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Tasor2 transcription activation suppressor family member 2 [ Mus musculus (house mouse) ]

Gene ID: 105203, updated on 26-Sep-2022

Summary

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Official Symbol
Tasor2provided by MGI
Official Full Name
transcription activation suppressor family member 2provided by MGI
Primary source
MGI:MGI:2145274
See related
Ensembl:ENSMUSG00000033799 AllianceGenome:MGI:2145274
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pap20; Fam208b; mKIAA2006
Summary
Predicted to be located in cytosol. Predicted to be active in nucleoplasm. Orthologous to human TASOR2 (transcription activation suppressor family member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 6.7), CNS E11.5 (RPKM 4.2) and 24 other tissues See more
Orthologs
human all
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Genomic context

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See Tasor2 in Genome Data Viewer
Location:
13; 13 A1
Exon count:
23
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (3615905..3661108, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (3566035..3612884, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2810429I04 gene Neighboring gene predicted gene, 40654 Neighboring gene guanosine diphosphate (GDP) dissociation inhibitor 2 Neighboring gene general transcription factor II A, 2 pseudogene Neighboring gene ankyrin repeat and SOCS box-containing 13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Developmental regulation of membrane traffic organization during synaptogenesis in mouse diaphragm muscle. Antony C, et al. J Cell Biol, 1995 Aug. PMID 7642711, Free PMC Article
  2. Two-hybrid system screen with the small GTP-binding protein Rab6. Identification of a novel mouse GDP dissociation inhibitor isoform and two other potential partners of Rab6. Janoueix-Lerosey I, et al. J Biol Chem, 1995 Jun 16. PMID 7782346
  3. Characterization of the zinc-induced Shank3 interactome of mouse synaptosome. Lee Y, et al. Biochem Biophys Res Commun, 2017 Dec 16. PMID 29111324
  4. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  5. The central role of EED in the orchestration of polycomb group complexes. Cao Q, et al. Nat Commun, 2014. PMID 24457600, Free PMC Article

See all (18) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • KIAA2006, MGC25933

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
protein TASOR 2
Names
PBR associated protein
family with sequence similarity 208, member B
peripheral benzodiazepine receptor-associated protein 20
peripherial benzodiazepine receptor associated protein
protein FAM208B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360838.1 → NP_001347767.1  protein TASOR 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC129597
    Conserved Domains (2) summary
    pfam12480
    Location:94 → 167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:547 → 699
    DUF3715; Protein of unknown function (DUF3715)

  2. NM_134063.3 → NP_598824.3  protein TASOR 2 isoform 1

    See identical proteins and their annotated locations for NP_598824.3

    Status: VALIDATED

    Source sequence(s)
    AK138119, AK220437, BC085160
    Consensus CDS
    CCDS49201.1
    UniProtKB/Swiss-Prot
    Q5DTT3, Q91W76
    Related
    ENSMUSP00000093774.4, ENSMUST00000096069.5
    Conserved Domains (2) summary
    pfam12480
    Location:94 → 167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:547 → 699
    DUF3715; Protein of unknown function (DUF3715)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    3615905..3661108 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006516463.3 → XP_006516526.1  protein TASOR 2 isoform X2

    Conserved Domains (1) summary
    pfam12509
    Location:325 → 477
    DUF3715; Protein of unknown function (DUF3715)

  2. XM_006516460.4 → XP_006516523.1  protein TASOR 2 isoform X1

    See identical proteins and their annotated locations for XP_006516523.1

    UniProtKB/Swiss-Prot
    Q5DTT3, Q91W76
    Conserved Domains (2) summary
    pfam12480
    Location:94 → 167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:547 → 699
    DUF3715; Protein of unknown function (DUF3715)

  3. XM_006516461.5 → XP_006516524.1  protein TASOR 2 isoform X1

    See identical proteins and their annotated locations for XP_006516524.1

    UniProtKB/Swiss-Prot
    Q5DTT3, Q91W76
    Conserved Domains (2) summary
    pfam12480
    Location:94 → 167
    DUF3699; Protein of unknown function (DUF3699)
    pfam12509
    Location:547 → 699
    DUF3715; Protein of unknown function (DUF3715)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5DTT3.2 GenPept UniProtKB/Swiss-Prot:Q5DTT3

Gene LinkOut

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