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CERS2 ceramide synthase 2 [ Canis lupus familiaris (dog) ]

Gene ID: 483187, updated on 17-Aug-2024

Summary

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Official Symbol
CERS2provided by VGNC
Official Full Name
ceramide synthase 2provided by VGNC
Primary source
VGNC:VGNC:39148
See related
Ensembl:ENSCAFG00845020459
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
LASS2
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 17
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 17 NC_051821.1 (61085850..61094878, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 17 NC_006599.4 (59513854..59522875, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 17 NC_049238.1 (60727161..60736178, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 17 NC_049277.1 (59914771..59918641, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 17 NC_049758.1 (59999724..60008740, complement)

Chromosome 17 - NC_051821.1Genomic Context describing neighboring genes Neighboring gene cortexin domain containing 2 Neighboring gene uncharacterized LOC111090720 Neighboring gene U2 spliceosomal RNA Neighboring gene SET domain bifurcated histone lysine methyltransferase 1 Neighboring gene annexin A9 Neighboring gene MINDY lysine 48 deubiquitinase 1 Neighboring gene prune exopolyphosphatase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sphingosine N-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LAG1 longevity assurance homolog 2; LOW QUALITY PROTEIN: ceramide synthase 2; ceramide synthase 2
Names
LAG1 homolog, ceramide synthase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051821.1 Reference ROS_Cfam_1.0

    Range
    61085850..61094878 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038423095.1 → XP_038279023.1  ceramide synthase 2

    UniProtKB/TrEMBL
    A0A8C0MKB8, A0A8C0R0N6, A0A8C0SCD5, A0A8I3P4B7
    Related
    ENSCAFP00845028209.1, ENSCAFT00845036044.1
    Conserved Domains (2) summary
    smart00724
    Location:131 → 332
    TLC; TRAM, LAG1 and CLN8 homology domains
    cd00086
    Location:71 → 128
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

  2. XM_038423096.1 → XP_038279024.1  ceramide synthase 2

    UniProtKB/TrEMBL
    A0A8C0MKB8, A0A8C0R0N6, A0A8C0SCD5, A0A8I3P4B7
    Conserved Domains (2) summary
    smart00724
    Location:131 → 332
    TLC; TRAM, LAG1 and CLN8 homology domains
    cd00086
    Location:71 → 128
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049277.1 Alternate UMICH_Zoey_3.1

    Range
    59914771..59918641 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038499591.1 → XP_038355519.1  LOW QUALITY PROTEIN: ceramide synthase 2

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049758.1 Alternate UNSW_CanFamBas_1.0

    Range
    59999724..60008740 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038626255.1 → XP_038482183.1  ceramide synthase 2

    Conserved Domains (2) summary
    smart00724
    Location:131 → 332
    TLC; TRAM, LAG1 and CLN8 homology domains
    cd00086
    Location:71 → 128
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

  2. XM_038626256.1 → XP_038482184.1  ceramide synthase 2

    Conserved Domains (2) summary
    smart00724
    Location:131 → 332
    TLC; TRAM, LAG1 and CLN8 homology domains
    cd00086
    Location:71 → 128
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049238.1 Alternate UU_Cfam_GSD_1.0

    Range
    60727161..60736178 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038562160.1 → XP_038418088.1  ceramide synthase 2

    UniProtKB/TrEMBL
    A0A8C0MKB8, A0A8C0R0N6, A0A8C0SCD5, A0A8I3P4B7
    Conserved Domains (2) summary
    smart00724
    Location:131 → 332
    TLC; TRAM, LAG1 and CLN8 homology domains
    cd00086
    Location:71 → 128
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

  2. XM_038562161.1 → XP_038418089.1  ceramide synthase 2

    UniProtKB/TrEMBL
    A0A8C0MKB8, A0A8C0R0N6, A0A8C0SCD5, A0A8I3P4B7
    Conserved Domains (2) summary
    smart00724
    Location:131 → 332
    TLC; TRAM, LAG1 and CLN8 homology domains
    cd00086
    Location:71 → 128
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    59513854..59522875 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038453206.1 → XP_038309134.1  ceramide synthase 2

    UniProtKB/TrEMBL
    A0A8C0MKB8, A0A8C0R0N6, A0A8C0SCD5, A0A8I3P4B7
    Conserved Domains (2) summary
    smart00724
    Location:131 → 332
    TLC; TRAM, LAG1 and CLN8 homology domains
    cd00086
    Location:71 → 128
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

  2. XM_038453207.1 → XP_038309135.1  ceramide synthase 2

    UniProtKB/TrEMBL
    A0A8C0MKB8, A0A8C0R0N6, A0A8C0SCD5, A0A8I3P4B7
    Conserved Domains (2) summary
    smart00724
    Location:131 → 332
    TLC; TRAM, LAG1 and CLN8 homology domains
    cd00086
    Location:71 → 128
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
Nucleotide Protein
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