DUF3715; Protein of unknown function (DUF3715)
  17. XM_011519516.2XP_011517818.1  protein TASOR 2 isoform X2

    See identical proteins and their annotated locations for XP_011517818.1

    Conserved Domains (2) summary
    pfam12480
    Location:380453
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:127273
    DUF3715; Protein of unknown function (DUF3715)
  18. XM_017016361.1XP_016871850.1  protein TASOR 2 isoform X7

    Conserved Domains (2) summary
    pfam12480
    Location:380453
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:127273
    DUF3715; Protein of unknown function (DUF3715)
  19. XM_005252482.3XP_005252539.1  protein TASOR 2 isoform X9

    See identical proteins and their annotated locations for XP_005252539.1

    UniProtKB/Swiss-Prot
    Q5VWN6
    Conserved Domains (2) summary
    pfam12480
    Location:94167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:552701
    DUF3715; Protein of unknown function (DUF3715)
  20. XM_011519525.3XP_011517827.1  protein TASOR 2 isoform X9

    See identical proteins and their annotated locations for XP_011517827.1

    UniProtKB/Swiss-Prot
    Q5VWN6
    Conserved Domains (2) summary
    pfam12480
    Location:94167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:552701
    DUF3715; Protein of unknown function (DUF3715)
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