Format

Send to:

Choose Destination

TMA7 translation machinery associated 7 homolog [ Homo sapiens (human) ]

Gene ID: 51372, updated on 24-Nov-2020

Summary

Official Symbol
TMA7provided by HGNC
Official Full Name
translation machinery associated 7 homologprovided by HGNC
Primary source
HGNC:HGNC:26932
See related
Ensembl:ENSG00000232112 MIM:615808
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CCDC72; HSPC016
Expression
Ubiquitous expression in colon (RPKM 126.7), bone marrow (RPKM 115.6) and 25 other tissues See more
Orthologs

Genomic context

See TMA7 in Genome Data Viewer
Location:
3p21.31
Exon count:
4
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (48440257..48444208)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (48481686..48485537)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene F-box and WD repeat domain containing 12 Neighboring gene RNA, 7SL, cytoplasmic 321, pseudogene Neighboring gene plexin B1 Neighboring gene uncharacterized LOC105377077 Neighboring gene coiled-coil domain containing 51 Neighboring gene ATRIP-TREX1 readthrough Neighboring gene ATR interacting protein Neighboring gene three prime repair exonuclease 1 Neighboring gene shisa family member 5

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
translation machinery-associated protein 7
Names
coiled-coil domain containing 72
coiled-coil domain-containing protein 72
translational machinery associated 7 homolog

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001329417.2NP_001316346.1  translation machinery-associated protein 7 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice junction in the 3' end of the coding sequence compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is 2 aa shorter compared to isoform 1.
    Source sequence(s)
    AA149268, AI339191, BU536461
  2. NM_015933.6NP_057017.1  translation machinery-associated protein 7 isoform 1

    See identical proteins and their annotated locations for NP_057017.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
    Source sequence(s)
    AA149268, BU536461
    Consensus CDS
    CCDS46823.1
    UniProtKB/Swiss-Prot
    Q9Y2S6
    UniProtKB/TrEMBL
    A0A024R306
    Related
    ENSP00000397843.2, ENST00000438607.2
    Conserved Domains (1) summary
    pfam09072
    Location:364
    TMA7; Translation machinery associated TMA7

RNA

  1. NR_137639.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate splice junction compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    AA149268, AL712164, BU536461

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    48440257..48444208
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center