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TASOR2 transcription activation suppressor family member 2 [ Homo sapiens (human) ]

Gene ID: 54906, updated on 4-Dec-2022

Summary

Official Symbol
TASOR2provided by HGNC
Official Full Name
transcription activation suppressor family member 2provided by HGNC
Primary source
HGNC:HGNC:23484
See related
Ensembl:ENSG00000108021 AllianceGenome:HGNC:23484
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM208B; C10orf18; bA318E3.2
Summary
Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis (RPKM 8.3), thyroid (RPKM 5.1) and 25 other tissues See more
Orthologs
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Genomic context

See TASOR2 in Genome Data Viewer
Location:
10p15.1
Exon count:
27
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (5684838..5763740)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (5688634..5767529)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (5726801..5805703)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107984199 Neighboring gene RNA, 7SL, cytoplasmic 445, pseudogene Neighboring gene ankyrin repeat and SOCS box containing 13 Neighboring gene Sharpr-MPRA regulatory region 2494 Neighboring gene GDP dissociation inhibitor 2 Neighboring gene nuclear receptor binding factor 2 pseudogene 5 Neighboring gene uncharacterized LOC124902367

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20360, DKFZp781E1986

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in negative regulation of gene expression, epigenetic IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
protein TASOR 2
Names
family with sequence similarity 208 member B
protein FAM208B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_021250.2 RefSeqGene

    Range
    5002..83904
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001321783.2NP_001308712.2  protein TASOR 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL365356, AL596094
    Consensus CDS
    CCDS41485.1
    UniProtKB/Swiss-Prot
    Q9NXA1
    Related
    ENSP00000512130.1, ENST00000695737.1
    Conserved Domains (2) summary
    pfam12480
    Location:94167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:552701
    DUF3715; Protein of unknown function (DUF3715)
  2. NM_001321784.2NP_001308713.2  protein TASOR 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL365356, AL596094
    Consensus CDS
    CCDS41485.1
    UniProtKB/Swiss-Prot
    Q9NXA1
    Related
    ENSP00000512207.1, ENST00000695834.1
    Conserved Domains (2) summary
    pfam12480
    Location:94167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:552701
    DUF3715; Protein of unknown function (DUF3715)
  3. NM_001321785.2NP_001308714.2  protein TASOR 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL365356, AL596094
    Consensus CDS
    CCDS91209.1
    UniProtKB/TrEMBL
    A0A8Q3SI84
    Related
    ENSP00000512206.1, ENST00000695833.1
    Conserved Domains (2) summary
    pfam12480
    Location:94167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:471620
    DUF3715; Protein of unknown function (DUF3715)
  4. NM_001387328.1NP_001374257.1  protein TASOR 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL365356, AL596094
    Consensus CDS
    CCDS91208.1
    UniProtKB/TrEMBL
    A0A2R8YH03
    Related
    ENSP00000496466.1, ENST00000645567.1
    Conserved Domains (2) summary
    pfam12480
    Location:309382
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:767916
    DUF3715; Protein of unknown function (DUF3715)
  5. NM_017782.5NP_060252.5  protein TASOR 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL365356, AL596094
    Consensus CDS
    CCDS41485.1
    UniProtKB/Swiss-Prot
    Q9NXA1
    Related
    ENSP00000328426.5, ENST00000328090.9
    Conserved Domains (2) summary
    pfam12480
    Location:94167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:552701
    DUF3715; Protein of unknown function (DUF3715)

RNA

  1. NR_135800.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL365356, R42352

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    5684838..5763740
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    5688634..5767529
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)